| RS765344513 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, Hereditary spastic paraplegia |
| RS765345575 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Medulloblastoma |
| RS765346043 |
POMT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A2 |
| RS765346218 |
GDAP1
|
Health Risk |
Likely pathogenic |
Peripheral neuropathy, Peripheral neuropathy |
| RS765346539 |
USH1C
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 18A, Usher syndrome type 1C |
| RS765347389 |
DSG2
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Arrhythmogenic right ventricular dysplasia 10 |
| RS76534745 |
RET
|
Health Risk |
Likely pathogenic |
Hirschsprung disease, susceptibility to |
| RS765347562 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
BAP1-related tumor predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS765347751 |
SLC12A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Bartter disease type 1, Bartter disease type 1 |
| RS765348415 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765348942 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS765349480 |
ADCY5
|
Health Risk |
Likely pathogenic |
— |
| RS765351308 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Cardiovascular phenotype |
| RS765351669 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sotos syndrome, Sotos syndrome |
| RS765351696 |
SLX4
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group P |
| RS765352313 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS765353150 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS765353265 |
HESX1
|
Health Risk |
Conflicting classifications of pathogenicity |
GROWTH HORMONE DEFICIENCY WITH PITUITARY ANOMALIES, Septo-optic dysplasia sequence |
| RS765353795 |
GALE
|
Health Risk |
Pathogenic/Likely pathogenic |
UDPglucose-4-epimerase deficiency, Thrombocytopenia 13 |
| RS765353898 |
TDRD9
|
Health Risk |
Pathogenic |
Spermatogenic failure 30, Azoospermia |
| RS765354113 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial meningioma, Hereditary cancer-predisposing syndrome |
| RS765354372 |
ETV6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765355046 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Duchenne muscular dystrophy |
| RS765355244 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Primary dilated cardiomyopathy |
| RS765355281 |
DNAH5
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS765356009 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS765356177 |
WDPCP
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome, Heart defect - tongue hamartoma - polysyndactyly syndrome |
| RS765357382 |
MYT1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765358771 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Medulloblastoma, Gorlin syndrome |
| RS765358773 |
SLC25A13
|
Health Risk |
Conflicting classifications of pathogenicity |
Citrin deficiency, Citrullinemia |
| RS765359025 |
TNNT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 2, Cardiomyopathy |
| RS765359111 |
VCAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Vitreoretinopathy, Inborn genetic diseases |
| RS765360600 |
NRXN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pitt-Hopkins-like syndrome 2, Pitt-Hopkins-like syndrome 2 |
| RS765360653 |
GAA
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type II |
| RS765361338 |
CDK4
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial melanoma, Hereditary cancer-predisposing syndrome |
| RS765361603 |
SGSH
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-A |
| RS765361834 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS765361868 |
SACS
|
Health Risk |
Pathogenic |
Charlevoix-Saguenay spastic ataxia, Hereditary spastic paraplegia |
| RS765361885 |
XPA
|
Health Risk |
Pathogenic |
— |
| RS765362140 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS765362255 |
SMCHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Facioscapulohumeral muscular dystrophy 2, Facioscapulohumeral muscular dystrophy 2 |
| RS765362308 |
GAA
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type II |
| RS765362355 |
HPS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 1, Hermansky-Pudlak syndrome |
| RS765363585 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS765365713 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS765366351 |
SETBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765366810 |
EPAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765367405 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS765367813 |
TSHR
|
Health Risk |
Likely pathogenic |
Hypothyroidism due to TSH receptor mutations, Hypothyroidism due to TSH receptor mutations |
| RS765367820 |
RCBTB1
|
Health Risk |
Pathogenic |
RCBTB1-related retinopathy, RCBTB1-related retinopathy |
| RS765367881 |
GNAT2
|
Health Risk |
Pathogenic |
— |
| RS765368797 |
HSPA9
|
Health Risk |
Pathogenic |
Even-plus syndrome, Even-plus syndrome |
| RS765368974 |
ELAC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation defect type 17, Inborn genetic diseases |
| RS765369750 |
RAB27A
|
Health Risk |
Pathogenic |
Griscelli syndrome type 2, Griscelli syndrome type 2 |
| RS765369803 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome and Noonan-related syndrome, RASopathy |
| RS765370709 |
RAD50
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS765370870 |
MAX
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pheochromocytoma and paraganglioma, Hereditary cancer-predisposing syndrome |
| RS765371196 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Irido-corneo-trabecular dysgenesis, Gorlin syndrome |
| RS765371462 |
LAMP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Danon disease, Danon disease |
| RS765371601 |
SETX
|
Health Risk |
Pathogenic/Likely pathogenic |
SETX-related disorder, Spinocerebellar ataxia |
| RS765371898 |
MORC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2Z, Charcot-Marie-Tooth disease axonal type 2Z |
| RS765373403 |
MMUT
|
Health Risk |
Pathogenic/Likely pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic aciduria due to complete methylmalonyl-CoA mutase deficiency |
| RS765373503 |
FMO3
|
Health Risk |
Pathogenic |
Trimethylaminuria, Trimethylaminuria |
| RS765373729 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS765374050 |
PRKAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal congenital glycogen storage disease of heart, Cardiovascular phenotype |
| RS765374888 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 11 |
| RS765375271 |
DCHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765375312 |
TCTN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Orofacial-digital syndrome IV, Joubert syndrome 18 |
| RS76537615 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hypothermia, RYR1-related disorder |
| RS765376630 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, Cystic fibrosis |
| RS765376986 |
ADGRV1
|
Health Risk |
Pathogenic |
Usher syndrome type 2C, Retinal dystrophy |
| RS765377074 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS765377141 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS765377738 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS765378190 |
GTF2H5
|
Health Risk |
Likely pathogenic |
Trichothiodystrophy 3, photosensitive |
| RS765378243 |
ABCD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylmalonic acidemia with homocystinuria, type cblJ |
| RS76537883 |
CNGA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS765379481 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS765379963 |
TMCO1
|
Health Risk |
Pathogenic/Likely pathogenic |
Craniofacial dysmorphism, skeletal anomalies |
| RS765380141 |
PDE4D
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765380155 |
TPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 2, Neuronal ceroid lipofuscinosis 2 |
| RS765380273 |
ALDH18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spondyloepiphyseal dysplasia, Stanescu type |
| RS765380383 |
DUOX2
|
Health Risk |
Pathogenic/Likely pathogenic |
Thyroid dyshormonogenesis 6, Thyroid dyshormonogenesis 6 |
| RS765380976 |
SLC25A15
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome, Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome |
| RS765382079 |
PITX2
|
Health Risk |
Pathogenic |
Anterior segment dysgenesis 4, Axenfeld-Rieger syndrome type 1 |
| RS765382139 |
ABCC9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrichotic osteochondrodysplasia Cantu type, Dilated cardiomyopathy 1O |
| RS765382317 |
POLR3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism, Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism |
| RS765382334 |
SCNN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765383904 |
ATF6
|
Health Risk |
Likely pathogenic |
Achromatopsia, Achromatopsia |
| RS765384489 |
GLDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycine encephalopathy, Glycine encephalopathy 1 |
| RS765384591 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Familial adenomatous polyposis 1 |
| RS765384642 |
PCDH15
|
Health Risk |
Pathogenic |
— |
| RS765385264 |
BEST1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Autosomal recessive bestrophinopathy |
| RS765386143 |
TRAF7
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac, facial |
| RS765386646 |
DNAH8
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765387131 |
FBN1
|
Health Risk |
Likely pathogenic |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS765387680 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS765387808 |
NFASC
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder with central and peripheral motor dysfunction, Neurodevelopmental disorder with central and peripheral motor dysfunction |
| RS765388136 |
MYZAP
|
Health Risk |
Likely pathogenic |
Cardiomyopathy, dilated |
| RS765388755 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |