NAXE Chromosome 1

NAD(P)HX epimerase
20 variants 20 Health Risk

Upload your DNA to see your personal genotypes for variants in NAXE.

What This Gene Does
The product of this gene interacts with apolipoprotein A-I (apoA-I), the major apolipoprotein of high-density lipoproteins (HDLs). It is secreted into some bodily fluids, and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I. The human genome contains related pseudogenes. [provided by RefSeq, Jul 2008]
Associated Conditions (6)
Encephalopathy
progressive
early-onset
with brain edema and/or leukoencephalopathy
1
NAXE-related disorder
Key Variants
All Variants (20)
RSID Category Clinical Significance Conditions
RS779820587 Health Risk Conflicting classifications of pathogenicity Encephalopathy, progressive, early-onset
RS886041062 Health Risk Conflicting classifications of pathogenicity Encephalopathy, progressive, early-onset
RS1205686109 Health Risk Likely pathogenic Encephalopathy, progressive, early-onset
RS1258884250 Health Risk Likely pathogenic NAXE-related disorder, NAXE-related disorder
RS2102491191 Health Risk Likely pathogenic Encephalopathy, progressive, early-onset
RS1064796609 Health Risk Pathogenic
RS1178037334 Health Risk Pathogenic
RS139093330 Health Risk Pathogenic Encephalopathy, progressive, early-onset
RS1677397982 Health Risk Pathogenic Encephalopathy, progressive, early-onset
RS1677398842 Health Risk Pathogenic Encephalopathy, progressive, early-onset
RS2102489197 Health Risk Pathogenic Encephalopathy, progressive, early-onset
RS2102489248 Health Risk Pathogenic Encephalopathy, progressive, early-onset
RS371872027 Health Risk Pathogenic Encephalopathy, progressive, early-onset
RS572486885 Health Risk Pathogenic
RS759251812 Health Risk Pathogenic Encephalopathy, progressive, early-onset
RS765587923 Health Risk Pathogenic Encephalopathy, progressive, early-onset
RS766617434 Health Risk Pathogenic
RS879255647 Health Risk Pathogenic Encephalopathy, progressive, early-onset
RS886041063 Health Risk Pathogenic Encephalopathy, progressive, early-onset
RS886041064 Health Risk Pathogenic Encephalopathy, progressive, early-onset
Sign Up to Analyze Your DNA Log In