| RS745369888 |
RDH12
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 13, Leber congenital amaurosis 13 |
| RS745370910 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS745371873 |
USH2A
|
Health Risk |
Pathogenic |
— |
| RS745371874 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS745371972 |
PRG4
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS745372938 |
TRIP11
|
Health Risk |
Likely pathogenic |
Achondrogenesis, type IA |
| RS745373565 |
DLX3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745374335 |
DSCAM
|
Health Risk |
Conflicting classifications of pathogenicity |
DSCAM-related disorder, Autism |
| RS745374448 |
F7
|
Health Risk |
Pathogenic |
F7-related disorder, Congenital factor VII deficiency |
| RS745374795 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Kleefstra syndrome 1 |
| RS745375312 |
PFKM
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type VII |
| RS745375504 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CHD8-related disorder |
| RS745376275 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS745376502 |
COL4A2
|
Health Risk |
Likely pathogenic |
— |
| RS745377913 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypocalciuric hypercalcemia, Autosomal dominant hypocalcemia 1 |
| RS745378093 |
ECEL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Distal arthrogryposis type 5D, Distal arthrogryposis type 5D |
| RS745378130 |
TBX5
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic valve disease 2, Cardiovascular phenotype |
| RS745378351 |
SLC26A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 61, SLC26A5-related disorder |
| RS745378416 |
SCN1A
|
Health Risk |
Pathogenic/Likely pathogenic |
Early-infantile DEE, Early-infantile DEE |
| RS745379131 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Smith-Magenis syndrome, RAI1-related disorder |
| RS745380273 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745380962 |
DNMT3A
|
Health Risk |
Likely pathogenic |
Multiple myeloma, Multiple myeloma |
| RS745381057 |
FLNB
|
Health Risk |
Likely pathogenic |
— |
| RS745381842 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS745381915 |
COL27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745382051 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS745382488 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate B, Charcot-Marie-Tooth disease dominant intermediate B |
| RS745382616 |
PEX6
|
Health Risk |
Pathogenic |
Peroxisome biogenesis disorder, Heimler syndrome 2 |
| RS745382789 |
CABP4
|
Health Risk |
Pathogenic |
Cone-rod synaptic disorder, congenital nonprogressive |
| RS745383145 |
NTHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, NTHL1-related disorder |
| RS745383210 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Rhabdoid tumor predisposition syndrome 2 |
| RS745385484 |
PNKP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS745385503 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS745385522 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Brittle cornea syndrome 1, Cardiovascular phenotype |
| RS745386414 |
SLC17A5
|
Health Risk |
Pathogenic |
Salla disease, Salla disease |
| RS745386663 |
GLB1
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-IV-B |
| RS745389962 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS745391227 |
GRN
|
Health Risk |
Conflicting classifications of pathogenicity |
GRN-related frontotemporal lobar degeneration with Tdp43 inclusions, Neuronal ceroid lipofuscinosis 11 |
| RS745391240 |
COPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoimmune interstitial lung disease-arthritis syndrome, Inborn genetic diseases |
| RS745391514 |
SEPTIN9
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745392080 |
HOXB13
|
Health Risk |
Conflicting classifications of pathogenicity |
Prostate cancer, hereditary |
| RS745392382 |
CCDC78
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myopathy with internal nuclei and atypical cores, Inborn genetic diseases |
| RS745392621 |
CRLF1
|
Health Risk |
Likely pathogenic |
Cold-induced sweating syndrome 1, Cold-induced sweating syndrome 1 |
| RS745394044 |
HACE1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745394212 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS745394467 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Spinocerebellar ataxia |
| RS745394881 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS745395767 |
GPSM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Chudley-McCullough syndrome, Chudley-McCullough syndrome |
| RS745396297 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS745396398 |
CHD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy 94, Developmental and epileptic encephalopathy 94 |
| RS745396554 |
SON
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745399096 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745399748 |
NDUFA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex I deficiency, nuclear type 1 |
| RS745399967 |
COL13A1
|
Health Risk |
Likely pathogenic |
— |
| RS745401772 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS745403938 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS745404241 |
ASS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Citrullinemia type I, Citrullinemia |
| RS745404679 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS745404712 |
VPS13B
|
Health Risk |
Likely pathogenic |
Cohen syndrome, Cohen syndrome |
| RS745404766 |
EVC2
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS745406929 |
KMT2C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745407557 |
ADAMTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS745407845 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS745408471 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS745408649 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS745409162 |
RTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS745409628 |
PLOD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Ehlers-Danlos syndrome, kyphoscoliotic type 1 |
| RS745410848 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS745411817 |
CTNNA1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS745413532 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 1 |
| RS745413543 |
RPGRIP1L
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome 7, Meckel-Gruber syndrome |
| RS745413738 |
PCNT
|
Health Risk |
Pathogenic |
— |
| RS745413783 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, arthrochalasia type |
| RS745413794 |
CYP4V2
|
Health Risk |
Pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS745414155 |
MYCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, MYCN-related disorder |
| RS745414252 |
ABCD4
|
Health Risk |
Likely pathogenic |
Cobalamin C disease, Methylmalonic acidemia with homocystinuria |
| RS745414764 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, Cystic fibrosis |
| RS745414854 |
TSC2
|
Health Risk |
Pathogenic |
— |
| RS745417882 |
NEXMIF
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked intellectual disability, Cantagrel type |
| RS745418167 |
SPAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 28, Primary ciliary dyskinesia |
| RS745418679 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS745418947 |
POLR3A
|
Health Risk |
Pathogenic/Likely pathogenic |
Leukodystrophy, hypomyelinating |
| RS745418960 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS745420110 |
NEB
|
Health Risk |
Pathogenic |
— |
| RS745420974 |
SZT2
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 18 |
| RS745421590 |
FANCM
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, FANCM-related disorder |
| RS745422316 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS745422404 |
TTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Carpal tunnel syndrome 1 |
| RS745422941 |
CRB1
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 8, Retinitis pigmentosa 12 |
| RS745424307 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS745425169 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS745425759 |
TP53
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Li-Fraumeni syndrome 1 |
| RS745426479 |
ALG6
|
Health Risk |
Pathogenic/Likely pathogenic |
ALG6-congenital disorder of glycosylation 1C, ALG6-congenital disorder of glycosylation 1C |
| RS745427463 |
PRPH2
|
Health Risk |
Likely pathogenic |
— |
| RS745427593 |
TJP2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745427943 |
GAA
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type II |
| RS745428229 |
RPGR
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Retinitis pigmentosa 3 |
| RS745429365 |
DDX3X
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745432268 |
DHTKD1
|
Health Risk |
Pathogenic |
2-aminoadipic 2-oxoadipic aciduria, 2-aminoadipic 2-oxoadipic aciduria |
| RS745432667 |
MPI
|
Health Risk |
Pathogenic/Likely pathogenic |
MPI-congenital disorder of glycosylation, MPI-congenital disorder of glycosylation |