| RS764495616 |
CLN5
|
Health Risk |
Pathogenic/Likely pathogenic |
Neuronal ceroid lipofuscinosis 5, Neuronal ceroid lipofuscinosis |
| RS764496155 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Inborn genetic diseases |
| RS764496230 |
DNMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory neuropathy-deafness-dementia syndrome, DNMT1-related disorder |
| RS76449634 |
RET
|
Health Risk |
Pathogenic |
Hirschsprung disease, susceptibility to |
| RS764497467 |
TBX1
|
Health Risk |
Conflicting classifications of pathogenicity |
DiGeorge syndrome, DiGeorge syndrome |
| RS764497513 |
CHAT
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial infantile myasthenia, Congenital myasthenic syndrome |
| RS764497524 |
GNB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Charcot-Marie-Tooth disease dominant intermediate F |
| RS764497659 |
PJVK
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 59, Autosomal recessive nonsyndromic hearing loss 59 |
| RS764498622 |
SETD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability-facial dysmorphism syndrome due to SETD5 haploinsufficiency, Inborn genetic diseases |
| RS764500338 |
IARS1
|
Health Risk |
Pathogenic |
Growth retardation, intellectual developmental disorder |
| RS764501022 |
ANKRD11
|
Health Risk |
Pathogenic |
ANKRD11-related disorder, Global developmental delay |
| RS764501046 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS764502383 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS764503373 |
ALMS1
|
Health Risk |
Likely pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS764506114 |
FBXO11
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764506321 |
NSD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764506732 |
TRIT1
|
Health Risk |
Likely pathogenic |
Combined oxidative phosphorylation deficiency 35, Combined oxidative phosphorylation deficiency 35 |
| RS764507012 |
CEP290
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Nephronophthisis |
| RS764507146 |
FANCD2
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group D2, Fanconi anemia |
| RS764507196 |
UNC13D
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 3, See cases |
| RS764507216 |
MYO3A
|
Health Risk |
Pathogenic |
— |
| RS764507532 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS764508785 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS764509489 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS764509824 |
DNAH11
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS764509990 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS764511452 |
DNAAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 13, Primary ciliary dyskinesia |
| RS76451285 |
F13A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Factor XIII, A subunit |
| RS764513998 |
ABCB4
|
Health Risk |
Likely pathogenic |
Cholestasis, intrahepatic |
| RS764514210 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS764514397 |
TTC21B
|
Health Risk |
Likely pathogenic |
Asphyxiating thoracic dystrophy 4, Nephronophthisis 12 |
| RS764514762 |
TG
|
Health Risk |
Pathogenic |
— |
| RS764514988 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS764515827 |
RASA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Capillary malformation-arteriovenous malformation syndrome, Cardiovascular phenotype |
| RS764517474 |
FAM161A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS764517475 |
DUOX2
|
Health Risk |
Likely pathogenic |
— |
| RS764518030 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHD7-related disorder, CHARGE syndrome |
| RS764518202 |
CRADD
|
Health Risk |
Pathogenic |
— |
| RS764519472 |
FANCF
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group F, Fanconi anemia complementation group F |
| RS764520289 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS764521226 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS764521300 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS764521635 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS764523123 |
KCNJ2
|
Health Risk |
Likely pathogenic |
— |
| RS764523283 |
ARL6
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 3, Retinitis pigmentosa 55 |
| RS764524104 |
ACADSB
|
Health Risk |
Likely pathogenic |
Deficiency of 2-methylbutyryl-CoA dehydrogenase, Deficiency of 2-methylbutyryl-CoA dehydrogenase |
| RS764524653 |
COL6A3
|
Health Risk |
Pathogenic |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS764524783 |
GRIA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndromic X-linked intellectual disability 94, Syndromic X-linked intellectual disability 94 |
| RS764524918 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS764525244 |
MAP3K1
|
Health Risk |
Conflicting classifications of pathogenicity |
46, XY sex reversal 6 |
