| RS765145201 |
NGLY1
|
Health Risk |
Pathogenic |
Congenital disorder of deglycosylation, Congenital disorder of deglycosylation |
| RS765148928 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS765149006 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS765149078 |
MCCC1
|
Health Risk |
Pathogenic |
3-methylcrotonyl-CoA carboxylase 1 deficiency, 3-methylcrotonyl-CoA carboxylase 1 deficiency |
| RS765149569 |
ALPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypophosphatasia, Adult hypophosphatasia |
| RS765149885 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS765150956 |
FANCG
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group G, Fanconi anemia complementation group G |
| RS765151419 |
UNG
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyper-IgM syndrome type 5, Hyper-IgM syndrome type 5 |
| RS765151646 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS765154144 |
DHCR7
|
Health Risk |
Likely pathogenic |
Smith-Lemli-Opitz syndrome, Smith-Lemli-Opitz syndrome |
| RS765154255 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, arthrochalasia type |
| RS765154628 |
SNIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765155697 |
CDC14A
|
Health Risk |
Likely pathogenic |
Rare genetic deafness, Rare genetic deafness |
| RS765156027 |
LEMD3
|
Health Risk |
Pathogenic |
— |
| RS765156052 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS765156550 |
PLA2G6
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Infantile neuroaxonal dystrophy |
| RS765156859 |
SMAD9
|
Health Risk |
Likely pathogenic |
Pulmonary hypertension, primary |
| RS765157365 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS765157752 |
CLN3
|
Health Risk |
Likely pathogenic |
— |
| RS765158675 |
ICOS
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS765160098 |
PRKDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to DNA-PKcs deficiency, Severe combined immunodeficiency due to DNA-PKcs deficiency |
| RS765160493 |
HOGA1
|
Health Risk |
Likely pathogenic |
Primary hyperoxaluria type 3, Primary hyperoxaluria type 3 |
| RS765161206 |
CPT1A
|
Health Risk |
Pathogenic |
Carnitine palmitoyl transferase 1A deficiency, Carnitine palmitoyl transferase 1A deficiency |
| RS765163533 |
LAMC3
|
Health Risk |
Pathogenic |
— |
| RS765163542 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, VPS13B-related disorder |
| RS765164994 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Cardiovascular phenotype |
| RS765166082 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS765166428 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal Kniest-like syndrome, Lethal Kniest-like syndrome |
| RS765166981 |
ITGA8
|
Health Risk |
Likely pathogenic |
Renal hypodysplasia/aplasia 1, Renal hypodysplasia/aplasia 1 |
| RS765168342 |
NTHL1
|
Health Risk |
Pathogenic |
Familial adenomatous polyposis 3, Familial adenomatous polyposis 3 |
| RS765169367 |
KCNQ1
|
Health Risk |
Pathogenic |
Long QT syndrome, Long QT syndrome |
| RS765169755 |
HPS3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hermansky-Pudlak syndrome 3, Hermansky-Pudlak syndrome 3 |
| RS765170329 |
AFG2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome, Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome |
| RS765170454 |
ACADM
|
Health Risk |
Conflicting classifications of pathogenicity |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Inborn genetic diseases |
| RS765170704 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS765172300 |
TCF20
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765173966 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS765174527 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS765175059 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS765175526 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 7 |
| RS765175595 |
SLC12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bartter disease type 1, Bartter disease type 1 |
| RS765176007 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperkalemic periodic paralysis, 7 conditions |
| RS765177174 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS765178095 |
ADGRV1
|
Health Risk |
Pathogenic |
— |
| RS765178830 |
FGD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765178985 |
SPG7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 7, Hereditary spastic paraplegia 7 |
| RS765180149 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS765181270 |
ABL1
|
Health Risk |
Conflicting classifications of pathogenicity |
ABL1-related disorder, ABL1-related disorder |
| RS765181341 |
CLCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myotonia, autosomal dominant form |
| RS765181893 |
TGM6
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 35, Spinocerebellar ataxia type 35 |
| RS765182070 |
BRWD3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765185645 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS765185884 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765186480 |
COPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoimmune interstitial lung disease-arthritis syndrome, Autoimmune interstitial lung disease-arthritis syndrome |
| RS765187060 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS765187664 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Spastic paraplegia |
| RS765188969 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Idiopathic generalized epilepsy |
| RS765189194 |
ALPK3
|
Health Risk |
Pathogenic |
— |
| RS765189771 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS765189933 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Retinitis pigmentosa |
| RS765190704 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS765190948 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765191836 |
SRD5A3
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Congenital disorder of glycosylation |
| RS765192701 |
SLC25A13
|
Health Risk |
Conflicting classifications of pathogenicity |
Citrin deficiency, SLC25A13-related disorder |
| RS765192739 |
GJA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, GJA1-related disorder |
| RS765193793 |
SYNGAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 5 |
| RS765195368 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 9 |
| RS765195369 |
MYO15A
|
Health Risk |
Pathogenic |
— |
| RS765195534 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS765195623 |
PKD1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
Heterotaxy, visceral |
| RS765196085 |
APC
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS765196598 |
PCYT1A
|
Health Risk |
Likely pathogenic |
— |
| RS765197501 |
RP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS765197819 |
SLC26A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 4, Pendred syndrome |
| RS765198174 |
HMGCL
|
Health Risk |
Likely pathogenic |
Deficiency of hydroxymethylglutaryl-CoA lyase, Deficiency of hydroxymethylglutaryl-CoA lyase |
| RS765198326 |
PKD1L1
|
Health Risk |
Likely pathogenic |
— |
| RS76519865 |
EFTUD2
|
Health Risk |
Pathogenic |
— |
| RS765198848 |
MYD88
|
Health Risk |
Pathogenic |
Pyogenic bacterial infections due to MyD88 deficiency, Pyogenic bacterial infections due to MyD88 deficiency |
| RS765199175 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 4, Cardiovascular phenotype |
| RS765199264 |
TCTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS765201028 |
INVS
|
Health Risk |
Pathogenic |
Nephronophthisis, Nephronophthisis |
| RS765201464 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS765202218 |
PDE6C
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone dystrophy 4, Achromatopsia |
| RS765203751 |
GRIP1
|
Health Risk |
Pathogenic |
— |
| RS765204502 |
TBX5
|
Health Risk |
Pathogenic |
Holt-Oram syndrome, Aortic valve disease 2 |
| RS765204887 |
GBE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type IV |
| RS765205164 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS765205440 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, KBG syndrome |
| RS765205515 |
MTPAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765205871 |
MFAP5
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS765206082 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765207227 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS765207911 |
SERPINF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, SERPINF1-related disorder |
| RS765209037 |
PKHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS765211108 |
NGLY1
|
Health Risk |
Pathogenic |
Intellectual disability, Peripheral neuropathy |
| RS765213828 |
HADHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency, Inborn genetic diseases |
| RS765214404 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS765216544 |
IL37
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765216874 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS765217611 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |