| RS764909409 |
GALE
|
Health Risk |
Conflicting classifications of pathogenicity |
UDPglucose-4-epimerase deficiency, Inborn genetic diseases |
| RS764910205 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS764911027 |
TBX1
|
Health Risk |
Conflicting classifications of pathogenicity |
DiGeorge syndrome, TBX1-related disorder |
| RS764911657 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS764912104 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Retinitis pigmentosa 80 |
| RS764913664 |
TRPV3
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated focal non-epidermolytic palmoplantar keratoderma, Inborn genetic diseases |
| RS764914308 |
AGL
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease type III, AGL-related disorder |
| RS764914973 |
EMC1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764915160 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764915190 |
BLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 11, Maturity-onset diabetes of the young type 11 |
| RS764916645 |
KDM5B
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS764917109 |
RFX7
|
Health Risk |
Pathogenic |
— |
| RS764917754 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS764918448 |
CNGA3
|
Health Risk |
Pathogenic |
Achromatopsia 2, Retinal dystrophy |
| RS764919087 |
MTHFD1
|
Health Risk |
Pathogenic |
— |
| RS764919230 |
GP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Bernard Soulier syndrome, Bernard Soulier syndrome |
| RS764919521 |
KCNU1
|
Health Risk |
Pathogenic |
Spermatogenic failure 79, Spermatogenic failure 79 |
| RS764919689 |
IDUA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis type 1, Mucopolysaccharidosis type 1 |
| RS764920626 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia, autosomal recessive |
| RS764920787 |
G6PC1
|
Health Risk |
Pathogenic |
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA, Glycogen storage disease due to glucose-6-phosphatase deficiency type IA |
| RS764921648 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS764921920 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS764921928 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764922350 |
SLC27A4
|
Health Risk |
Pathogenic |
Ichthyosis prematurity syndrome, Ichthyosis prematurity syndrome |
| RS76492282 |
PAX2
|
Health Risk |
Pathogenic |
Renal coloboma syndrome, Focal segmental glomerulosclerosis 7 |
| RS764924345 |
PEX7
|
Health Risk |
Pathogenic/Likely pathogenic |
Rhizomelic chondrodysplasia punctata type 1, Peroxisome biogenesis disorder 9B |
| RS764924872 |
SHANK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764925097 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS764925296 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS764925318 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 10, Arrhythmogenic right ventricular cardiomyopathy |
| RS764925691 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS764925739 |
ALS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile-onset ascending hereditary spastic paralysis, Hereditary spastic paraplegia |
| RS764926983 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Asphyxiating thoracic dystrophy 3 |
| RS764927038 |
HPS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hermansky-Pudlak syndrome, Hermansky-Pudlak syndrome 1 |
| RS764928653 |
SURF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease type 4K, See cases |
| RS764929170 |
SCP2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764929476 |
EP300
|
Health Risk |
Conflicting classifications of pathogenicity |
EP300-related disorder, Inborn genetic diseases |
| RS764929940 |
ASB10
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764930914 |
LMBRD1
|
Health Risk |
Likely pathogenic |
Cobalamin C disease, Cobalamin C disease |
| RS764931229 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1AA, Primary familial hypertrophic cardiomyopathy |
| RS764931697 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS764931883 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS764932308 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
WFS1-Related Spectrum Disorders, Autosomal dominant nonsyndromic hearing loss 6 |
| RS764935260 |
ANK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spherocytosis type 1, Hereditary spherocytosis type 1 |
| RS764935565 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS764935691 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764936506 |
UNC119
|
Health Risk |
Pathogenic/Likely pathogenic |
Macular dystrophy, Cone-rod dystrophy 24 |
| RS764936574 |
ELP1
|
Health Risk |
Pathogenic |
— |
| RS764936586 |
CLCN1
|
Health Risk |
Pathogenic |
— |
| RS764937305 |
TBXA2R
|
Health Risk |
Conflicting classifications of pathogenicity |