| RS764526102 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS764526355 |
LIAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Lipoic acid synthetase deficiency, Inborn genetic diseases |
| RS764526789 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS764526847 |
SETBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764527357 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS764527438 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Kleefstra syndrome 1 |
| RS764527541 |
FKRP
|
Health Risk |
Conflicting classifications of pathogenicity |
Walker-Warburg congenital muscular dystrophy, Cardiovascular phenotype |
| RS764527706 |
APC
|
Health Risk |
Pathogenic |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS764527957 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS764529584 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS764529662 |
GALNS
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-IV-A |
| RS764529922 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764530848 |
CIROP
|
Health Risk |
Pathogenic |
Heterotaxy, visceral |
| RS764530865 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 4 |
| RS764531754 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Schwartz-Jampel syndrome, Lethal Kniest-like syndrome |
| RS76453279 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS764533757 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS764534524 |
CYP11B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of steroid 11-beta-monooxygenase, Glucocorticoid-remediable aldosteronism |
| RS764534989 |
FANCM
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS764536885 |
TULP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 15, Leber congenital amaurosis 15 |
| RS764538619 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS764538703 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS764538938 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764539113 |
CFH
|
Health Risk |
Conflicting classifications of pathogenicity |
CFH-Related Dense Deposit Disease / Membranoproliferative Glomerulonephritis Type II, Hemolytic uremic syndrome |
| RS764539241 |
OTUD6B
|
Health Risk |
Pathogenic |
— |
| RS764539267 |
GYS2
|
Health Risk |
Likely pathogenic |
Glycogen storage disorder due to hepatic glycogen synthase deficiency, Glycogen storage disorder due to hepatic glycogen synthase deficiency |
| RS764539989 |
FLNC
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypertrophic cardiomyopathy 26, Distal myopathy with posterior leg and anterior hand involvement |
| RS764540699 |
CDKL5;RS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 2 |
| RS764541059 |
COQ8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia due to ubiquinone deficiency, Autosomal recessive ataxia due to ubiquinone deficiency |
| RS764542651 |
ITGB4
|
Health Risk |
Likely pathogenic |
— |
| RS76454301 |
ALB
|
Health Risk |
Pathogenic |
Analbuminemia, Analbuminemia |
| RS764543553 |
VWF
|
Health Risk |
Likely pathogenic |
von Willebrand disease type 3, Hereditary von Willebrand disease |
| RS764543567 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS764544440 |
SNRNP200
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764544747 |
VPS13B
|
Health Risk |
Pathogenic/Likely pathogenic |
Cohen syndrome, Cohen syndrome |
| RS764544769 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Tibial muscular dystrophy |
| RS764544992 |
SLC45A2
|
Health Risk |
Likely pathogenic |
Oculocutaneous albinism type 4, SKIN/HAIR/EYE PIGMENTATION 5 |
| RS764546116 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS764546127 |
PROC
|
Health Risk |
Pathogenic |
Thrombophilia due to protein C deficiency, autosomal dominant |
| RS764546937 |
ASL
|
Health Risk |
Pathogenic/Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS764547244 |
RB1
|
Health Risk |
Pathogenic |
Hereditary retinoblastoma, Hereditary retinoblastoma |
| RS764548516 |
CLDN14
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 29, Autosomal recessive nonsyndromic hearing loss 29 |
| RS764548800 |
NPC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type C1 |
| RS764551108 |
CEP290
|
Health Risk |
Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS764551615 |
CAPN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS764551914 |
CCDC40
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS764552042 |
HEXB
|
Health Risk |
Pathogenic |
Sandhoff disease, Sandhoff disease |
| RS764552529 |
WT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Drash syndrome, Frasier syndrome |
| RS764552856 |
SATB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Chromosome 2q32-q33 deletion syndrome, Inborn genetic diseases |
| RS764554048 |
GRIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal dominant |