| RS745698076 |
IFT172
|
Health Risk |
Conflicting classifications of pathogenicity |
IFT172-related disorder, Short-rib thoracic dysplasia 10 with or without polydactyly |
| RS745699870 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS745700206 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS745700518 |
GTPBP3
|
Health Risk |
Pathogenic |
— |
| RS745700983 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
6 conditions, Dilated cardiomyopathy 1G |
| RS745702141 |
DUOX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Thyroid dyshormonogenesis 6, Thyroid dyshormonogenesis 6 |
| RS745702167 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Idiopathic hypereosinophilic syndrome |
| RS745702205 |
MCPH1
|
Health Risk |
Likely pathogenic |
Microcephaly 1, primary |
| RS745704046 |
CBS
|
Health Risk |
Conflicting classifications of pathogenicity |
Classic homocystinuria, Homocystinuria |
| RS745704336 |
TOGARAM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Joubert syndrome 37 |
| RS745704627 |
PROM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 41, Retinal dystrophy |
| RS745705515 |
TET2
|
Health Risk |
Pathogenic |
— |
| RS745705522 |
ARX
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 1 |
| RS745705652 |
HMBS
|
Health Risk |
Conflicting classifications of pathogenicity |
Acute intermittent porphyria, Acute intermittent porphyria |
| RS745708044 |
FOXN1
|
Health Risk |
Pathogenic |
T-cell immunodeficiency, congenital alopecia |
| RS745708104 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS745709409 |
SLC25A15
|
Health Risk |
Likely pathogenic |
Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome, Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome |
| RS745710633 |
CCM2
|
Health Risk |
Pathogenic/Likely pathogenic |
Cerebral cavernous malformation 2, Cerebral cavernous malformation 2 |
| RS745711468 |
LMX1B
|
Health Risk |
Pathogenic |
— |
| RS745711486 |
COQ8A
|
Health Risk |
Pathogenic |
— |
| RS745711489 |
A2ML1
|
Health Risk |
Conflicting classifications of pathogenicity |
A2ML1-related disorder, A2ML1-related disorder |
| RS745712429 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Wolfram syndrome 1 |
| RS745712472 |
KRABD4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745712829 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS745713189 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS745714537 |
DNMT3A
|
Health Risk |
Likely pathogenic |
— |
| RS745714733 |
ETFDH
|
Health Risk |
Pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS745715225 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 27 |
| RS74571530 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, CFTR-related disorder |
| RS745715484 |
SELENON
|
Health Risk |
Pathogenic/Likely pathogenic |
Eichsfeld type congenital muscular dystrophy, Eichsfeld type congenital muscular dystrophy |
| RS745715995 |
SCNN1G
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism, type IB1 |
| RS745716104 |
COL6A2
|
Health Risk |
Pathogenic |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS745717087 |
SKI
|
Health Risk |
Conflicting classifications of pathogenicity |
Shprintzen-Goldberg syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS745717503 |
TRPC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 2, Focal segmental glomerulosclerosis 2 |
| RS745718158 |
GFM1
|
Health Risk |
Pathogenic |
Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1, Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1 |
| RS745718831 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS745719077 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
6 conditions, 6 conditions |
| RS745719906 |
ACTL7A
|
Health Risk |
Pathogenic |
Male infertility with normal semen parameters, Male infertility with normal semen parameters |
| RS745720102 |
NEXMIF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745720217 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS745721296 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS745722568 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS745722569 |
FLG
|
Health Risk |
Pathogenic/Likely pathogenic |
Ichthyosis vulgaris, Ichthyosis vulgaris |
| RS745723771 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Inborn genetic diseases |
| RS745725479 |
PNPLA6
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 39, Hereditary spastic paraplegia 39 |
| RS745725913 |
SMARCA5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745726033 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Genitopatellar syndrome, Genitopatellar syndrome |
| RS745726293 |
GATA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Deafness-lymphedema-leukemia syndrome, Monocytopenia with susceptibility to infections |
| RS745726816 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745727200 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group J |
