| RS76401964 |
PNPT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation defect type 13, Inborn genetic diseases |
| RS764019690 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS764020019 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS764020784 |
RAB11A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764022114 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS764023083 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS764023822 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS764024269 |
RP1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS764025364 |
CHM
|
Health Risk |
Pathogenic |
Choroideremia, Choroideremia |
| RS764025875 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Pituitary adenoma 5, multiple types |
| RS764026145 |
TNFRSF6B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764026385 |
FOXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Otosclerosis 11, Otosclerosis 11 |
| RS764026969 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiac arrhythmia |
| RS764027029 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS764028295 |
YARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate C, Inborn genetic diseases |
| RS764028320 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS764028978 |
TGFB2
|
Health Risk |
Pathogenic |
Loeys-Dietz syndrome 4, Loeys-Dietz syndrome 4 |
| RS764029414 |
F2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital prothrombin deficiency, Thrombophilia due to thrombin defect |
| RS764029536 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, Idiopathic Pulmonary Fibrosis |
| RS764030196 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS764031568 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1AA, Primary familial hypertrophic cardiomyopathy |
| RS764035021 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764036283 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
POLG-related disorder, Progressive sclerosing poliodystrophy |
| RS764036360 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS764037565 |
HGD
|
Health Risk |
Conflicting classifications of pathogenicity |
Alkaptonuria, Alkaptonuria |
| RS764037830 |
SCN1A
|
Health Risk |
Pathogenic |
Severe myoclonic epilepsy in infancy, Severe myoclonic epilepsy in infancy |
| RS764038221 |
ROBO4
|
Health Risk |
Likely pathogenic |
Aortic valve disease 3, Bicuspid aortic valve |
| RS764039230 |
HMGCL
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of hydroxymethylglutaryl-CoA lyase, Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency |
| RS764039432 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS764040146 |
TGM1
|
Health Risk |
Likely pathogenic |
Autosomal recessive congenital ichthyosis 1, Lamellar ichthyosis |
| RS764040645 |
PLCG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 3, Familial cold autoinflammatory syndrome 3 |
| RS764041557 |
ATP7B
|
Health Risk |
Likely pathogenic |
Wilson disease, Wilson disease |
| RS764041869 |
TANC2
|
Health Risk |
Pathogenic/Likely pathogenic |
INTELLECTUAL DEVELOPMENTAL DISORDER WITH AUTISTIC FEATURES AND LANGUAGE DELAY WITHOUT SEIZURES, Neurodevelopmental disorder |
| RS764042245 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS764042837 |
HNF1B
|
Health Risk |
Pathogenic |
Renal cysts and diabetes syndrome, Renal cysts and diabetes syndrome |
| RS764042910 |
LDLR
|
Health Risk |
Likely pathogenic |
Hypercholesterolemia, familial |
| RS764043352 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS764045158 |
COL11A2
|
Health Risk |
Pathogenic/Likely pathogenic |
Fibrochondrogenesis 2, Autosomal recessive nonsyndromic hearing loss 53 |
| RS764045674 |
PCCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Propionic acidemia, Propionic acidemia |
| RS764046610 |
COL4A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hematuria, benign familial |
| RS764047509 |
KMT2E
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764048407 |
CFAP69
|
Health Risk |
Pathogenic |
Spermatogenic failure 24, Spermatogenic failure 24 |
| RS764051026 |
PPT1
|
Health Risk |
Likely pathogenic |
Neuronal ceroid lipofuscinosis 1, Neuronal ceroid lipofuscinosis 1 |
| RS764052634 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS764053163 |
TSEN2
|
Health Risk |
Likely pathogenic |
— |
| RS764053964 |
ASXL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe feeding difficulties-failure to thrive-microcephaly due to ASXL3 deficiency syndrome, Severe feeding difficulties-failure to thrive-microcephaly due to ASXL3 deficiency syndrome |
| RS764054659 |
FOXG1
|
Health Risk |
Conflicting classifications of pathogenicity |
FOXG1 disorder, FOXG1 disorder |
| RS764054683 |
ATP1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764055331 |
MMP2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764056784 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS764057581 |
