| RS765519281 |
EDAR
|
Health Risk |
Likely pathogenic |
— |
| RS765520147 |
LIG4
|
Health Risk |
Conflicting classifications of pathogenicity |
DNA ligase IV deficiency, DNA ligase IV deficiency |
| RS765520187 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS765520656 |
DNAH5
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765522088 |
P3H1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type 8, Osteogenesis imperfecta type 8 |
| RS765522418 |
ABCG8
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765523959 |
CACNA1E
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765524239 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS765525417 |
TFR2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary hemochromatosis, Hemochromatosis type 3 |
| RS765525964 |
TFR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary hemochromatosis, Hemochromatosis type 3 |
| RS765526 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS765527118 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS765527121 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, COL6A3-related disorder |
| RS765527234 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia type 4, Hereditary cancer-predisposing syndrome |
| RS765527607 |
TAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class I deficiency, MHC class I deficiency |
| RS765527687 |
FAH
|
Health Risk |
Pathogenic/Likely pathogenic |
Tyrosinemia type I, Tyrosinemia type I |
| RS765527736 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS765529429 |
MYH2
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS765529435 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa dystrophica, Recessive dystrophic epidermolysis bullosa |
| RS765529707 |
CHKA
|
Health Risk |
Likely pathogenic |
Microcephaly, Severe intellectual disability |
| RS765530046 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS765530283 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765530357 |
ASPM
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS765531464 |
ABCA7
|
Health Risk |
Pathogenic |
ABCA7-related disorder, ABCA7-related disorder |
| RS765531556 |
ADAMTS17
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani 4 syndrome, recessive |
| RS765531651 |
CACNA1A
|
Health Risk |
Pathogenic |
CACNA1A-related complex neurodevelopmental disorder, CACNA1A-related complex neurodevelopmental disorder |
| RS765532123 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS765533675 |
NPHP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 3, Renal-hepatic-pancreatic dysplasia 1 |
| RS765534006 |
NPHS1
|
Health Risk |
Likely pathogenic |
— |
| RS765535147 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Cardiovascular phenotype |
| RS765535822 |
TUBGCP6
|
Health Risk |
Pathogenic |
— |
| RS765536137 |
CRB1
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 8, Retinitis pigmentosa 12 |
| RS765536334 |
TMEM67
|
Health Risk |
Likely pathogenic |
— |
| RS765536522 |
CSF3R
|
Health Risk |
Pathogenic |
Autosomal recessive severe congenital neutropenia due to CSF3R deficiency, CSF3R-related disorder |
| RS765537459 |
EPRS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Leukodystrophy, hypomyelinating |
| RS765539314 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS765540111 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 2 |
| RS765541438 |
MAGI2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765542839 |
PHGDH
|
Health Risk |
Conflicting classifications of pathogenicity |
PHGDH deficiency, PHGDH deficiency |
| RS765542916 |
CDKN1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Beckwith-Wiedemann syndrome, IMAGe syndrome |
| RS765543886 |
BCKDHA
|
Health Risk |
Pathogenic/Likely pathogenic |
Maple syrup urine disease, Maple syrup urine disease type 1A |
| RS765544171 |
EIF2AK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolcott-Rallison dysplasia, Wolcott-Rallison dysplasia |
| RS765544509 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS765544833 |
WWOX
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 28 |
| RS76554633 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, CFTR-related disorder |
| RS765547005 |
MMAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylmalonic aciduria, cblB type |
| RS765547422 |
HSD3B2
|
Health Risk |
Pathogenic |
Congenital adrenal hyperplasia, Congenital adrenal hyperplasia |
| RS765548056 |
MCM3AP
|
Health Risk |
Pathogenic |
— |
| RS765548101 |
CCM2
|
Health Risk |
Pathogenic |
Cavernous hemangioma, Cerebral cavernous malformation 2 |
| RS765548407 |
RNF43
|
Health Risk |
Conflicting classifications of pathogenicity |
Sessile serrated polyposis cancer syndrome, Sessile serrated polyposis cancer syndrome |
| RS765548847 |
MTO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial hypertrophic cardiomyopathy with lactic acidosis due to MTO1 deficiency, Mitochondrial hypertrophic cardiomyopathy with lactic acidosis due to MTO1 deficiency |
| RS765548922 |
MYOM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS765549411 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS765549490 |
CFTR
|
Health Risk |
Likely pathogenic |
Cystic fibrosis, Cystic fibrosis |
| RS765550303 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS765550592 |
FRAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 1, FRAS1-related disorder |
| RS765551089 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS765551290 |
LEPR
|
Health Risk |
Pathogenic |
— |
| RS765551897 |
FANCC
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia complementation group C |
| RS765552403 |
EMC10
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with dysmorphic facies and variable seizures, Inborn genetic diseases |
| RS765552494 |
PAH
|
Health Risk |
Pathogenic |
Phenylketonuria, Phenylketonuria |
| RS765553310 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS765553799 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS765554006 |
ERCC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group G |
| RS765554137 |
ANKZF1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765555186 |
CLCN2
|
Health Risk |
Likely pathogenic |
— |
| RS765556063 |
MUSK
|
Health Risk |
Pathogenic |
Fetal akinesia deformation sequence 1, Congenital myasthenic syndrome 9 |
| RS765556214 |
GRIA4
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with or without seizures and gait abnormalities, Intellectual disability |
| RS765556647 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS765556817 |
ACAN
|
Health Risk |
Pathogenic/Likely pathogenic |
Short stature and advanced bone age, with or without early-onset osteoarthritis and/or osteochondritis dissecans |
| RS765557053 |
TBL1XR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pierpont syndrome, Gastric cancer |
| RS765557765 |
SPG11
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 11, Hereditary spastic paraplegia 11 |
| RS765557914 |
CACNA1A
|
Health Risk |
Pathogenic |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS765558281 |
ARHGAP24
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765561257 |
ALDH5A1
|
Health Risk |
Pathogenic |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS765561672 |
BBS10
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome 10, Bardet-Biedl syndrome 10 |
| RS765561928 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765561953 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765562062 |
NLRP12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 2, Autoimmune interstitial lung disease-arthritis syndrome |
| RS765563111 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS765563320 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated macular dystrophy, Isolated macular dystrophy |
| RS765563414 |
MACF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765563471 |
IDUA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis type 1, Inborn genetic diseases |
| RS765566169 |
DIDO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765566328 |
MED13L
|
Health Risk |
Conflicting classifications of pathogenicity |
Dextro-looped transposition of the great arteries, Dextro-looped transposition of the great arteries |
| RS765566930 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal dominant 2 |
| RS765569628 |
TSHR
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hyperthyroidism |
| RS765569689 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS765569983 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Inborn genetic diseases |
| RS765570396 |
ABCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dubin-Johnson syndrome, ABCC2-related disorder |
| RS765570412 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS765570755 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS765571333 |
PKD1L1
|
Health Risk |
Pathogenic |
— |
| RS765571443 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765571574 |
BBS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, BBS1-related disorder |
| RS765572951 |
ELP1
|
Health Risk |
Likely pathogenic |
Familial dysautonomia, Familial dysautonomia |
| RS765574129 |
CNGB3
|
Health Risk |
Pathogenic |
Achromatopsia, Achromatopsia 3 |
| RS765574676 |
ADGRV1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive sensorineural hearing loss, Hearing loss |
| RS765574993 |
HSD11B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765575482 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |