| RS765448750 |
TLE6
|
Health Risk |
Pathogenic |
— |
| RS765448811 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS765449173 |
PIGV
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperphosphatasia with intellectual disability syndrome 1, Inborn genetic diseases |
| RS765449212 |
GDF1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765450816 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Ehlers-Danlos syndrome |
| RS765451882 |
WDR62
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765454943 |
DYNC2H1
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS765455172 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1, CDH23-related disorder |
| RS765455455 |
PTPN11
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome and Noonan-related syndrome, RASopathy |
| RS765455808 |
FRAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 1, Fraser syndrome 1 |
| RS765457523 |
CPLANE1
|
Health Risk |
Conflicting classifications of pathogenicity |
CPLANE1-related disorder, Orofaciodigital syndrome type 6 |
| RS765457704 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS765458125 |
ALPL
|
Health Risk |
Pathogenic/Likely pathogenic |
Adult hypophosphatasia, Hypophosphatasia |
| RS765459582 |
GJA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculodentodigital dysplasia, Hypoplastic left heart syndrome 1 |
| RS765459820 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765460065 |
NPHP4
|
Health Risk |
Likely pathogenic |
Nephronophthisis, Nephronophthisis |
| RS765461259 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Alstrom syndrome |
| RS765461729 |
NSUN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765463082 |
GUCY2D
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis 1, Cone-rod dystrophy 6 |
| RS765463274 |
FANCI
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS765463636 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS765464461 |
FNIP1
|
Health Risk |
Likely pathogenic |
Immunodeficiency 93 and hypertrophic cardiomyopathy, Immunodeficiency 93 and hypertrophic cardiomyopathy |
| RS765464485 |
PRDM5
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS765468034 |
MYO15A
|
Health Risk |
Pathogenic |
Rare genetic deafness, Autosomal recessive nonsyndromic hearing loss 3 |
| RS765468063 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS765468519 |
PCCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Propionic acidemia, Propionic acidemia |
| RS765468645 |
TMEM67
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Generalized hypotonia |
| RS765471424 |
AGK
|
Health Risk |
Pathogenic |
Sengers syndrome, Cataract 38 |
| RS765472301 |
SH3PXD2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765472726 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, 6 conditions |
| RS765473119 |
LCA5
|
Health Risk |
Pathogenic |
Leber congenital amaurosis, Leber congenital amaurosis |
| RS765473830 |
IDH3A
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 90, Retinitis pigmentosa 90 |
| RS765474118 |
GP1BA
|
Health Risk |
Pathogenic |
Pseudo von Willebrand disease, Pseudo von Willebrand disease |
| RS765475926 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome |
| RS765475941 |
HMGCL
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of hydroxymethylglutaryl-CoA lyase, Deficiency of hydroxymethylglutaryl-CoA lyase |
| RS765476443 |
KDM1A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765476509 |
CALR
|
Health Risk |
Pathogenic |
Thrombocythemia 1, Primary myelofibrosis |
| RS765476521 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS765476745 |
USH2A
|
Health Risk |
Pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS765477124 |
NTRK1
|
Health Risk |
Likely pathogenic |
Hereditary insensitivity to pain with anhidrosis, Hereditary insensitivity to pain with anhidrosis |
| RS765477482 |
SPG11
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 11, Hereditary spastic paraplegia 11 |
| RS765478068 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS765478662 |
FGF23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypophosphatemic rickets, Tumoral calcinosis |
| RS765478968 |
GARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS765478990 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group A, Fanconi anemia complementation group A |
| RS765480069 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765480571 |
COL7A1
|
Health Risk |
Likely pathogenic |
Recessive dystrophic epidermolysis bullosa, Generalized dominant dystrophic epidermolysis bullosa |
| RS765483163 |
CEP290
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome, Nephronophthisis |
| RS765483435 |
TUBA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
TUBA1A-related disorder, TUBA1A-related disorder |
| RS765483709 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765483979 |
MYORG
|
Health Risk |
Likely pathogenic |
Basal ganglia calcification, idiopathic |
| RS765484171 |
RAD50
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Nijmegen breakage syndrome-like disorder |
| RS765484849 |
CPS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital hyperammonemia, type I |
| RS765486614 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS765487110 |
FAM161A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS765487627 |
GLRX5
|
Health Risk |
Pathogenic |
Sideroblastic anemia 3, Sideroblastic anemia 3 |
| RS765487816 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS765489269 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS765489754 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS765490369 |
MLC1
|
Health Risk |
Pathogenic |
— |
| RS765492483 |
NGLY1
|
Health Risk |
Likely pathogenic |
Congenital disorder of deglycosylation 1, Congenital disorder of deglycosylation 1 |
| RS765493144 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS765493484 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS765493709 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS765494437 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS765496324 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765496350 |
LSS
|
Health Risk |
Pathogenic |
Alopecia-intellectual disability syndrome 4, Alopecia-intellectual disability syndrome 4 |
| RS76549675 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Inborn genetic diseases |
| RS765497074 |
GPD1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS765498367 |
AMMECR1
|
Health Risk |
Likely pathogenic |
Midface hypoplasia, hearing impairment |
| RS765498698 |
SCN3A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765499763 |
GSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Finnish type amyloidosis |
| RS765499904 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS765501841 |
CUL3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765502145 |
SLC34A3
|
Health Risk |
Likely pathogenic |
— |
| RS765502530 |
CCBE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hennekam lymphangiectasia-lymphedema syndrome 1, Hennekam lymphangiectasia-lymphedema syndrome 1 |
| RS765502638 |
SLC5A1
|
Health Risk |
Pathogenic |
Congenital glucose-galactose malabsorption, Congenital glucose-galactose malabsorption |
| RS765503214 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
6 conditions, Dilated cardiomyopathy 1G |
| RS765503809 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS765503816 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS765506021 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, Hereditary spastic paraplegia |
| RS765506121 |
ANKRD26
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombocytopenia 2, Inborn genetic diseases |
| RS765506701 |
IL10RB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inflammatory bowel disease 25, Inborn genetic diseases |
| RS765507339 |
TRRAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765507796 |
C9
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765508670 |
ALPK3
|
Health Risk |
Pathogenic |
— |
| RS765511273 |
MYH3
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS765511300 |
ALAS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765511963 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Norman-Roberts syndrome |
| RS765512351 |
CYP27A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cholestanol storage disease, CYP27A1-related disorder |
| RS765512476 |
TTN;TTN-AS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Dilated cardiomyopathy 1G |
| RS765512575 |
INS
|
Health Risk |
Conflicting classifications of pathogenicity |
Transient Neonatal Diabetes, Dominant/Recessive |
| RS765513105 |
WDR35
|
Health Risk |
Pathogenic/Likely pathogenic |
Short-rib thoracic dysplasia 6 with or without polydactyly, Cranioectodermal dysplasia 2 |
| RS765514069 |
RUSC2
|
Health Risk |
Likely pathogenic |
Intellectual disability, autosomal recessive 61 |
| RS765514910 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 4, Senior-Loken syndrome 4 |
| RS765514964 |
SMARCB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, SMARCB1-related disorder |
| RS765515764 |
DYNC2H1
|
Health Risk |
Likely pathogenic |
DYNC2H1-related disorder, DYNC2H1-related disorder |
| RS765517032 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS765517862 |
EFEMP1
|
Health Risk |
Pathogenic |
14 conditions, Cutis laxa |
| RS765518889 |
FECH
|
Health Risk |
Likely pathogenic |
Protoporphyria, erythropoietic |