| RS764669598 |
MLC1
|
Health Risk |
Pathogenic |
Megalencephalic leukoencephalopathy with subcortical cysts 1, Megalencephalic leukoencephalopathy with subcortical cysts |
| RS764669712 |
TWNK
|
Health Risk |
Conflicting classifications of pathogenicity |
Perrault syndrome 5, Infantile onset spinocerebellar ataxia |
| RS764670084 |
GAA
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type II |
| RS764670510 |
SIX5
|
Health Risk |
Conflicting classifications of pathogenicity |
Branchiootorenal syndrome 2, Branchiootorenal syndrome 2 |
| RS764670582 |
GJA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Craniometaphyseal dysplasia, autosomal recessive |
| RS764670848 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Tibial muscular dystrophy |
| RS764670975 |
GRIA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndromic X-linked intellectual disability 94, Syndromic X-linked intellectual disability 94 |
| RS764671728 |
IGF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Growth delay due to insulin-like growth factor I resistance, Growth delay due to insulin-like growth factor I resistance |
| RS764672699 |
EYS
|
Health Risk |
Pathogenic |
— |
| RS764672734 |
PIGN
|
Health Risk |
Pathogenic |
Multiple congenital anomalies-hypotonia-seizures syndrome 1, Multiple congenital anomalies-hypotonia-seizures syndrome 1 |
| RS764674154 |
IRAK3
|
Health Risk |
Likely pathogenic |
— |
| RS764674361 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS764675280 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Inborn genetic diseases |
| RS764675404 |
KCNH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS764676359 |
ADGRV1
|
Health Risk |
Likely pathogenic |
— |
| RS764676548 |
PGAM2
|
Health Risk |
Pathogenic |
Glycogen storage disease type X, Glycogen storage disease type X |
| RS764679750 |
OBSCN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764681189 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS764684418 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS764684648 |
AR
|
Health Risk |
Likely pathogenic |
Male infertility, Male infertility |
| RS764685377 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764686162 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS764687326 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS764687344 |
BBS10
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 10 |
| RS764687744 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate E, Focal segmental glomerulosclerosis 5 |
| RS764688100 |
SLC13A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 25 |
| RS764689853 |
PACS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schuurs-Hoeijmakers syndrome, Inborn genetic diseases |
| RS764691105 |
GPD1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS764691345 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS764692110 |
CASQ2
|
Health Risk |
Pathogenic |
Catecholaminergic polymorphic ventricular tachycardia 2, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS764692193 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS764693182 |
SLC25A13
|
Health Risk |
Conflicting classifications of pathogenicity |
Citrullinemia, type II |
| RS764693395 |
GJB2
|
Health Risk |
Likely pathogenic |
— |
| RS764693725 |
COL5A1
|
Health Risk |
Pathogenic |
Ehlers-Danlos syndrome, classic type |
| RS764694597 |
NEK9
|
Health Risk |
Pathogenic |
— |
| RS764694805 |
DDC
|
Health Risk |
Pathogenic |
Deficiency of aromatic-L-amino-acid decarboxylase, Deficiency of aromatic-L-amino-acid decarboxylase |
| RS764696200 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, PIEZO1-related disorder |
| RS764696718 |
PKHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS764696852 |
SGCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Myoclonic dystonia 11, Myoclonic dystonia 11 |
| RS764697873 |
PCCB
|
Health Risk |
Pathogenic/Likely pathogenic |
Propionic acidemia, Propionic acidemia |
| RS764698152 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS764698262 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS764698870 |
GNE
|
Health Risk |
Pathogenic/Likely pathogenic |
GNE myopathy, Sialuria |
| RS764699819 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS764699954 |
PHKG2
|
Health Risk |
Pathogenic |
Glycogen storage disease IXc, Glycogen storage disease IXc |
| RS764700595 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS764700695 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Lung cancer |
| RS764701775 |
ALDOB
|
Health Risk |
Pathogenic |
Hereditary fructosuria, Hereditary fructosuria |
| RS764702321 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS764704217 |
DLD
|
Health Risk |
Pathogenic/Likely pathogenic |
Pyruvate dehydrogenase E3 deficiency, Pyruvate dehydrogenase E3 deficiency |
| RS764705223 |
CHD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy 94, Inborn genetic diseases |
| RS764705470 |
MYT1L
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal dominant 39 |
| RS764706394 |
HMGCS2
|
Health Risk |
Likely pathogenic |
3-hydroxy-3-methylglutaryl-CoA synthase deficiency, 3-hydroxy-3-methylglutaryl-CoA synthase deficiency |
| RS764707570 |
DDX54
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorders, Neurodevelopmental delay |
| RS764707646 |
ZFYVE26
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 15, Spastic paraplegia |
| RS764708878 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, Inborn genetic diseases |
| RS764710670 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764710968 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS764711007 |
F11
|
Health Risk |
Likely pathogenic |
Hereditary factor XI deficiency disease, Hereditary factor XI deficiency disease |
| RS764711165 |
DNM1L
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS76471260 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764712846 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Peutz-Jeghers syndrome |
| RS764713766 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS764714439 |
PRORP
|
Health Risk |
Pathogenic/Likely pathogenic |
6 conditions, Combined oxidative phosphorylation deficiency 54 |
| RS764715510 |
TRPV4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2C, Inborn genetic diseases |
| RS764717219 |
FIG4
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 4J, Charcot-Marie-Tooth disease type 4 |
| RS764718003 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
SCN4A-related non-dystrophic myotonia, Hyperkalemic periodic paralysis |
| RS764718355 |
COL9A3
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS764719093 |
CC2D2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome 9, COACH syndrome 1 |
| RS764720544 |
TTC19
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial complex III deficiency nuclear type 2, Autism |
| RS764720647 |
DYNC2H1
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS764722890 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764723506 |
SERPINH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type 10, Osteogenesis imperfecta type 10 |
| RS764723539 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CHARGE syndrome |
| RS764723654 |
CYP17A1
|
Health Risk |
Pathogenic |
Deficiency of steroid 17-alpha-monooxygenase, Deficiency of steroid 17-alpha-monooxygenase |
| RS764723711 |
POMT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2N, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS764724167 |
POMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1 |
| RS764724223 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant childhood-onset proximal spinal muscular atrophy without contractures, Intellectual disability |
| RS764724825 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS764725032 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS764725850 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS764727126 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS764728647 |
PDHA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyruvate dehydrogenase E1-alpha deficiency, Pyruvate dehydrogenase E1-alpha deficiency |
| RS764730223 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS764730691 |
GALNT3
|
Health Risk |
Pathogenic |
Tumoral calcinosis, hyperphosphatemic |
| RS764731332 |
XYLT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Thyroid cancer |
| RS764731559 |
PTPRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 104, Immunodeficiency 105 |
| RS764731848 |
MME
|
Health Risk |
Pathogenic |
— |
| RS764732335 |
TRIP12
|
Health Risk |
Conflicting classifications of pathogenicity |
Clark-Baraitser syndrome, Clark-Baraitser syndrome |
| RS764734266 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS764734415 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Hematuria |
| RS764734542 |
MAST1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764734665 |
NLRP7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764735889 |
TP53
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Li-Fraumeni syndrome |
| RS764736358 |
NYX
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764736571 |
TCF20
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764737103 |
ARSA
|
Health Risk |
Pathogenic |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS764738792 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS764738838 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764739106 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |