| RS764554878 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS764556085 |
ARID1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764556767 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Collagen 6-related myopathy |
| RS764557236 |
HADHA
|
Health Risk |
Pathogenic/Likely pathogenic |
Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency, Mitochondrial trifunctional protein deficiency |
| RS764559304 |
EOGT
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 4, Inborn genetic diseases |
| RS764559444 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS764559670 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Alternating hemiplegia of childhood 1, Migraine |
| RS764560018 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS764560431 |
SPTB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764561297 |
HNF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperechogenic kidneys, Maturity-onset diabetes of the young |
| RS764561670 |
TRIP11
|
Health Risk |
Pathogenic |
Achondrogenesis, type IA |
| RS764561909 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS764564256 |
ABCC8
|
Health Risk |
Likely pathogenic |
Hyperinsulinemic hypoglycemia, familial |
| RS764564753 |
KCNE5
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Brugada syndrome |
| RS764565613 |
TMEM126B
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial complex I deficiency, nuclear type 29 |
| RS764566232 |
IBA57
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hereditary spastic paraplegia 74 |
| RS764566414 |
ABCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCC2-related disorder, ABCC2-related disorder |
| RS764567774 |
PGAM2
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease type X, Glycogen storage disease type X |
| RS764568010 |
IMPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS764568129 |
DNAJC19
|
Health Risk |
Pathogenic |
3-methylglutaconic aciduria type 5, 3-methylglutaconic aciduria type 5 |
| RS764568339 |
EPG5
|
Health Risk |
Conflicting classifications of pathogenicity |
Vici syndrome, Inborn genetic diseases |
| RS764568533 |
ACAT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of acetyl-CoA acetyltransferase, Deficiency of acetyl-CoA acetyltransferase |
| RS764568599 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS764569458 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Inborn genetic diseases |
| RS764569623 |
GCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
GTP cyclohydrolase I deficiency, Dystonia 5 |
| RS764570434 |
TECTA
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764570495 |
ELAC2
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation defect type 17, Combined oxidative phosphorylation defect type 17 |
| RS764570645 |
MEN1
|
Health Risk |
Pathogenic |
Multiple endocrine neoplasia, type 1 |
| RS764571295 |
CLN6
|
Health Risk |
Conflicting classifications of pathogenicity |
Ceroid lipofuscinosis, neuronal |
| RS764571605 |
SPTB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764571894 |
KCNC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 13, Inborn genetic diseases |
| RS764572758 |
XPC
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group C |
| RS764574133 |
ABCC9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrichotic osteochondrodysplasia Cantu type, Dilated cardiomyopathy 1O |
| RS764574987 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy 5, Developmental and epileptic encephalopathy |
| RS764575492 |
DLG5
|
Health Risk |
Pathogenic |
Yuksel-Vogel-Bauer syndrome, Yuksel-Vogel-Bauer syndrome |
| RS764575966 |
SDHC
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Pheochromocytoma/paraganglioma syndrome 3 |
| RS764576683 |
CTNNB1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764577626 |
NANS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spondyloepimetaphyseal dysplasia, Genevieve type |
| RS764577786 |
KIF14
|
Health Risk |
Conflicting classifications of pathogenicity |
KIF14-related disorder, KIF14-related disorder |
| RS764578014 |
MYH3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764578297 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS764579746 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS764579762 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS764580322 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS764581483 |
ABCB11
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive familial intrahepatic cholestasis type 2, Benign recurrent intrahepatic cholestasis type 2 |
| RS764581574 |
LAMA1
|
Health Risk |
Pathogenic |
Ataxia - intellectual disability - oculomotor apraxia - cerebellar cysts syndrome, Ataxia - intellectual disability - oculomotor apraxia - cerebellar cysts syndrome |
| RS764582394 |
XPA
|
Health Risk |
Pathogenic/Likely pathogenic |
Xeroderma pigmentosum group A, Xeroderma pigmentosum group A |
| RS764583466 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS764583480 |
BRAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal-onset encephalopathy with rigidity and seizures, Neonatal-onset encephalopathy with rigidity and seizures |
| RS764583678 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1AA, Primary familial hypertrophic cardiomyopathy |
| RS764583867 |
ADGRV1
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2C, Febrile seizures |
| RS764584080 |
DPYD
|
Health Risk |
Likely pathogenic |
Dihydropyrimidine dehydrogenase deficiency, Dihydropyrimidine dehydrogenase deficiency |
| RS764585158 |
SACS
|
Health Risk |
Likely pathogenic |
— |
| RS764585550 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group J |
| RS76458556 |
CYB5R3
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental delay, CYB5R3-related disorder |
| RS764586079 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy 1, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS764587648 |
COQ8B
|
Health Risk |
Pathogenic |
Nephrotic syndrome, type 9 |
| RS764588235 |
WWOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive spinocerebellar ataxia 12, Developmental and epileptic encephalopathy |
| RS764588340 |
AIRE
|
Health Risk |
Likely pathogenic |
Polyglandular autoimmune syndrome, type 1 |
| RS764588746 |
ALDH7A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Pyridoxine-dependent epilepsy, Melanoma |
| RS764589321 |
WRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Werner syndrome, Werner syndrome |
| RS764589468 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS764591009 |
AGL
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS764591027 |
DHTKD1
|
Health Risk |
Pathogenic |
2-aminoadipic 2-oxoadipic aciduria, 2-aminoadipic 2-oxoadipic aciduria |
| RS764591347 |
SLC26A3
|
Health Risk |
Likely pathogenic |
— |
| RS764591495 |
VPS13A
|
Health Risk |
Likely pathogenic |
Chorea-acanthocytosis, Chorea-acanthocytosis |
| RS764592601 |
ATP7B
|
Health Risk |
Likely pathogenic |
Wilson disease, Wilson disease |
| RS764592751 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS764593071 |
SDR9C7
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital ichthyosis of skin, Ichthyosis |
| RS764594515 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Cardiovascular phenotype |
| RS764594811 |
CNGA1
|
Health Risk |
Pathogenic |
— |
| RS764595221 |
SPEN
|
Health Risk |
Pathogenic |
Neurodevelopmental abnormality, Radio-Tartaglia syndrome |
| RS764595344 |
PAX9
|
Health Risk |
Pathogenic |
Oligodontia, Oligodontia |
| RS764595667 |
PPP2CA
|
Health Risk |
Likely pathogenic |
Houge-Janssens syndrome 3, Houge-Janssens syndrome 3 |
| RS764596094 |
PRF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis, Familial hemophagocytic lymphohistiocytosis 2 |
| RS764596712 |
TRIP11
|
Health Risk |
Conflicting classifications of pathogenicity |
Achondrogenesis, type IA |
| RS764596973 |
OPTN
|
Health Risk |
Pathogenic/Likely pathogenic |
OPTN-related disorder, Primary open angle glaucoma |
| RS764597996 |
SP110
|
Health Risk |
Likely pathogenic |
Hepatic veno-occlusive disease-immunodeficiency syndrome, Hepatic veno-occlusive disease-immunodeficiency syndrome |
| RS764598023 |
CYP11B1
|
Health Risk |
Likely pathogenic |
Deficiency of steroid 11-beta-monooxygenase, Glucocorticoid-remediable aldosteronism |
| RS764598121 |
AGA
|
Health Risk |
Pathogenic |
Aspartylglucosaminuria, Aspartylglucosaminuria |
| RS764599897 |
CBL
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Juvenile myelomonocytic leukemia |
| RS76460090 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS764600940 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS764601493 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, familial spinal |
| RS764601859 |
KIF21A
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital fibrosis of extraocular muscles type 1, Inborn genetic diseases |
| RS764601903 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS764601965 |
MARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency, Charcot-Marie-Tooth disease axonal type 2U |
| RS764602074 |
PCNT
|
Health Risk |
Pathogenic |
Microcephalic osteodysplastic primordial dwarfism type II, Microcephalic osteodysplastic primordial dwarfism type II |
| RS764602105 |
CEP152
|
Health Risk |
Pathogenic/Likely pathogenic |
Seckel syndrome 5, Microcephaly 9 |
| RS764602422 |
ASL
|
Health Risk |
Pathogenic/Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS764602570 |
RYR1
|
Health Risk |
Likely pathogenic |
Congenital multicore myopathy with external ophthalmoplegia, Central core myopathy |
| RS764602705 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal dominant 2 |
| RS764603059 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS764603742 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS764603796 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS764604229 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS764605074 |
COL7A1
|
Health Risk |
Pathogenic |
— |
| RS764605140 |
PDE6B
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital stationary night blindness autosomal dominant 2, Retinitis pigmentosa 40 |
| RS764605841 |
EIF4A2
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder, Neurodevelopmental disorder |
| RS764605890 |
GAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Giant axonal neuropathy 1, Inborn genetic diseases |