| RS745727347 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS745727504 |
HADH
|
Health Risk |
Pathogenic/Likely pathogenic/Likely risk allele |
Deficiency of 3-hydroxyacyl-CoA dehydrogenase, Hyperinsulinemic hypoglycemia |
| RS745727857 |
COL9A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Connective tissue disorder |
| RS745730439 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS745730969 |
CARD9
|
Health Risk |
Conflicting classifications of pathogenicity |
Predisposition to invasive fungal disease due to CARD9 deficiency, Inborn genetic diseases |
| RS745731000 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS74573309 |
ADGRG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bilateral frontoparietal polymicrogyria, Bilateral frontoparietal polymicrogyria |
| RS745733410 |
MED17
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745734653 |
LOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS745734847 |
LSS
|
Health Risk |
Pathogenic |
Hypotrichosis 14, Alopecia-intellectual disability syndrome 4 |
| RS745735883 |
TUBGCP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745736928 |
EPG5
|
Health Risk |
Conflicting classifications of pathogenicity |
Vici syndrome, Inborn genetic diseases |
| RS745737815 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS745738301 |
CAMTA1
|
Health Risk |
Pathogenic |
— |
| RS745738318 |
EXT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Exostoses, multiple |
| RS745738628 |
POMT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1 |
| RS74574054 |
HLCS
|
Health Risk |
Conflicting classifications of pathogenicity |
Holocarboxylase synthetase deficiency, Holocarboxylase synthetase deficiency |
| RS745740862 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS745740932 |
SACS
|
Health Risk |
Pathogenic/Likely pathogenic |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS745740974 |
GAMT
|
Health Risk |
Likely pathogenic |
Cerebral creatine deficiency syndrome, Deficiency of guanidinoacetate methyltransferase |
| RS745741473 |
RPGRIP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Cone-rod dystrophy 13 |
| RS745741842 |
SNAP25
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 18, SNAP25-related disorder |
| RS745741888 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS745741960 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS745742009 |
DOCK6;DOCK6-AS1
|
Health Risk |
Likely pathogenic |
Hypercholanemia, familial 1 |
| RS745742289 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS745742429 |
LONP1
|
Health Risk |
Conflicting classifications of pathogenicity |
CODAS syndrome, CODAS syndrome |
| RS745743634 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS745743780 |
CTSA
|
Health Risk |
Pathogenic |
Combined deficiency of sialidase AND beta galactosidase, Combined deficiency of sialidase AND beta galactosidase |
| RS745743884 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Ehlers-Danlos syndrome |
| RS745744124 |
B4GALNT1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 26, Inborn genetic diseases |
| RS745745237 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745746091 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS745747228 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS745748213 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant centronuclear myopathy, Charcot-Marie-Tooth disease dominant intermediate B |
| RS745750156 |
CEP78
|
Health Risk |
Pathogenic |
Cone-rod dystrophy and hearing loss 1, Familial pancreatic carcinoma |
| RS745750549 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS74575103 |
G6PD
|
Health Risk |
Pathogenic/Likely pathogenic |
G6PD deficiency, Anemia |
| RS745751151 |
TRDN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS745751553 |
TP53
|
Health Risk |
Conflicting classifications of pathogenicity |
Li-Fraumeni syndrome, Li-Fraumeni syndrome 1 |
| RS745753810 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS745754277 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS745754388 |
EPG5
|
Health Risk |
Likely pathogenic |
Vici syndrome, Vici syndrome |
| RS745754668 |
SETD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual disability-facial dysmorphism syndrome due to SETD5 haploinsufficiency |
| RS745755437 |
GDF9
|
Health Risk |
Pathogenic |
Premature ovarian failure 14, Premature ovarian failure 14 |
| RS745755917 |
DNAI2
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 9 |
| RS745756308 |
HNMT
|
Health Risk |
Likely pathogenic |
Intellectual disability, autosomal recessive 51 |
| RS745757264 |
AGL
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS745758403 |
CACNA1G
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745758977 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |