| RS746313384 |
TNFSF11
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive osteopetrosis 2, Inborn genetic diseases |
| RS746314274 |
ZMIZ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746314593 |
APOA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypoalphalipoproteinemia, primary |
| RS746315218 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS746315507 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS746315718 |
CYP11B2
|
Health Risk |
Likely pathogenic |
— |
| RS746315830 |
DYSF
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Miyoshi muscular dystrophy 1 |
| RS746315995 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746317037 |
RYR1
|
Health Risk |
Pathogenic |
RYR1-related disorder, RYR1-related disorder |
| RS746317294 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Noonan syndrome 9 |
| RS746318136 |
POC1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 20, Inborn genetic diseases |
| RS746319045 |
XPC
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group C |
| RS746319505 |
CYP2U1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Hereditary spastic paraplegia |
| RS746319722 |
SATB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Chromosome 2q32-q33 deletion syndrome |
| RS746320156 |
LAMA5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746320191 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial meningioma, Hereditary cancer-predisposing syndrome |
| RS746320974 |
TOPORS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS746321506 |
TRIM32
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome, Sarcotubular myopathy |
| RS746322193 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Medulloblastoma, Gorlin syndrome |
| RS746322262 |
AGRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 8, Congenital myasthenic syndrome 8 |
| RS746322724 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS746323102 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Baller-Gerold syndrome |
| RS746323472 |
YY1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gabriele de Vries syndrome, Gabriele de Vries syndrome |
| RS746324091 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS746325928 |
BARD1
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS746328450 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, ankyrin-B-related |
| RS746328978 |
SYNE1
|
Health Risk |
Pathogenic |
Autosomal recessive ataxia, Beauce type |
| RS746329051 |
MIPEP
|
Health Risk |
Pathogenic |
— |
| RS746329317 |
SPG11
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 11, Hereditary spastic paraplegia 11 |
| RS746330518 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebrooculofacioskeletal syndrome 1, Cerebrooculofacioskeletal syndrome 1 |
| RS746331416 |
HPS3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 3, Hermansky-Pudlak syndrome 3 |
| RS746331438 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary diffuse gastric adenocarcinoma |
| RS746332288 |
BTD
|
Health Risk |
Likely pathogenic |
Biotinidase deficiency, Biotinidase deficiency |
| RS746332363 |
ACAT1
|
Health Risk |
Pathogenic |
Deficiency of acetyl-CoA acetyltransferase, Deficiency of acetyl-CoA acetyltransferase |
| RS746332433 |
AMPD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Pontocerebellar hypoplasia type 9 |
| RS746333044 |
CUL7
|
Health Risk |
Pathogenic/Likely pathogenic |
3M syndrome 1, 3M syndrome 1 |
| RS746333083 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS746335599 |
TBX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tetralogy of Fallot, DiGeorge syndrome |
| RS746336365 |
TRPV3
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated focal non-epidermolytic palmoplantar keratoderma, Isolated focal non-epidermolytic palmoplantar keratoderma |
| RS746338306 |
SZT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 18 |
| RS746339285 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS746339472 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS746339542 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS746340447 |
FANCE
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group E, Fanconi anemia complementation group E |
| RS746340627 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolfram syndrome 1, Wolfram syndrome 1 |
| RS746340772 |
IFT172
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 71, Short-rib thoracic dysplasia 10 with or without polydactyly |
| RS746341018 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Cardiovascular phenotype |
| RS746341112 |
NUP37
|
Health Risk |
Likely pathogenic |
Microcephaly 24, primary |
| RS746341454 |
UNC13D
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis 3 |
| RS746341530 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746341645 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS746342377 |
PLOD3
|
Health Risk |
Pathogenic |
— |
| RS746342893 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Adams-Oliver syndrome 5 |
| RS746343051 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746343857 |
EFEMP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cutis laxa, autosomal recessive |
| RS746344058 |
APOA4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746344900 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS746346292 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS746347634 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS746348793 |
PFKM
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type VII |
| RS746349613 |
AP5Z1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 48, Hereditary spastic paraplegia 48 |
| RS746350036 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS746351112 |
LCA5
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Leber congenital amaurosis 5 |
| RS746353565 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 10, Arrhythmogenic right ventricular cardiomyopathy |
| RS746353651 |
WT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilms tumor 1, Meacham syndrome |
| RS746354303 |
PLOD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, kyphoscoliotic type 1 |
| RS746354760 |
ADAMTS17
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani 4 syndrome, recessive |
| RS746355138 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Kabuki syndrome |
| RS746355340 |
MFAP5
|
Health Risk |
Pathogenic |
— |
| RS746355462 |
DPAGT1
|
Health Risk |
Conflicting classifications of pathogenicity |
DPAGT1-congenital disorder of glycosylation, Congenital myasthenic syndrome 13 |
| RS746355740 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, KBG syndrome |
| RS746356243 |
PNPT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined oxidative phosphorylation defect type 13, Inborn genetic diseases |
| RS746356513 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS746357519 |
TCOF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Treacher Collins syndrome 1 |
| RS746357591 |
GMPPB
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A14 |
| RS746358240 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS746358771 |
COL3A1
|
Health Risk |
Likely pathogenic |
— |
| RS746359389 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS746359399 |
RP1
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS746360455 |
TSHR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hyperthyroidism due to mutations in TSH receptor, Hypothyroidism due to TSH receptor mutations |
| RS746360476 |
MYLK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 1, Hypertrophic cardiomyopathy 1 |
| RS746360576 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Retinoblastoma |
| RS746360632 |
MPDZ
|
Health Risk |
Likely pathogenic |
Hydrocephalus, nonsyndromic |
| RS746361190 |
CNTNAP1
|
Health Risk |
Likely pathogenic |
Lethal congenital contracture syndrome 7, Lethal congenital contracture syndrome 7 |
| RS746361802 |
CFAP298
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 26, Primary ciliary dyskinesia 26 |
| RS74636274 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa 25 |
| RS746362740 |
ATP1A2
|
Health Risk |
Likely pathogenic |
Familial hemiplegic migraine, Familial hemiplegic migraine |
| RS746362966 |
GATA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Deafness-lymphedema-leukemia syndrome, Monocytopenia with susceptibility to infections |
| RS746364242 |
GRHPR
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary hyperoxaluria, type II |
| RS746364915 |
FDXR
|
Health Risk |
Likely pathogenic |
— |
| RS746364980 |
CLDN19
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal hypomagnesemia 5 with ocular involvement, Renal hypomagnesemia 5 with ocular involvement |
| RS746365230 |
PRF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, Aplastic anemia |
| RS746366131 |
CBS
|
Health Risk |
Conflicting classifications of pathogenicity |
HYPERHOMOCYSTEINEMIA, THROMBOTIC |
| RS746366461 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS746368198 |
ACADS
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of butyryl-CoA dehydrogenase, Deficiency of butyryl-CoA dehydrogenase |
| RS746368269 |
TRPV4
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease axonal type 2C, Charcot-Marie-Tooth disease axonal type 2C |
| RS746368304 |
DPYD
|
Health Risk |
Conflicting classifications of pathogenicity |
Dihydropyrimidine dehydrogenase deficiency, DPYD-related disorder |
| RS746369012 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 2 |
| RS746369588 |
CNNM2
|
Health Risk |
Pathogenic |
Hypomagnesemia, seizures |
| RS746370059 |
SCARB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myoclonic epilepsy, Inborn genetic diseases |