| RS746020725 |
BBS12
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 12 |
| RS74602141 |
ITGA2B
|
Health Risk |
Pathogenic |
Glanzmann thrombasthenia, Glanzmann thrombasthenia |
| RS746021869 |
PYGM
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type V |
| RS746022197 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS746022915 |
PPP1R12A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746023380 |
LOXHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746023653 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS746023979 |
TG
|
Health Risk |
Pathogenic |
— |
| RS746024122 |
PRKDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to DNA-PKcs deficiency, Severe combined immunodeficiency due to DNA-PKcs deficiency |
| RS746025177 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 2 |
| RS746026526 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group O, Breast-ovarian cancer |
| RS746026558 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Charcot-Marie-Tooth disease axonal type 2O |
| RS746026845 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746027915 |
MED13L
|
Health Risk |
Conflicting classifications of pathogenicity |
Dextro-looped transposition of the great arteries, Inborn genetic diseases |
| RS746028168 |
QARS1
|
Health Risk |
Pathogenic |
Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome, Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome |
| RS746028762 |
LRP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cenani-Lenz syndactyly syndrome, Congenital myasthenic syndrome 17 |
| RS746031226 |
SRCAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746031284 |
MEGF8
|
Health Risk |
Conflicting classifications of pathogenicity |
MEGF8-related Carpenter syndrome, Inborn genetic diseases |
| RS746031384 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS746032367 |
ASCC3
|
Health Risk |
Pathogenic |
Intellectual developmental disorder, autosomal recessive 81 |
| RS746032983 |
TRAPPC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spondyloepiphyseal dysplasia tarda, Spondyloepiphyseal dysplasia tarda |
| RS746033038 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS746033950 |
HIVEP2
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal dominant 43 |
| RS746035610 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, type 4 |
| RS746035909 |
SH2D1A
|
Health Risk |
Pathogenic |
X-linked lymphoproliferative disease due to SH2D1A deficiency, X-linked lymphoproliferative disease due to SH2D1A deficiency |
| RS746036083 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS746036349 |
EPG5
|
Health Risk |
Pathogenic/Likely pathogenic |
Vici syndrome, Vici syndrome |
| RS746036694 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal dominant 2 |
| RS746036918 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS746037337 |
A2ML1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS74603784 |
PAH
|
Health Risk |
Likely pathogenic |
Phenylketonuria, Inborn genetic diseases |
| RS746037872 |
GRN
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis 11, GRN-related frontotemporal lobar degeneration with Tdp43 inclusions |
| RS746037899 |
SGSH
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis, MPS-III-A |
| RS746040003 |
RASA3
|
Health Risk |
Pathogenic |
Short stature, Short stature |
| RS746040843 |
GRIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal dominant |
| RS746043871 |
PPT1
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis 1, Neuronal ceroid lipofuscinosis 1 |
| RS746044783 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Tuberous sclerosis syndrome |
| RS746045424 |
CEP164
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 15, Nephronophthisis 15 |
| RS746045584 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS746046215 |
SLC26A4
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Pendred syndrome |
| RS746046225 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Collagen 6-related myopathy |
| RS746047600 |
LRP2
|
Health Risk |
Pathogenic |
— |
| RS746047636 |
ELOVL4
|
Health Risk |
Pathogenic |
Congenital ichthyosis-intellectual disability-spastic quadriplegia syndrome, Congenital ichthyosis-intellectual disability-spastic quadriplegia syndrome |
| RS746049858 |
DNAH1
|
Health Risk |
Pathogenic/Likely pathogenic |
Spermatogenic failure 18, Ciliary dyskinesia |
| RS746050475 |
GJC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, GJC2-related disorder |
| RS746050594 |
RAD21
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Cornelia de Lange syndrome 4 |
| RS746050665 |
TYRP1
|
Health Risk |
Pathogenic |
— |
| RS746051220 |
MYO15A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS746051777 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746052951 |
ADA
|
Health Risk |
Likely pathogenic |
Severe combined immunodeficiency, autosomal recessive |
| RS746053039 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746053679 |
SPG7
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 7, Early-onset progressive neurodegeneration-blindness-ataxia-spasticity syndrome |
| RS746053763 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa dystrophica, Recessive dystrophic epidermolysis bullosa |
| RS746054643 |
PANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pigmentary pallidal degeneration, Pigmentary pallidal degeneration |
| RS746055240 |
SLC13A5
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 25 |
| RS746055250 |
SCN11A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory and autonomic neuropathy type 7, Familial episodic pain syndrome with predominantly lower limb involvement |
| RS746055369 |
MYO3A
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 30, Autosomal recessive nonsyndromic hearing loss 30 |
| RS746055479 |
NOD2
|
Health Risk |
Pathogenic |
Behcet disease, Behcet disease |
| RS746056280 |
COL7A1
|
Health Risk |
Pathogenic |
Recessive dystrophic epidermolysis bullosa, Epidermolysis bullosa dystrophica |
| RS746056671 |
GARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease |
| RS746057093 |
AAAS
|
Health Risk |
Pathogenic/Likely pathogenic |
Glucocorticoid deficiency with achalasia, Glucocorticoid deficiency with achalasia |
| RS746057464 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS746057710 |
TBC1D24
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 1 |
| RS746058354 |
UBE3B
|
Health Risk |
Pathogenic/Likely pathogenic |
Oculocerebrofacial syndrome, Kaufman type |
| RS746058773 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS746059113 |
NPHP3
|
Health Risk |
Pathogenic |
Nephronophthisis 3, Nephronophthisis 3 |
| RS746059124 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 2, Ullrich congenital muscular dystrophy 2 |
| RS746059690 |
QRICH1
|
Health Risk |
Pathogenic |
Ververi-Brady syndrome, Ververi-Brady syndrome |
| RS746059848 |
ATP8B1
|
Health Risk |
Pathogenic |
— |
| RS746060136 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS746060505 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS746060762 |
SCN2A
|
Health Risk |
Pathogenic |
Complex neurodevelopmental disorder, Inborn genetic diseases |
| RS746060886 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS746063269 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS746063338 |
FAM20A
|
Health Risk |
Pathogenic/Likely pathogenic |
Amelogenesis imperfecta type 1G, Amelogenesis imperfecta type 1G |
| RS746064480 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS746067447 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS746067825 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS746067865 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS746068577 |
PRDM5
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS746068882 |
KIAA0753
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome, Jeune thoracic dystrophy |
| RS746069709 |
TTLL5
|
Health Risk |
Pathogenic |
— |
| RS746069907 |
HPS6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 6, Hermansky-Pudlak syndrome 6 |
| RS746069957 |
TEK
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple cutaneous and mucosal venous malformations, Inborn genetic diseases |
| RS746070443 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCA4-related disorder, ABCA4-related disorder |
| RS746070652 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS746070910 |
ABCA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Interstitial lung disease due to ABCA3 deficiency, Interstitial lung disease due to ABCA3 deficiency |
| RS746071223 |
VCAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Wagner disease, Wagner disease |
| RS74607124 |
FLVCR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Posterior column ataxia-retinitis pigmentosa syndrome, Posterior column ataxia-retinitis pigmentosa syndrome |
| RS746071518 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS746071929 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Usher syndrome type 2A |
| RS746071945 |
REDIC1
|
Health Risk |
Pathogenic |
Spermatogenic Failure, Spermatogenic Failure |
| RS746072884 |
PLOD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS746073643 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS746074230 |
EPG5
|
Health Risk |
Likely pathogenic |
EPG5-related disorder, EPG5-related disorder |
| RS746075271 |
UBQLN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 15, Amyotrophic lateral sclerosis type 15 |
| RS746075396 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746075428 |
CAPN3
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy |
| RS746075630 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS746076695 |
EOGT
|
Health Risk |
Likely pathogenic |
Adams-Oliver syndrome 4, Adams-Oliver syndrome 4 |