| RS745570426 |
PRKAR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Carney complex, type 1 |
| RS745571507 |
PCCA
|
Health Risk |
Pathogenic |
Propionic acidemia, Propionic acidemia |
| RS745571683 |
CDH23
|
Health Risk |
Pathogenic/Likely pathogenic |
Rare genetic deafness, Usher syndrome type 1 |
| RS745571736 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS745571898 |
FSIP2
|
Health Risk |
Likely pathogenic |
Spermatogenic failure 34, Spermatogenic failure 34 |
| RS745573222 |
OCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tyrosinase-positive oculocutaneous albinism, OCA2-related disorder |
| RS745573372 |
INVS
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Nephronophthisis |
| RS745574120 |
EYS
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 25, Retinitis pigmentosa 25 |
| RS745574548 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745574784 |
FAM161A
|
Health Risk |
Pathogenic |
— |
| RS745575483 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy 5, Developmental and epileptic encephalopathy |
| RS745576236 |
TNPO3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant limb-girdle muscular dystrophy type 1F, Inborn genetic diseases |
| RS745578045 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS745578837 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745580319 |
AP4B1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 47, Hereditary spastic paraplegia 47 |
| RS745580526 |
SLC2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
GLUT1 deficiency syndrome 1, autosomal recessive |
| RS745580589 |
MCCC1
|
Health Risk |
Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 1 deficiency, 3-methylcrotonyl-CoA carboxylase 1 deficiency |
| RS745582203 |
G6PC3
|
Health Risk |
Pathogenic |
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency, Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency |
| RS745583389 |
DLL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745583559 |
HTT
|
Health Risk |
Pathogenic |
— |
| RS745584505 |
MARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency |
| RS745585519 |
DMD
|
Health Risk |
Pathogenic |
Becker muscular dystrophy, Duchenne muscular dystrophy |
| RS745585873 |
CLRN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 61, Retinitis pigmentosa 61 |
| RS745586435 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS745587834 |
TLCD3B
|
Health Risk |
Pathogenic |
Cone-rod dystrophy 22, Cone-rod dystrophy 22 |
| RS745590123 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS745590324 |
TERT
|
Health Risk |
Likely pathogenic |
Dyskeratosis congenita, Dyskeratosis congenita |
| RS745590426 |
ATP6V0A2
|
Health Risk |
Pathogenic/Likely pathogenic |
ALG9 congenital disorder of glycosylation, Cutis laxa |
| RS745590718 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autosomal dominant nocturnal frontal lobe epilepsy 5 |
| RS745590895 |
SLC26A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple epiphyseal dysplasia type 4, Achondrogenesis |
| RS745592082 |
DNAH8
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS745592705 |
CNGA3
|
Health Risk |
Pathogenic |
Achromatopsia 2, Achromatopsia 2 |
| RS745594160 |
APRT
|
Health Risk |
Conflicting classifications of pathogenicity |
Adenine phosphoribosyltransferase deficiency, Adenine phosphoribosyltransferase deficiency |
| RS745594303 |
HPDL
|
Health Risk |
Likely pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS745594354 |
NANS
|
Health Risk |
Likely pathogenic |
Spondyloepimetaphyseal dysplasia, Genevieve type |
| RS745594874 |
PRRT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic kinesigenic dyskinesia, Inborn genetic diseases |
| RS745595242 |
DHCR7
|
Health Risk |
Conflicting classifications of pathogenicity |
Smith-Lemli-Opitz syndrome, Inborn genetic diseases |
| RS745595462 |
GAD1
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy 89, Developmental and epileptic encephalopathy 89 |
| RS745595833 |
YARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Myopathy, lactic acidosis |
| RS745597127 |
NHS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Nance-Horan syndrome |
| RS745597204 |
FRAS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Fraser syndrome 1, Congenital anomaly of kidney and urinary tract |
| RS745597535 |
ZNF423
|
Health Risk |
Conflicting classifications of pathogenicity |
Abnormal brain morphology, Nephronophthisis 14 |
| RS745598716 |
NUP188
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745598788 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, PCNT-related disorder |
| RS745599370 |
SGCG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745599611 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS745601745 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS745603321 |
WDR19
|
Health Risk |
Likely pathogenic |
Jeune thoracic dystrophy, Asphyxiating thoracic dystrophy 5 |
| RS745603844 |
CEP135
