| RS765023388 |
SLC40A1
|
Health Risk |
Likely pathogenic |
Hemochromatosis type 4, Hemochromatosis type 4 |
| RS765025514 |
DNAAF5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765026901 |
CDH23
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 12 |
| RS765026950 |
MKS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS765027485 |
ATM
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS765027542 |
TSHR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hyperthyroidism due to mutations in TSH receptor, Hypothyroidism due to TSH receptor mutations |
| RS765027608 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa dystrophica, 7 conditions |
| RS765027886 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS765028361 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS765028553 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, SOS1-related disorder |
| RS765028638 |
NUP54
|
Health Risk |
Pathogenic |
Dystonia 37, early-onset |
| RS765028734 |
TNXB
|
Health Risk |
Pathogenic/Likely pathogenic |
Ehlers-Danlos syndrome due to tenascin-X deficiency, Vesicoureteral reflux 8 |
| RS765028767 |
POT1
|
Health Risk |
Pathogenic |
Tumor predisposition syndrome 3, Hereditary cancer-predisposing syndrome |
| RS765030404 |
PIK3CA
|
Health Risk |
Conflicting classifications of pathogenicity |
Cowden syndrome, Inborn genetic diseases |
| RS765030518 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS765031085 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS765032665 |
TRPM3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765033647 |
SRCAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765033981 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765034316 |
RINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765034336 |
COL7A1
|
Health Risk |
Pathogenic |
— |
| RS765034513 |
UNC13D
|
Health Risk |
Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis 3 |
| RS765035454 |
RP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 1, Retinitis pigmentosa 1 |
| RS765036417 |
SLC34A1
|
Health Risk |
Likely pathogenic |
— |
| RS765036679 |
FZD3
|
Health Risk |
Pathogenic |
Colorectal cancer, Colorectal cancer |
| RS765037444 |
NEK1
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 6 with or without polydactyly, Short-rib thoracic dysplasia 6 with or without polydactyly |
| RS765038815 |
ELP1
|
Health Risk |
Pathogenic |
— |
| RS765038828 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS765040215 |
SEMA3E
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, SEMA3E-related disorder |
| RS765043471 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Lymphangiomyomatosis |
| RS765043646 |
NPHP4
|
Health Risk |
Likely pathogenic |
Nephronophthisis 4, Nephronophthisis 4 |
| RS765043916 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS765043940 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinemic hypoglycemia, familial |
| RS765045050 |
BCKDHA
|
Health Risk |
Likely pathogenic |
Maple syrup urine disease, Maple syrup urine disease |
| RS765045862 |
SYN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, X-linked 1 |
| RS765046193 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765046399 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS765047440 |
DCLRE1C
|
Health Risk |
Pathogenic |
Severe combined immunodeficiency due to DCLRE1C deficiency, Athabaskan severe combined immunodeficiency |
| RS765047753 |
PCGF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765050364 |
WDR62
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 2, primary |
| RS765051582 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS765055351 |
ELANE
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Inborn genetic diseases |
| RS765057432 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS765059645 |
WDR4
|
Health Risk |
Pathogenic |
— |
| RS765059994 |
DICER1
|
Health Risk |
Likely pathogenic |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS765060096 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS765060373 |
ACAD9
|
Health Risk |
Pathogenic/Likely pathogenic |
Acyl-CoA dehydrogenase 9 deficiency, Acyl-CoA dehydrogenase 9 deficiency |
| RS765060493 |
IFIH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Singleton-Merten syndrome 1, Aicardi-Goutieres syndrome 7 |
| RS765060733 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS765061108 |
KIAA0753
|
Health Risk |
Likely pathogenic |
— |
| RS765061205 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Bloom syndrome |
| RS765061513 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS765061840 |
SPG11
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease axonal type 2X, Hereditary spastic paraplegia 11 |
| RS765062693 |
UPB1
|
Health Risk |
Likely pathogenic |
Deficiency of beta-ureidopropionase, Deficiency of beta-ureidopropionase |
| RS765063091 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Febrile seizures |
| RS765063151 |
LRAT
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS765063390 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS765063539 |
ETFDH
|
Health Risk |
Pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS765064597 |
ABCC2
|
Health Risk |
Likely pathogenic |
— |
| RS765064661 |
KCNJ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial fibrillation, familial |
| RS765064954 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS765064980 |
SPI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Agammaglobulinemia 10, autosomal dominant |
| RS765065009 |
POGLUT1
|
Health Risk |
Pathogenic |
— |
| RS765066118 |
PCDH19
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 9 |
| RS765067013 |
OTOF
|
Health Risk |
Pathogenic |
— |
| RS765067070 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765067237 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 11, Cardiomyopathy |
| RS765067395 |
EPHB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS765068619 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary familial hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS765068810 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS76506918 |
MFSD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 7, Late-infantile neuronal ceroid lipofuscinosis |
| RS765069812 |
FECH
|
Health Risk |
Conflicting classifications of pathogenicity |
Protoporphyria, erythropoietic |
| RS765069962 |
ATP1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765070028 |
ABCB11
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765070399 |
GRK1
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Oguchi disease-2 |
| RS765070623 |
FOXP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability-severe speech delay-mild dysmorphism syndrome, Intellectual disability |
| RS765070743 |
AGA
|
Health Risk |
Pathogenic |
Aspartylglucosaminuria, Aspartylglucosaminuria |
| RS765070830 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, RASopathy |
| RS765072095 |
GPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilms tumor 1, Simpson-Golabi-Behmel syndrome type 1 |
| RS765072583 |
CC2D2A
|
Health Risk |
Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS765072736 |
GRIA2
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with language impairment and behavioral abnormalities, Neurodevelopmental disorder with language impairment and behavioral abnormalities |
| RS765075310 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS765075763 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS765076649 |
EVC2
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS765077011 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 8 |
| RS765077104 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS765079080 |
COL5A1
|
Health Risk |
Pathogenic |
Ehlers-Danlos syndrome, classic type |
| RS765079746 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS765079866 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS765080315 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS765080766 |
CHEK2
|
Health Risk |
Likely pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS76508383 |
COQ9
|
Health Risk |
Conflicting classifications of pathogenicity |
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, COQ9-related disorder |
| RS765084318 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS765084436 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765085056 |
CLRN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome, Usher syndrome |
| RS765086319 |
FA2H
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Hereditary spastic paraplegia |
| RS765088174 |
RARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pontocerebellar hypoplasia type 6, Pontoneocerebellar hypoplasia |
| RS765088669 |
GALNT12
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765089126 |
SLC1A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome, Spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome |
| RS765089689 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |