| RS765575912 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal Kniest-like syndrome, Schwartz-Jampel syndrome |
| RS765576835 |
FANCD2
|
Health Risk |
Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group D2 |
| RS765576893 |
TYK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 35, Immunodeficiency 35 |
| RS765577023 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS765577483 |
MCOLN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucolipidosis type IV, Lisch epithelial corneal dystrophy |
| RS765577880 |
AAAS
|
Health Risk |
Pathogenic |
Glucocorticoid deficiency with achalasia, Glucocorticoid deficiency with achalasia |
| RS765578315 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS765578621 |
CHD3
|
Health Risk |
Likely pathogenic |
Snijders Blok-Campeau syndrome, Snijders Blok-Campeau syndrome |
| RS765578870 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Rubinstein-Taybi syndrome |
| RS765578993 |
SLC25A38
|
Health Risk |
Conflicting classifications of pathogenicity |
Sideroblastic anemia 2, Sideroblastic anemia 2 |
| RS765579667 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS765580991 |
ABCC2
|
Health Risk |
Pathogenic |
— |
| RS765581751 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS765581827 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS765583923 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypobetalipoproteinemia, Hypercholesterolemia |
| RS765584669 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Dystrophin deficiency |
| RS765584733 |
PDGFRB
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile myofibromatosis, Skeletal overgrowth-craniofacial dysmorphism-hyperelastic skin-white matter lesions syndrome |
| RS765586205 |
MTHFR
|
Health Risk |
Pathogenic |
Homocystinuria due to methylene tetrahydrofolate reductase deficiency, Neural tube defects |
| RS765587517 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Patterned macular dystrophy 2 |
| RS765587923 |
NAXE
|
Health Risk |
Pathogenic |
Encephalopathy, progressive |
| RS765589827 |
SI
|
Health Risk |
Conflicting classifications of pathogenicity |
Sucrase-isomaltase deficiency, Sucrase-isomaltase deficiency |
| RS765590257 |
KCNJ10
|
Health Risk |
Conflicting classifications of pathogenicity |
EAST syndrome, Autosomal recessive nonsyndromic hearing loss 4 |
| RS765591205 |
MME
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease axonal type 2T, Charcot-Marie-Tooth disease axonal type 2T |
| RS765591278 |
FKRP
|
Health Risk |
Likely pathogenic |
Walker-Warburg congenital muscular dystrophy, Walker-Warburg congenital muscular dystrophy |
| RS765592025 |
LAMA2
|
Health Risk |
Likely pathogenic |
Merosin deficient congenital muscular dystrophy, Merosin deficient congenital muscular dystrophy |
| RS76559205 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765592794 |
ANO10
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive spinocerebellar ataxia 10, Uterine corpus endometrial carcinoma |
| RS765593474 |
POU3F4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, POU3F4-related disorder |
| RS765594825 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Cardiomyopathy |
| RS765595608 |
ALDH5A1
|
Health Risk |
Pathogenic |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS765596348 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Inborn genetic diseases |
| RS765596650 |
HNF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young, Maturity-onset diabetes of the young |
| RS765597017 |
MIB1
|
Health Risk |
Likely pathogenic |
— |
| RS765597431 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 7 |
| RS765598128 |
TMEM240
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765598266 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Cardiovascular phenotype |
| RS765598479 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS765600316 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, Inborn genetic diseases |
| RS765602610 |
PROM1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765602627 |
LIFR
|
Health Risk |
Pathogenic/Likely pathogenic |
Stüve-Wiedemann syndrome 1, Stüve-Wiedemann syndrome 1 |
| RS765602803 |
HSD3B2
|
Health Risk |
Pathogenic |
— |
| RS765603040 |
ALAS2
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked sideroblastic anemia 1, X-linked sideroblastic anemia 1 |
| RS765604322 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS765604641 |
BRWD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, X-linked 93 |
| RS765605645 |
GJB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 2B, Autosomal dominant nonsyndromic hearing loss 2B |
| RS765607332 |
PSAP
|
Health Risk |
Pathogenic |
Sphingolipid activator protein 1 deficiency, Sphingolipid activator protein 1 deficiency |
| RS765608680 |
GALNS
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-IV-A |
| RS765609390 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 13, Autosomal dominant nonsyndromic hearing loss 13 |
| RS765609579 |
SLC12A3
|
Health Risk |
Pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS765609971 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS765610106 |
ANKRD26
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765610436 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765610535 |
ASPH
|
Health Risk |
Pathogenic/Likely pathogenic |
Facial dysmorphism-lens dislocation-anterior segment abnormalities-spontaneous filtering blebs syndrome, Facial dysmorphism-lens dislocation-anterior segment abnormalities-spontaneous filtering blebs syndrome |
| RS765610848 |
SQSTM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Frontotemporal dementia and/or amyotrophic lateral sclerosis 1, Paget disease of bone 2 |
| RS765611426 |
CAD
|
Health Risk |
Pathogenic |
— |
| RS765612030 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765612286 |
PYGM
|
Health Risk |
Conflicting classifications of pathogenicity |
PYGM-related disorder, Glycogen storage disease |
| RS765613378 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS765613848 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS765613900 |
ASPM
|
Health Risk |
Pathogenic |
— |
| RS765613977 |
AAAS
|
Health Risk |
Pathogenic/Likely pathogenic |
Glucocorticoid deficiency with achalasia, Glucocorticoid deficiency with achalasia |
| RS765613994 |
DCDC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 66, Isolated neonatal sclerosing cholangitis |
| RS765614514 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS765615419 |
FGFR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 2 with or without anosmia, Pfeiffer syndrome |
| RS765616473 |
CUBN
|
Health Risk |
Likely pathogenic |
Imerslund-Grasbeck syndrome, CUBN-related disorder |
| RS765617846 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS765618026 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS765619483 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS765619817 |
LAMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765621362 |
LARS2
|
Health Risk |
Likely pathogenic |
— |
| RS765622092 |
FRAS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Fraser syndrome 1, Fraser syndrome 1 |
| RS765622323 |
LIFR
|
Health Risk |
Pathogenic/Likely pathogenic |
Stuve-Wiedemann syndrome, Stüve-Wiedemann syndrome 1 |
| RS765622787 |
TSC2
|
Health Risk |
Pathogenic |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS765625076 |
MAGEL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765626502 |
CEP152
|
Health Risk |
Pathogenic |
— |
| RS765627299 |
BAG3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1HH |
| RS765627692 |
MCPH1
|
Health Risk |
Pathogenic |
See cases, See cases |
| RS765628474 |
COL10A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Metaphyseal chondrodysplasia, Schmid type |
| RS765628527 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS765628635 |
TDRD7
|
Health Risk |
Pathogenic |
Cataract 36, Cataract 36 |
| RS765629130 |
BARD1
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS765629644 |
FH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary leiomyomatosis and renal cell cancer, Fumarase deficiency |
| RS765630867 |
CEP104
|
Health Risk |
Pathogenic |
Joubert syndrome 25, Joubert syndrome 25 |
| RS765630970 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765631918 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS765632065 |
ATP13A2
|
Health Risk |
Pathogenic/Likely pathogenic |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS765632713 |
DPF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Coffin-Siris syndrome 7, Coffin-Siris syndrome 7 |
| RS765632800 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765633380 |
GBA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gaucher disease type I, Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome |
| RS765633648 |
FRMPD4
|
Health Risk |
Conflicting classifications of pathogenicity |
FRMPD4-related disorder, FRMPD4-related disorder |
| RS765634975 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hereditary spastic paraplegia 30 |
| RS765635417 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS765636779 |
PRF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 2, Inborn genetic diseases |
| RS765636819 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765639766 |
EEFSEC
|
Health Risk |
Likely pathogenic |
Infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly, Neurodevelopmental disorder with progressive spasticity and brain abnormalities |
| RS765640131 |
ASPM
|
Health Risk |
Pathogenic |
— |
| RS765641195 |
LRSAM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2P, Charcot-Marie-Tooth disease axonal type 2P |
| RS765641686 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS765641913 |
NLRC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 4, Periodic fever-infantile enterocolitis-autoinflammatory syndrome |
| RS765641981 |
XPC
|
Health Risk |
Pathogenic/Likely pathogenic |
Xeroderma pigmentosum, group C |