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS745604189 |
CD36
|
Health Risk |
Conflicting classifications of pathogenicity |
Platelet-type bleeding disorder 10, Platelet-type bleeding disorder 10 |
| RS745604417 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS745604653 |
MLYCD
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of malonyl-CoA decarboxylase, MLYCD-related disorder |
| RS745607005 |
PDHA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyruvate dehydrogenase E1-alpha deficiency, Inborn genetic diseases |
| RS745608560 |
LRBA
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to LRBA deficiency, See cases |
| RS745609349 |
SP7
|
Health Risk |
Likely pathogenic |
Osteogenesis imperfecta type 12, Osteogenesis imperfecta type 12 |
| RS745609580 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS745609654 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS745610059 |
GTPBP2
|
Health Risk |
Pathogenic |
Jaberi-Elahi syndrome, Jaberi-Elahi syndrome |
| RS745612436 |
PEX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 1A (Zellweger), Zellweger spectrum disorders |
| RS745612845 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS745613994 |
FIG4
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 11, Charcot-Marie-Tooth disease type 4J |
| RS745614158 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745614655 |
MYH14
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745616771 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS745617052 |
RTTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745617145 |
FH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, FH-related disorder |
| RS745617885 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 10 |
| RS745618641 |
DLL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745619253 |
COQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745619898 |
GSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Finnish type amyloidosis, Finnish type amyloidosis |
| RS745620101 |
GALC
|
Health Risk |
Pathogenic/Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS745622138 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Peutz-Jeghers syndrome |
| RS745622612 |
USH1C
|
Health Risk |
Pathogenic |
Usher syndrome type 1C, Autosomal recessive nonsyndromic hearing loss 18A |
| RS745624228 |
TPRN
|
Health Risk |
Pathogenic |
— |
| RS745624953 |
ARG1
|
Health Risk |
Pathogenic/Likely pathogenic |
Arginase deficiency, Arginase deficiency |
| RS745625855 |
MYH14
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 4A, Autosomal dominant nonsyndromic hearing loss 4A |
| RS745626132 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS745626388 |
PC
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyruvate carboxylase deficiency, Pyruvate carboxylase deficiency |
| RS745626507 |
CYP11B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Corticosterone methyl oxidase type II deficiency, Corticosterone 18-monooxygenase deficiency |
| RS745626835 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS745627109 |
UNC45A
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteootohepatoenteric syndrome, Osteootohepatoenteric syndrome |
| RS745627738 |
EVC
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS745627867 |
RECQL4
|
Health Risk |
Pathogenic |
Baller-Gerold syndrome, Baller-Gerold syndrome |
| RS745628463 |
SLC34A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive hypophosphatemic bone disease, Autosomal recessive hypophosphatemic bone disease |
| RS745629936 |
IVD
|
Health Risk |
Likely pathogenic |
Isovaleryl-CoA dehydrogenase deficiency, Isovaleryl-CoA dehydrogenase deficiency |
| RS745630370 |
TMEM126B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745630993 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS745632282 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS745633046 |
ACSF3
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS745633496 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Stickler syndrome type 1, COL2A1-related disorder |
| RS745638170 |
PACS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schuurs-Hoeijmakers syndrome, Schuurs-Hoeijmakers syndrome |
| RS745638189 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, PTEN hamartoma tumor syndrome |
| RS745638752 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial colorectal cancer type X |
| RS745638837 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS745639179 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS745639930 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS745640577 |
KL
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumoral calcinosis, hyperphosphatemic |
| RS745640752 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS745640786 |
DMD
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Duchenne muscular dystrophy |
| RS745640894 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, Donnai-Barrow syndrome |