| RS765389013 |
DNMT3A
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS765389300 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS765390290 |
ACADVL
|
Health Risk |
Conflicting classifications of pathogenicity |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS765390600 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS765390756 |
PKHD1
|
Health Risk |
Pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS765391058 |
COPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoimmune interstitial lung disease-arthritis syndrome, Inborn genetic diseases |
| RS765392662 |
BLM
|
Health Risk |
Likely pathogenic |
Bloom syndrome, Bloom syndrome |
| RS765393777 |
CLCN1
|
Health Risk |
Pathogenic |
Congenital myotonia, autosomal dominant form |
| RS765394037 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS765394821 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS765396527 |
NEXN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Dilated cardiomyopathy 1CC |
| RS765397845 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS765398055 |
AARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease axonal type 2N |
| RS76539814 |
GBA1
|
Health Risk |
Pathogenic/Likely pathogenic |
Gaucher disease type I, Gaucher disease type II |
| RS765398896 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS765401006 |
AAGAB
|
Health Risk |
Pathogenic |
— |
| RS765401548 |
TTLL5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765401924 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS765402802 |
LRP5
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Retinal dystrophy |
| RS765403158 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765403325 |
MAN1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Rafiq syndrome, Rafiq syndrome |
| RS765403861 |
NEB
|
Health Risk |
Pathogenic |
Nemaline myopathy 2, Nemaline myopathy |
| RS765404768 |
PEX12
|
Health Risk |
Pathogenic/Likely pathogenic |
Peroxisome biogenesis disorder type 3B, Peroxisome biogenesis disorder 3A (Zellweger) |
| RS765405352 |
ABCC6
|
Health Risk |
Pathogenic |
Autosomal recessive inherited pseudoxanthoma elasticum, Autosomal recessive inherited pseudoxanthoma elasticum |
| RS765405386 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Alstrom syndrome |
| RS765405975 |
RASA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Capillary malformation-arteriovenous malformation syndrome, Cardiovascular phenotype |
| RS765406506 |
CTC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, Inborn genetic diseases |
| RS765406631 |
PTS
|
Health Risk |
Pathogenic |
6-Pyruvoyl-tetrahydrobiopterin synthase deficiency, 6-Pyruvoyl-tetrahydrobiopterin synthase deficiency |
| RS765407874 |
TBCK
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypotonia, infantile |
| RS765408537 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hematuria, Hematuria |
| RS765409185 |
KCNJ10
|
Health Risk |
Likely pathogenic |
EAST syndrome, EAST syndrome |
| RS765409417 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia |
| RS765410591 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, Acute febrile neutrophilic dermatosis |
| RS765410747 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765411357 |
AIPL1
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis 4, AIPL1-related retinopathy |
| RS765411726 |
DNAJC21
|
Health Risk |
Pathogenic |
Bone marrow failure syndrome 3, Bone marrow failure syndrome 3 |
| RS765411990 |
MSH6
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS765412618 |
RSPH4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765415312 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Rubinstein-Taybi syndrome |
| RS765416276 |
MLYCD
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of malonyl-CoA decarboxylase, Deficiency of malonyl-CoA decarboxylase |
| RS765416558 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, PTEN hamartoma tumor syndrome |
| RS765416883 |
VPS33B
|
Health Risk |
Likely pathogenic |
Cholestasis, progressive familial intrahepatic |
| RS765417421 |
SLC25A12
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765417606 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked intellectual disability with marfanoid habitus, FG syndrome 1 |
| RS765417610 |
DNAH1
|
Health Risk |
Pathogenic/Likely pathogenic |
Spermatogenic failure 18, Ciliary dyskinesia |
| RS765418194 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS765419233 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Peutz-Jeghers syndrome |
| RS765419741 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Germ cell tumor of testis |
| RS765420779 |
DYSF
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Distal myopathy with anterior tibial onset |
| RS765420811 |
NBAS
|
Health Risk |
Pathogenic/Likely pathogenic |
Infantile liver failure syndrome 2, Short stature-optic atrophy-Pelger-Huët anomaly syndrome |
| RS765421411 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS765421461 |
FANCM
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Hereditary breast ovarian cancer syndrome |
| RS765421589 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS76542238 |
PAH
|
Health Risk |
Pathogenic |
Phenylketonuria, PAH-related disorder |
| RS765422613 |
GP1BA
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765423180 |
TGM6
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 35, Spinocerebellar ataxia type 35 |
| RS765423555 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome, Brain small vessel disease 1 with or without ocular anomalies |
| RS765423779 |
ACADVL
|
Health Risk |
Conflicting classifications of pathogenicity |
Very long chain acyl-CoA dehydrogenase deficiency, ACADVL-related disorder |
| RS765424230 |
ANKRD26
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS76542495 |
SGCA
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Autosomal recessive limb-girdle muscular dystrophy type 2D |
| RS765424967 |
MAGEL2
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS765425127 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis-Noonan syndrome |
| RS765425704 |
PYGL
|
Health Risk |
Pathogenic |
Glycogen storage disease, type VI |
| RS765426068 |
CYP27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cholestanol storage disease, Cholestanol storage disease |
| RS765426544 |
BAG3
|
Health Risk |
Pathogenic |
Myofibrillar myopathy 6, Dilated cardiomyopathy 1HH |
| RS765427343 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS765427546 |
MOGS
|
Health Risk |
Pathogenic/Likely pathogenic |
MOGS-congenital disorder of glycosylation, MOGS-related disorder |
| RS765427574 |
ANO5
|
Health Risk |
Pathogenic |
— |
| RS765428922 |
NDUFAF5
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex I deficiency, nuclear type 16 |
| RS765429911 |
ABCA4
|
Health Risk |
Pathogenic |
Retinal dystrophy, Severe early-childhood-onset retinal dystrophy |
| RS765430577 |
ECEL1
|
Health Risk |
Pathogenic/Likely pathogenic |
Distal arthrogryposis type 5D, Distal arthrogryposis type 5D |
| RS765431150 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated Nonsyndromic Congenital Heart Disease, Alagille syndrome due to a JAG1 point mutation |
| RS765432081 |
HNF1A
|
Health Risk |
Likely pathogenic |
Diabetes mellitus, Monogenic diabetes |
| RS765432568 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS765433263 |
PMM2
|
Health Risk |
Pathogenic/Likely pathogenic |
PMM2-congenital disorder of glycosylation, PMM2-related disorder |
| RS765433422 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
PTEN hamartoma tumor syndrome, Cowden syndrome 1 |
| RS765434534 |
GSS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inherited glutathione synthetase deficiency, Inherited glutathione synthetase deficiency |
| RS765435429 |
CRPPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A |
| RS765435961 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 5, Dilated Cardiomyopathy |
| RS765436350 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS765436929 |
MAP1A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765436962 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS765437414 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS765437818 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS765438239 |
MCCC2
|
Health Risk |
Pathogenic/Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 2 deficiency, Methylcrotonyl-CoA carboxylase deficiency |
| RS765438249 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS765438313 |
RHO
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone dystrophy 3, Retinal dystrophy |
| RS765438725 |
DUOX2
|
Health Risk |
Pathogenic/Likely pathogenic |
Thyroid dyshormonogenesis 6, Thyroid dyshormonogenesis 6 |
| RS765438770 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, FLNC-related disorder |
| RS765442101 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS765442907 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, Inborn genetic diseases |
| RS765443036 |
CYP7B1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 5A, Hereditary spastic paraplegia 5A |
| RS765443042 |
RAB23
|
Health Risk |
Pathogenic/Likely pathogenic |
RAB23-related Carpenter syndrome, Carpenter syndrome |
| RS765443815 |
CACNA1E
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 69 |
| RS765444423 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS765444467 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS765444519 |
TCIRG1
|
Health Risk |
Likely pathogenic |
Autosomal recessive osteopetrosis 1, Autosomal recessive osteopetrosis 1 |
| RS765445413 |
SERPINC1
|
Health Risk |
Likely pathogenic |
Hereditary antithrombin deficiency, SERPINC1-related disorder |
| RS765445866 |
DMD
|
Health Risk |
Pathogenic |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS765448103 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |