| RS765277720 |
CEP164
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 15, Nephronophthisis 15 |
| RS765278464 |
PRF1
|
Health Risk |
Likely pathogenic |
Aplastic anemia, Familial hemophagocytic lymphohistiocytosis 2 |
| RS765279896 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS765281145 |
FITM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Siddiqi syndrome, Siddiqi syndrome |
| RS765281937 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS765282250 |
MAP3K1
|
Health Risk |
Conflicting classifications of pathogenicity |
46, XY sex reversal 6 |
| RS765282375 |
CC2D1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765283048 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 2, Cardiomyopathy |
| RS765284825 |
MMUT
|
Health Risk |
Pathogenic/Likely pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic acidemia |
| RS765285682 |
DNAI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 9 |
| RS765287425 |
IL7R
|
Health Risk |
Pathogenic |
Immunodeficiency 104, Immunodeficiency 104 |
| RS765287559 |
MYL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 10, Cardiomyopathy |
| RS765287715 |
STX11
|
Health Risk |
Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 4, Familial hemophagocytic lymphohistiocytosis 4 |
| RS765288116 |
MTR
|
Health Risk |
Likely pathogenic |
Methylcobalamin deficiency type cblG, Methylcobalamin deficiency type cblG |
| RS765289515 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS765290152 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS765290711 |
LRP5
|
Health Risk |
Likely pathogenic |
8 conditions, LRP5-related disorder |
| RS765291607 |
FRAS1
|
Health Risk |
Likely pathogenic |
Fraser syndrome 1, Fraser syndrome 1 |
| RS765292152 |
CAPN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS765293412 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Usher syndrome type 2A |
| RS765293859 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS765294324 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765294583 |
AIP
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS765296153 |
NEK1
|
Health Risk |
Likely pathogenic |
Short-rib thoracic dysplasia 6 with or without polydactyly, Short-rib thoracic dysplasia 6 with or without polydactyly |
| RS765296989 |
PDE6C
|
Health Risk |
Pathogenic |
Achromatopsia, Achromatopsia |
| RS765297527 |
LRBA
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to LRBA deficiency, Combined immunodeficiency due to LRBA deficiency |
| RS765298019 |
RAG2
|
Health Risk |
Pathogenic |
Inborn error of immunity, Severe combined immunodeficiency |
| RS765298217 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS765298573 |
AIFM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation deficiency, Charcot-Marie-Tooth Neuropathy X |
| RS765299653 |
CPAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 6, primary |
| RS765300713 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS765301342 |
CUBN
|
Health Risk |
Pathogenic/Likely pathogenic |
Imerslund-Grasbeck syndrome, CUBN-related disorder |
| RS765301554 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS765302278 |
VPS13B
|
Health Risk |
Pathogenic |
Cohen syndrome, Cohen syndrome |
| RS765303299 |
ITK
|
Health Risk |
Conflicting classifications of pathogenicity |
Lymphoproliferative syndrome 1, Lymphoproliferative syndrome 1 |
| RS765304225 |
ABCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765304898 |
RAD51C
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group O, Hereditary cancer-predisposing syndrome |
| RS765305472 |
CERKL
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 26, Retinitis pigmentosa 26 |
| RS765305996 |
ECEL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Arthrogryposis multiplex congenita |
| RS765306132 |
ESAM
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder with intracranial hemorrhage, seizures |
| RS76530653 |
PEX10
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 6A (Zellweger), Peroxisome biogenesis disorder |
| RS765306552 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS765307374 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS765307463 |
PNPLA6
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 39, Inborn genetic diseases |
| RS765308785 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765309737 |
PPP5C
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765309844 |
NFU1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple mitochondrial dysfunctions syndrome 1, Inborn genetic diseases |
| RS765310894 |
MPI
|
Health Risk |
Pathogenic/Likely pathogenic |
MPI-congenital disorder of glycosylation, MPI-congenital disorder of glycosylation |
| RS765310938 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS765311079 |
SLC27A4
|
Health Risk |
Likely pathogenic |
Ichthyosis prematurity syndrome, Ichthyosis prematurity syndrome |
| RS765311365 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765312755 |
MYH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 14 |
| RS765313977 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome 5 |
| RS765314309 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 1 |
| RS765314472 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS765315726 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Inborn genetic diseases |
| RS765316175 |
TTN
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Dilated cardiomyopathy 1G |
| RS765317127 |
LIG4
|
Health Risk |
Pathogenic |
DNA ligase IV deficiency, LIG4-related disorder |
| RS765317927 |
CEP152
|
Health Risk |
Pathogenic |
— |
| RS765318603 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS765320441 |
MYO5A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765320988 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS765322804 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Type 2 diabetes mellitus, Cataract 41 |
| RS765323349 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS765323914 |
CLN5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 5, Neuronal ceroid lipofuscinosis |
| RS765323986 |
TSEN54
|
Health Risk |
Likely pathogenic |
— |
| RS765324128 |
FREM2
|
Health Risk |
Pathogenic/Likely pathogenic |
Isolated cryptophthalmia, Fraser syndrome 2 |
| RS765325621 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765325642 |
PACS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schuurs-Hoeijmakers syndrome, Intellectual disability |
| RS765325777 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Rhabdoid tumor predisposition syndrome 2 |
| RS765325906 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS765326959 |
PUS7
|
Health Risk |
Likely pathogenic |
Intellectual developmental disorder with abnormal behavior, microcephaly |
| RS765327224 |
INPP5E
|
Health Risk |
Conflicting classifications of pathogenicity |
Rod-cone dystrophy, Joubert syndrome |
| RS765327583 |
EPG5
|
Health Risk |
Likely pathogenic |
— |
| RS765327656 |
TGFB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Diaphyseal dysplasia, Cystic fibrosis |
| RS765327792 |
ASXL1
|
Health Risk |
Likely pathogenic |
Bohring-Opitz syndrome, Bohring-Opitz syndrome |
| RS765328255 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS765328414 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS765329261 |
TYR
|
Health Risk |
Pathogenic |
Oculocutaneous albinism type 1A, Oculocutaneous albinism type 1A |
| RS765330837 |
TCF3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765330886 |
KANK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebral palsy, spastic quadriplegic |
| RS765332596 |
AP5Z1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 48, Hereditary spastic paraplegia 48 |
| RS765332671 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS765332910 |
PHKB
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease IXb, Glycogen storage disease IXb |
| RS765333778 |
BEST1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS765335418 |
HSD3B2
|
Health Risk |
Pathogenic |
3 beta-Hydroxysteroid dehydrogenase deficiency, 3 beta-Hydroxysteroid dehydrogenase deficiency |
| RS765335850 |
TAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class I deficiency, MHC class I deficiency |
| RS765336013 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Benign familial hematuria, Autosomal dominant Alport syndrome |
| RS765336852 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Tuberous sclerosis syndrome |
| RS765336893 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS765336896 |
SCNN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Liddle syndrome 1, Bronchiectasis with or without elevated sweat chloride 1 |
| RS765338121 |
ASS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Citrullinemia type I, Citrullinemia |
| RS765339120 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS765339802 |
POLG
|
Health Risk |
Likely pathogenic |
Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy |
| RS765339835 |
WWOX
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 28 |
| RS765340947 |
CAD
|
Health Risk |
Pathogenic |
— |
| RS765341703 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS765342744 |
ETFA
|
Health Risk |
Pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS765343914 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS765344006 |
FBXO7
|
Health Risk |
Conflicting classifications of pathogenicity |
Parkinsonian-pyramidal syndrome, Parkinsonian-pyramidal syndrome |