Bleeding disorder, platelet-type |
| RS764938319 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, Hirschsprung disease |
| RS764939265 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS764940495 |
PNPO
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyridoxal phosphate-responsive seizures, Pyridoxal phosphate-responsive seizures |
| RS764940559 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS764941172 |
LAMA5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764941200 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS764941621 |
TGFBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Loeys-Dietz syndrome 2 |
| RS764942 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome 1 |
| RS764942073 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS764942250 |
ACADM
|
Health Risk |
Conflicting classifications of pathogenicity |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, ACADM-related disorder |
| RS764942670 |
IGFBP7
|
Health Risk |
Pathogenic |
Familial retinal arterial macroaneurysm, Familial retinal arterial macroaneurysm |
| RS764944681 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, CREBBP-related disorder |
| RS764945940 |
CRYGD
|
Health Risk |
Pathogenic/Likely pathogenic |
Aculeiform cataract, Aculeiform cataract |
| RS764946227 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS764946729 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Retinitis pigmentosa 80 |
| RS764948348 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 17, MYH9-related disorder |
| RS764948774 |
MBD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764948792 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS764949139 |
CDH23
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome type 1D |
| RS764949536 |
TRPV4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2C, Brachyrachia (short spine dysplasia) |
| RS764949820 |
CYP19A1
|
Health Risk |
Likely pathogenic |
— |
| RS764949869 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS764950519 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinemic hypoglycemia, familial |
| RS764950557 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS764950910 |
MYH7B
|
Health Risk |
Pathogenic |
Hypertrophic cardiomyopathy 1, Hypertrophic cardiomyopathy 1 |
| RS764951157 |
TAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Tyrosinemia type II, Tyrosinemia type II |
| RS764951306 |
BIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, centronuclear |
| RS764951792 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal acantholytic epidermolysis bullosa, Woolly hair-skin fragility syndrome |
| RS764952788 |
CYLD
|
Health Risk |
Pathogenic |
Familial cylindromatosis, Familial cylindromatosis |
| RS764953041 |
AMPD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Pontocerebellar hypoplasia type 9 |
| RS764954235 |
GUCY2D
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis 1, Leber congenital amaurosis 1 |
| RS764954300 |
SKIC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Trichohepatoenteric syndrome 2, Trichohepatoenteric syndrome 2 |
| RS764955583 |
CAP2
|
Health Risk |
Pathogenic |
Cardiomyopathy, dilated |
| RS764955786 |
CARD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Severe combined immunodeficiency due to CARD11 deficiency |
| RS764956567 |
ATP8A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, ATP8A2-related disorder |
| RS764957750 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS764957919 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS764957976 |
PLA2G6
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile neuroaxonal dystrophy, PLA2G6-associated neurodegeneration |
| RS764958537 |
ABCC2
|
Health Risk |
Pathogenic |
— |
| RS764959117 |
FGFR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Craniosynostosis syndrome, Beare-Stevenson cutis gyrata syndrome |
| RS764959222 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Genitopatellar syndrome |
| RS764959343 |
TOP3A
|
Health Risk |
Likely pathogenic |
— |
| RS764959366 |
POP1
|
Health Risk |
Pathogenic |
— |
| RS764959531 |
TFG
|
Health Risk |
Likely pathogenic |
— |
| RS764959600 |
PLA2G6
|
Health Risk |
Pathogenic |
Infantile neuroaxonal dystrophy, Infantile neuroaxonal dystrophy |
| RS764959766 |
CACNA1G
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764960076 |
CHRNE
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome, Congenital myasthenic syndrome 4A |
| RS764960797 |
KRIT1
|
Health Risk |
Pathogenic |
Cerebral cavernous malformation, Cerebral cavernous malformation |
| RS764963626 |
CEP290
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Nephronophthisis |
| RS764963809 |
TRIO
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |