| RS746135465 |
BUB1B
|
Health Risk |
Pathogenic |
Mosaic variegated aneuploidy syndrome 1, Mosaic variegated aneuploidy syndrome 1 |
| RS746135723 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS746136472 |
ACADM
|
Health Risk |
Conflicting classifications of pathogenicity |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS746136883 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS746138428 |
GFRA1
|
Health Risk |
Pathogenic |
Renal hypodysplasia/aplasia 4, Renal hypodysplasia/aplasia 4 |
| RS746138504 |
MOCS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sulfite oxidase deficiency due to molybdenum cofactor deficiency type A, Inborn genetic diseases |
| RS746139865 |
GARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2D, Neuronopathy |
| RS746139953 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS746141070 |
PDE6B
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 40, Retinal dystrophy |
| RS746141726 |
ZNF341
|
Health Risk |
Pathogenic |
Hyper-IgE recurrent infection syndrome 3, autosomal recessive |
| RS746142129 |
XRCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Spermatogenic failure 50 |
| RS746145270 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS746145535 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS746146532 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Inborn genetic diseases |
| RS746146690 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Transitory neonatal diabetes mellitus, Maturity-onset diabetes of the young |
| RS746147472 |
PCLO
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746147610 |
DVL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746147656 |
NTRK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746148722 |
SMCHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Facioscapulohumeral muscular dystrophy 2, Facioscapulohumeral muscular dystrophy 2 |
| RS746149047 |
NF1
|
Health Risk |
Pathogenic |
Neurofibromatosis, type 1 |
| RS746150420 |
NLRP7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hydatidiform mole, recurrent |
| RS746150931 |
ROBO2
|
Health Risk |
Conflicting classifications of pathogenicity |
ROBO2-related disorder, Vesicoureteral reflux 2 |
| RS746151218 |
SI
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Sucrase-isomaltase deficiency |
| RS746152064 |
PEX3
|
Health Risk |
Likely pathogenic |
— |
| RS746152219 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
PTEN hamartoma tumor syndrome, Cowden syndrome 1 |
| RS746152246 |
CDH23
|
Health Risk |
Pathogenic/Likely pathogenic |
Childhood onset hearing loss, Pituitary adenoma 5 |
| RS746152408 |
ADAR
|
Health Risk |
Conflicting classifications of pathogenicity |
Symmetrical dyschromatosis of extremities, Aicardi-Goutieres syndrome 6 |
| RS746153198 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Patterned macular dystrophy 2 |
| RS746154279 |
TRNT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome, TRNT1-related disorder |
| RS746155183 |
SLX4
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group P |
| RS746155190 |
SLC25A13
|
Health Risk |
Pathogenic |
Neonatal intrahepatic cholestasis due to citrin deficiency, Citrin deficiency |
| RS746155226 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS746155423 |
COQ9
|
Health Risk |
Pathogenic |
— |
| RS746155701 |
SERPINA1
|
Health Risk |
Likely pathogenic |
Alpha-1-antitrypsin deficiency, Alpha-1-antitrypsin deficiency |
| RS746156911 |
WDR62
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 2, primary |
| RS746158069 |
KIAA0586
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 14 with polydactyly, Joubert syndrome 23 |
| RS746158689 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 3B, Dilated cardiomyopathy 3B |
| RS746159001 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS746159424 |
ERCC6
|
Health Risk |
Likely pathogenic |
Cockayne syndrome type 2, Cockayne syndrome type 2 |
| RS746159592 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS746159648 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, COL6A2-related disorder |
| RS746159728 |
LRSAM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease axonal type 2P, Charcot-Marie-Tooth disease axonal type 2P |
| RS746160070 |
TMPO
|
Health Risk |
Conflicting classifications of pathogenicity |
Loeys-Dietz syndrome 2, Loeys-Dietz syndrome 2 |
| RS746160626 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS746160756 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS746161025 |
POMT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1 |
| RS746161154 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS746163041 |
SCN2A
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 11 |
| RS746163138 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS746163664 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
CHD8-related disorder, Inborn genetic diseases |
| RS746164022 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS746164064 |
CEACAM16
|
Health Risk |
Conflicting classifications of pathogenicity |
Nonsyndromic genetic hearing loss, Hearing loss |
| RS746165168 |
SDHA
|
Health Risk |
Pathogenic |
Mitochondrial complex II deficiency, nuclear type 1 |
| RS746165832 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Rhabdoid tumor predisposition syndrome 2 |
| RS746166271 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS746166328 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
Bone marrow hypocellularity, DDX41-related hematologic malignancy predisposition syndrome |
| RS746166372 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS746166913 |
ABCB4
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCB4-related disorder, ABCB4-related disorder |
| RS746169425 |
SUMF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple sulfatase deficiency, Multiple sulfatase deficiency |
| RS746169492 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS746170176 |
C1QBP
|
Health Risk |
Pathogenic |
— |
| RS746170558 |
PRPF8
|
Health Risk |
Pathogenic |
— |
| RS746171104 |
BBS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 2, Bardet-Biedl syndrome |
| RS746171271 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS746173019 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS746173483 |
PEX16
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 8A (Zellweger), Peroxisome biogenesis disorder |
| RS746173561 |
DSC2
|
Health Risk |
Likely pathogenic |
Arrhythmogenic right ventricular dysplasia 11, Arrhythmogenic right ventricular dysplasia 11 |
| RS746174066 |
TNFRSF6B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746174154 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS746174328 |
PROM1
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 41, Retinal dystrophy |
| RS746175107 |
GNPTAB
|
Health Risk |
Likely pathogenic |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS746175548 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS746176365 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia |
| RS746177025 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS746177210 |
DSP
|
Health Risk |
Likely pathogenic |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS746177326 |
SYNE1
|
Health Risk |
Pathogenic/Likely pathogenic |
Arthrogryposis multiplex congenita 3, myogenic type |
| RS746177544 |
GOSR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myoclonic epilepsy type 6, Muscular dystrophy |
| RS746177794 |
TPM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myopathy 23, Arthrogryposis |
| RS746177907 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS746177928 |
DYRK1A
|
Health Risk |
Pathogenic |
Complex neurodevelopmental disorder, DYRK1A-related intellectual disability syndrome |
| RS746178364 |
SLX4
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS746178942 |
SLC27A4
|
Health Risk |
Pathogenic |
Ichthyosis prematurity syndrome, Ichthyosis prematurity syndrome |
| RS746180213 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 10 |
| RS746180658 |
MPV17
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746180694 |
ADSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Adenylosuccinate lyase deficiency, Inborn genetic diseases |
| RS746181375 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS746182820 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, FLNC-related disorder |
| RS746183321 |
NIPBL
|
Health Risk |
Conflicting classifications of pathogenicity |
Cornelia de Lange syndrome 1, Cornelia de Lange syndrome 1 |
| RS746183882 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 5, Cardiovascular phenotype |
| RS746183974 |
TMEM43
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 5, Cardiomyopathy |
| RS746184019 |
CHST6
|
Health Risk |
Pathogenic |
Macular corneal dystrophy, Macular corneal dystrophy |
| RS746184552 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS746186338 |
TCTN2
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS746187344 |
SLC22A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal carnitine transport defect, SLC22A5-related disorder |
| RS746187785 |
DPAGT1
|
Health Risk |
Conflicting classifications of pathogenicity |
DPAGT1-congenital disorder of glycosylation, Congenital myasthenic syndrome 13 |
| RS746192125 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746193063 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS746193653 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS746194866 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS746195311 |
BLM
|
Health Risk |
Pathogenic |
Bloom syndrome, Hereditary cancer-predisposing syndrome |