| RS764789266 |
GPT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764789298 |
DMD
|
Health Risk |
Pathogenic |
Abnormality of the musculature, Dilated cardiomyopathy 3B |
| RS764789542 |
NPC1
|
Health Risk |
Pathogenic |
Niemann-Pick disease, type C1 |
| RS764790770 |
CLN5
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis 5, Neuronal ceroid lipofuscinosis 5 |
| RS764791523 |
SPG7
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 7, Inborn genetic diseases |
| RS764791575 |
SLC12A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 34 |
| RS764792306 |
LOC130000832;SPAG1;VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 28, Primary ciliary dyskinesia |
| RS764792608 |
RMI1
|
Health Risk |
Likely pathogenic |
Colorectal cancer, Colorectal cancer |
| RS764792655 |
TYMP
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial DNA depletion syndrome 1, Mitochondrial DNA depletion syndrome 1 |
| RS764793347 |
NAGS
|
Health Risk |
Pathogenic |
Hyperammonemia, type III |
| RS764793623 |
CLCN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Epilepsy |
| RS764795457 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS764795648 |
RIPOR2
|
Health Risk |
Conflicting classifications of pathogenicity |
RIPOR2-related disorder, RIPOR2-related disorder |
| RS764797225 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS764797292 |
USH2A
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 39, Usher syndrome type 2A |
| RS764798214 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Cervical cancer |
| RS764798990 |
PRPF8
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS764801122 |
SLC12A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS764801717 |
ROBO3
|
Health Risk |
Pathogenic |
Gaze palsy, familial horizontal |
| RS764802895 |
GOSR2
|
Health Risk |
Pathogenic |
Progressive myoclonic epilepsy, Progressive myoclonic epilepsy |
| RS764804589 |
PDHX
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764804647 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, Donnai-Barrow syndrome |
| RS764804961 |
TNNT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1D, Cardiomyopathy |
| RS764805516 |
SPG11
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 11, Hereditary spastic paraplegia 11 |
| RS764805645 |
SLC22A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS764806176 |
CC2D2A
|
Health Risk |
Likely pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS764807072 |
DNAH8
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS764807307 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, RAI1-related disorder |
| RS764808511 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS764808552 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS764808999 |
PROC
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombophilia due to protein C deficiency, autosomal dominant |
| RS764809572 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Congenital contractural arachnodactyly |
| RS764811525 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764812763 |
DNAI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 9, Primary ciliary dyskinesia |
| RS764813110 |
DNAJB2
|
Health Risk |
Pathogenic |
Neuronopathy, distal hereditary motor |
| RS764813626 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS764814250 |
GLDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycine encephalopathy, Glycine encephalopathy 1 |
| RS764814296 |
LOC101928008;SBF2
|
Health Risk |
Likely pathogenic |
— |
| RS764815033 |
NAGLU
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-B |
| RS764816440 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS764816701 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
BAP1-related tumor predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS764816792 |
NTRK1
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease, Hereditary insensitivity to pain with anhidrosis |
| RS764816819 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS764817410 |
FANCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS764817484 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764817683 |
PKP2
|
Health Risk |
Pathogenic |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 9 |
| RS764819068 |
AIRE
|
Health Risk |
Pathogenic |
Polyglandular autoimmune syndrome, type 1 |
| RS764819788 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS764819816 |
SLC5A1
|
Health Risk |
Pathogenic |
Congenital glucose-galactose malabsorption, Congenital glucose-galactose malabsorption |
| RS764819935 |
ITGA2B
|
Health Risk |
Likely pathogenic |
Glanzmann thrombasthenia, Glanzmann thrombasthenia |
| RS764821044 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS764821435 |
TTN
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS764822052 |
KCNA2
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 1 |
| RS764823412 |
TELO2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764823441 |
PYGM
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease, type V |
| RS764823722 |
SPRED1
|
Health Risk |
Conflicting classifications of pathogenicity |
Legius syndrome, Legius syndrome |
| RS764823951 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS764824311 |
CDH23
|
Health Risk |
Pathogenic |
Retinal dystrophy, Usher syndrome type 1 |
| RS764825249 |
RLBP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS764825402 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group A |
| RS764826805 |
ALDOB
|
Health Risk |
Pathogenic |
Hereditary fructosuria, Hereditary fructosuria |
| RS764827027 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS764827256 |
EPHB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Capillary malformation-arteriovenous malformation 2, Capillary malformation-arteriovenous malformation 2 |
| RS764827921 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS764828665 |
LARS2
|
Health Risk |
Likely pathogenic |
Hydrops-lactic acidosis-sideroblastic anemia-multisystemic failure syndrome, Hydrops-lactic acidosis-sideroblastic anemia-multisystemic failure syndrome |
| RS764831063 |
DHDDS
|
Health Risk |
Likely pathogenic |
Congenital disorder of glycosylation, type Ibb |
| RS764831534 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS764831888 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS76483206 |
DYNC2LI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 6 with or without polydactyly, Short-rib thoracic dysplasia 6 with or without polydactyly |
| RS764832388 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly, normal intelligence and immunodeficiency |
| RS764832849 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764832852 |
FANCD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Fanconi anemia |
| RS764833435 |
GYS2
|
Health Risk |
Pathogenic/Likely pathogenic |
GYS2-related disorder, Glycogen storage disorder due to hepatic glycogen synthase deficiency |
| RS764833797 |
SLC12A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS764833865 |
SLC4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hemolytic anemia, Autosomal dominant distal renal tubular acidosis |
| RS764834875 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS764835191 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS764836394 |
FRAS1
|
Health Risk |
Pathogenic |
— |
| RS764837003 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS764838044 |
ATP8A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764838079 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Medulloblastoma, Gorlin syndrome |
| RS764838478 |
HOXD13
|
Health Risk |
Pathogenic |
Synpolydactyly type 1, Synpolydactyly type 1 |
| RS764839142 |
LAMA2
|
Health Risk |
Pathogenic |
Merosin deficient congenital muscular dystrophy, LAMA2-related muscular dystrophy |
| RS764839814 |
CACNA1A
|
Health Risk |
Pathogenic/Likely pathogenic |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS764839969 |
MYOM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS764840082 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Ovarian cancer |
| RS764840802 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS764841108 |
NLRP12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 2, Autoinflammatory syndrome |
| RS764841248 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS764841269 |
GSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Finnish type amyloidosis |
| RS764841861 |
STAG3
|
Health Risk |
Likely pathogenic |
Premature ovarian insufficiency, Female infertility |
| RS764842086 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS764842172 |
KRT14
|
Health Risk |
Pathogenic |
— |
| RS764842587 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS764842865 |
WFS1
|
Health Risk |
Likely risk allele |
Wolfram syndrome 1, Wolfram syndrome 1 |
| RS764843145 |
LYST
|
Health Risk |
Conflicting classifications of pathogenicity |
Chédiak-Higashi syndrome, Autoinflammatory syndrome |
| RS764843382 |
NEXMIF
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked intellectual disability, Cantagrel type |
| RS764845483 |
FAM161A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 28, Retinitis pigmentosa 28 |
| RS764846703 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS764847274 |
DHCR7
|
Health Risk |
Pathogenic |
Smith-Lemli-Opitz syndrome, Smith-Lemli-Opitz syndrome |