| RS765217736 |
USH2A
|
Health Risk |
Likely pathogenic |
— |
| RS765219004 |
HGD
|
Health Risk |
Likely pathogenic |
Alkaptonuria, Alkaptonuria |
| RS765219776 |
ADA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Sneddon syndrome |
| RS765221332 |
PNPLA6
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 39, Hereditary spastic paraplegia 39 |
| RS765223725 |
NPAT
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765224300 |
RPGR
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765224364 |
DYNC2H1
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS765224443 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS765227211 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Kleefstra syndrome 1 |
| RS765227276 |
TUT1
|
Health Risk |
Likely pathogenic |
Abnormal brain morphology, Abnormal brain morphology |
| RS765227366 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS765227931 |
KIAA0586
|
Health Risk |
Likely pathogenic |
Short-rib thoracic dysplasia 14 with polydactyly, Joubert syndrome 23 |
| RS765230559 |
GLB1
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-IV-B |
| RS765230689 |
POMT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2K, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS765231294 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS765231668 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS765231758 |
MME
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease axonal type 2T, Charcot-Marie-Tooth disease axonal type 2T |
| RS765232270 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS765232439 |
CSF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765232909 |
PRF1
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, Familial hemophagocytic lymphohistiocytosis 2 |
| RS765233016 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS765233032 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS765233946 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS765235179 |
TTI2
|
Health Risk |
Pathogenic |
Severe intellectual disability-short stature-behavioral abnormalities-facial dysmorphism syndrome, Severe intellectual disability-short stature-behavioral abnormalities-facial dysmorphism syndrome |
| RS765235194 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial meningioma, Hereditary cancer-predisposing syndrome |
| RS765235486 |
KCTD7
|
Health Risk |
Likely pathogenic |
Progressive myoclonic epilepsy type 3, Progressive myoclonic epilepsy type 3 |
| RS765235707 |
COQ8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia due to ubiquinone deficiency, Autosomal recessive ataxia due to ubiquinone deficiency |
| RS765235945 |
OCA2
|
Health Risk |
Pathogenic |
OCA2-related disorder, OCA2-related disorder |
| RS765237563 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS765237801 |
PCLO
|
Health Risk |
Pathogenic |
— |
| RS765238394 |
RYR2
|
Health Risk |
Likely pathogenic |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS765239220 |
SPTBN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Developmental delay |
| RS765239404 |
ZMIZ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765240540 |
SLC12A3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765240700 |
ARL13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 8, Joubert syndrome 8 |
| RS765241115 |
RYR1
|
Health Risk |
Pathogenic |
RYR1-related disorder, RYR1-related disorder |
| RS765242131 |
MKS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS765243124 |
COL17A1
|
Health Risk |
Pathogenic |
COL17A1-related disorder, Epithelial recurrent erosion dystrophy |
| RS765244598 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS765245807 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS765246704 |
SLC10A1
|
Health Risk |
Conflicting classifications of pathogenicity |
SLC10A1-related disorder, Hypercholanemia |
| RS765246909 |
B3GAT3
|
Health Risk |
Conflicting classifications of pathogenicity |
Larsen-like syndrome, B3GAT3 type |
| RS765247025 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS765247380 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS765248215 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS765249238 |
SLCO2A1
|
Health Risk |
Pathogenic |
Hypertrophic osteoarthropathy, primary |
| RS765250980 |
CPLANE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Orofaciodigital syndrome type 6 |
| RS765251030 |
CHKB
|
Health Risk |
Conflicting classifications of pathogenicity |
Megaconial type congenital muscular dystrophy, Inborn genetic diseases |
| RS765251347 |
PKHD1
|
Health Risk |
Pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS765251445 |
PNPLA8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765251991 |
SHOX
|
Health Risk |
Pathogenic |
Leri-Weill dyschondrosteosis, Leri-Weill dyschondrosteosis |
| RS765253165 |
TCF4
|
Health Risk |
Likely pathogenic |
Pitt-Hopkins syndrome, Pitt-Hopkins syndrome |
| RS765254190 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS765255206 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS765255437 |
SAG
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS765256075 |
CCDC88C
|
Health Risk |
Pathogenic |
— |
| RS765256758 |
CLDN16
|
Health Risk |
Likely pathogenic |
Primary hypomagnesemia, Primary hypomagnesemia |
| RS765257420 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS765257439 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS765257706 |
DBT
|
Health Risk |
Likely pathogenic |
Maple syrup urine disease, Maple syrup urine disease |
| RS765257726 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS765257753 |
PNPLA6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 39, Hereditary spastic paraplegia 39 |
| RS765257824 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dehydrated hereditary stomatocytosis with or without pseudohyperkalemia and/or perinatal edema, Dehydrated hereditary stomatocytosis with or without pseudohyperkalemia and/or perinatal edema |
| RS765257989 |
MYO1F
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765258483 |
KAT6A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765258547 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS765259371 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS765259892 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765259917 |
TAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class I deficiency, Inborn genetic diseases |
| RS765261158 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS765262083 |
ANO5
|
Health Risk |
Pathogenic |
— |
| RS765263589 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiomyopathy |
| RS765263617 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Tuberous sclerosis syndrome |
| RS765263670 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS765263671 |
NPHP1
|
Health Risk |
Pathogenic |
Nephronophthisis, Joubert syndrome with renal defect |
| RS765264117 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765264494 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Pulmonary fibrosis and/or bone marrow failure, Telomere-related |
| RS765265404 |
ACTB
|
Health Risk |
Pathogenic |
Baraitser-Winter syndrome 1, Baraitser-Winter syndrome 1 |
| RS765266179 |
EP300
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome due to EP300 haploinsufficiency, EP300-related disorder |
| RS765266988 |
GFM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1, Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1 |
| RS765267560 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765268971 |
GLDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycine encephalopathy, Glycine encephalopathy |
| RS765269619 |
EVC
|
Health Risk |
Pathogenic/Likely pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS765269946 |
GLE1
|
Health Risk |
Likely pathogenic |
Lethal arthrogryposis-anterior horn cell disease syndrome, Lethal arthrogryposis-anterior horn cell disease syndrome |
| RS765271127 |
RAD51D
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS765271720 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Polyps |
| RS765273768 |
TCOF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Ehlers-Danlos syndrome |
| RS765273968 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS765274194 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS765274398 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS765274435 |
MYH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Distal arthrogryposis type 2B1, Freeman-Sheldon syndrome |
| RS765274871 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, ankyrin-B-related |
| RS765274952 |
LRP6
|
Health Risk |
Pathogenic |
— |
| RS765275156 |
EXT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple congenital exostosis, Multiple congenital exostosis |
| RS765275884 |
ASPM
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly 5, primary |
| RS765276365 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765276419 |
POMT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A2 |
| RS765276422 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS765276497 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS765277254 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |