RMI1 Chromosome 9

RecQ mediated genome instability 1

2 variants 1 Drug Response 1 Health Risk

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What This Gene Does

Predicted to enable nucleotide binding activity. Involved in double-strand break repair via homologous recombination and resolution of DNA recombination intermediates. Located in nuclear body. Part of RecQ family helicase-topoisomerase III complex. [provided by Alliance of Genome Resources, Jul 2025]

Associated Conditions (2)

Olaparib response

Colorectal cancer

Key Variants

RS371202848

drug response

Olaparib response, Olaparib response

Drug Response

RS764792608

Likely pathogenic

Colorectal cancer, Colorectal cancer

Health Risk

All Variants (2)

RSID	Category	Clinical Significance	Conditions
RS371202848	Drug Response	drug response	Olaparib response, Olaparib response
RS764792608	Health Risk	Likely pathogenic	Colorectal cancer, Colorectal cancer