SGSH
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-III-A |
| RS764057679 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS764058065 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, KBG syndrome |
| RS764058481 |
RTEL1
|
Health Risk |
Pathogenic |
Pulmonary fibrosis and/or bone marrow failure, Telomere-related |
| RS764059405 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS764059609 |
USH1C
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764060282 |
BMPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary pulmonary hypertension, Inborn genetic diseases |
| RS764060500 |
ETFDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS764060752 |
MME
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS764061176 |
EGF
|
Health Risk |
Likely pathogenic |
— |
| RS764062606 |
ERCC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Ovarian cancer, Ovarian cancer |
| RS764064217 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS764064779 |
NDUFA9
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex I deficiency, nuclear type 26 |
| RS764066045 |
DNAAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 13 |
| RS764066541 |
HR
|
Health Risk |
Pathogenic |
— |
| RS764067083 |
HADHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial trifunctional protein deficiency, Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency |
| RS764068013 |
TRPM1
|
Health Risk |
Likely pathogenic |
— |
| RS764070148 |
TNXB
|
Health Risk |
Pathogenic/Likely pathogenic |
Ehlers-Danlos syndrome due to tenascin-X deficiency, Cardiovascular phenotype |
| RS764070268 |
GALNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-IV-A |
| RS764070280 |
DNHD1
|
Health Risk |
Likely pathogenic |
Spermatogenic failure 65, Spermatogenic failure 65 |
| RS764071122 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS764072757 |
ASL
|
Health Risk |
Conflicting classifications of pathogenicity |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS764074545 |
BBS12
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 12 |
| RS764076380 |
TRMU
|
Health Risk |
Conflicting classifications of pathogenicity |
Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins, Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins |
| RS764078087 |
KCNJ1
|
Health Risk |
Pathogenic/Likely pathogenic |
Bartter syndrome, Bartter disease type 2 |
| RS764079291 |
NF1
|
Health Risk |
Pathogenic |
Neurofibromatosis, type 1 |
| RS764079701 |
HNF1B
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Maturity-onset diabetes of the young, Maturity-onset diabetes of the young |
| RS764079802 |
MCM4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764081252 |
VPS13A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764082747 |
HAX1
|
Health Risk |
Pathogenic/Likely pathogenic |
Kostmann syndrome, Severe congenital neutropenia |
| RS764084155 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Cardiomyopathy |
| RS764084156 |
G6PC1
|
Health Risk |
Likely pathogenic |
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA, Glycogen storage disease due to glucose-6-phosphatase deficiency type IA |
| RS764084563 |
SLC5A2
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial renal glucosuria, SLC5A2-related disorder |
| RS764085684 |
TBCD
|
Health Risk |
Pathogenic |
Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome, Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome |
| RS764085979 |
MLH1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS764086211 |
LRP2
|
Health Risk |
Likely pathogenic |
— |
| RS764086459 |
BLM
|
Health Risk |
Likely pathogenic |
Bloom syndrome, Bloom syndrome |
| RS764086464 |
CNGA1
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 49, Retinitis pigmentosa 49 |
| RS764086484 |
CAPN3
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Muscular dystrophy |
| RS764089304 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Cardiovascular phenotype |
| RS764090370 |
KIRREL1
|
Health Risk |
Pathogenic |
Nephrotic syndrome, type 23 |
| RS764091042 |
FANCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group B, Fanconi anemia |
| RS764091969 |
TCTN3
|
Health Risk |
Pathogenic/Likely pathogenic |
Orofacial-digital syndrome IV, Joubert syndrome 18 |
| RS764093382 |
LNPK
|
Health Risk |
Pathogenic |
— |
| RS764093488 |
EXT1
|
Health Risk |
Pathogenic |
Multiple congenital exostosis, Multiple congenital exostosis |
| RS764094211 |
KCNQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS764094665 |
FLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Ichthyosis vulgaris, Ichthyosis vulgaris |
| RS764094963 |
SLC38A8
|
Health Risk |
Pathogenic |
— |
| RS764095375 |
NIN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764095834 |
PRDM5
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |