| RS745507744 |
P3H2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS74550830 |
LARGE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A6 |
| RS745508510 |
PGM3
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 23, Severe combined immunodeficiency disease |
| RS745508761 |
SLX4
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Hereditary cancer |
| RS745508762 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 7 |
| RS745509085 |
POMT1
|
Health Risk |
Pathogenic |
Walker-Warburg congenital muscular dystrophy, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS745509632 |
SORD
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS745510765 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS74551128 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, ivacaftor response - Efficacy |
| RS745511282 |
NAGS
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperammonemia, type III |
| RS745511715 |
GLIS3
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal diabetes mellitus with congenital hypothyroidism, Inborn genetic diseases |
| RS745511810 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy |
| RS745512079 |
LAMC2
|
Health Risk |
Pathogenic |
Junctional epidermolysis bullosa gravis of Herlitz, Junctional epidermolysis bullosa gravis of Herlitz |
| RS745512712 |
LAMA1
|
Health Risk |
Pathogenic |
— |
| RS745516122 |
SPART
|
Health Risk |
Pathogenic |
— |
| RS745516434 |
FLG
|
Health Risk |
Pathogenic/Likely pathogenic |
FLG-related disorder, FLG-related disorder |
| RS745517212 |
CAD
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile epileptic dyskinetic encephalopathy, Infantile epileptic dyskinetic encephalopathy |
| RS745517517 |
GNE
|
Health Risk |
Pathogenic |
GNE myopathy, Sialuria |
| RS745518012 |
MKS1
|
Health Risk |
Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS745518051 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Monogenic diabetes, Alstrom syndrome |
| RS745519889 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS745520295 |
NDRG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4D, Charcot-Marie-Tooth disease type 4 |
| RS745521166 |
TCIRG1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745521288 |
PGAP2
|
Health Risk |
Likely pathogenic |
Hyperphosphatasia with intellectual disability syndrome 3, Hyperphosphatasia with intellectual disability syndrome 3 |
| RS745522018 |
COL9A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Melanoma, Melanoma |
| RS745522483 |
CEP290
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis, Meckel-Gruber syndrome |
| RS745522921 |
PAX9
|
Health Risk |
Likely pathogenic |
Tooth agenesis, selective |
| RS745522949 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS745523154 |
GALNS
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-IV-A |
| RS745523374 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS745524993 |
SLC6A19
|
Health Risk |
Likely pathogenic |
Neutral 1 amino acid transport defect, Neutral 1 amino acid transport defect |
| RS745525261 |
DNAH17
|
Health Risk |
Likely pathogenic |
DNAH17-related disorder, DNAH17-related disorder |
| RS74552543 |
CNNM4
|
Health Risk |
Pathogenic |
Jalili syndrome, Jalili syndrome |
| RS745526087 |
SKIC2
|
Health Risk |
Pathogenic |
— |
| RS745526568 |
NEK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Short-rib thoracic dysplasia 6 with or without polydactyly |
| RS745528043 |
LRBA
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to LRBA deficiency, Inborn genetic diseases |
| RS745528502 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS745528772 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS745528957 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS745529713 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS745529755 |
SLC6A1
|
Health Risk |
Pathogenic |
Epilepsy with myoclonic atonic seizures, Inborn genetic diseases |
| RS745530308 |
PRICKLE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myoclonic epilepsy, Progressive myoclonic epilepsy type 5 |
| RS745530646 |
YARS1
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS745531507 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, KBG syndrome |
| RS745532481 |
COL9A1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS745533713 |
PALB2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS745534256 |
SCO2
|
Health Risk |
Pathogenic |
— |
| RS745534850 |
IGHMBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive distal spinal muscular atrophy 1, Charcot-Marie-Tooth disease axonal type 2S |
| RS745538859 |
GRIN2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745538883 |
BLM
|
Health Risk |
Likely pathogenic |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS745539518 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Retinal dystrophy |
| RS74553953 |
CEP152
|
Health Risk |
Conflicting classifications of pathogenicity |
Seckel syndrome 5, Microcephaly 9 |
| RS745539599 |
POLG
|
Health Risk |
Likely pathogenic |
Mitochondrial DNA depletion syndrome, Mitochondrial DNA depletion syndrome |
| RS745539706 |
SLC6A5
|
Health Risk |
Pathogenic |
Hyperekplexia 3, Hyperekplexia 3 |
| RS745541294 |
CDK5RAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 3, primary |
| RS745542691 |
GPR179
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745543661 |
WARS2
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder, mitochondrial |
| RS745543829 |
SLC34A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autosomal recessive hypophosphatemic bone disease |
| RS745544039 |
ABCA4
|
Health Risk |
Pathogenic |
— |
| RS745544108 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
DDX41-related hematologic malignancy predisposition syndrome, Inborn genetic diseases |
| RS745544854 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS745544964 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS745545200 |
AHNAK2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745546266 |
ATP8B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial intrahepatic cholestasis type 1, Progressive familial intrahepatic cholestasis type 1 |
| RS745546363 |
SRCAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental delay |
| RS745547578 |
CPT2
|
Health Risk |
Pathogenic |
Carnitine palmitoyltransferase II deficiency, Carnitine palmitoyltransferase II deficiency |
| RS745547693 |
COL9A3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745547797 |
RHOBTB2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745549446 |
PYCR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cutis laxa, Cutis laxa |
| RS745549628 |
TPM2
|
Health Risk |
Likely pathogenic |
Arthrogryposis, distal |
| RS745551441 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, Inborn genetic diseases |
| RS745552747 |
RP1
|
Health Risk |
Pathogenic |
— |
| RS745552903 |
DNAH1
|
Health Risk |
Likely pathogenic |
Spermatogenic failure 18, Spermatogenic failure 18 |
| RS745553087 |
MSH3
|
Health Risk |
Likely pathogenic |
Endometrial carcinoma, Endometrial carcinoma |
| RS745553184 |
UQCRC2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745553724 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS745554323 |
FIG4
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Charcot-Marie-Tooth disease type 4 |
| RS745554420 |
MID1
|
Health Risk |
Pathogenic |
X-linked Opitz G/BBB syndrome, X-linked Opitz G/BBB syndrome |
| RS745555171 |
CRYBA1
|
Health Risk |
Likely pathogenic |
Cataract 10 multiple types, Cataract 10 multiple types |
| RS745555433 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS745557293 |
CNGB3
|
Health Risk |
Pathogenic |
Achromatopsia 3, Achromatopsia 3 |
| RS745557512 |
ACADVL
|
Health Risk |
Conflicting classifications of pathogenicity |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS74555752 |
RNASEH2B
|
Health Risk |
Pathogenic/Likely pathogenic |
Aicardi-Goutieres syndrome 2, Aicardi-Goutieres syndrome 2 |
| RS745557569 |
ABCB11
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial intrahepatic cholestasis type 2, Benign recurrent intrahepatic cholestasis type 2 |
| RS745557874 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS745558003 |
EVC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS745559136 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS745559323 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS745563552 |
AQP5
|
Health Risk |
Likely pathogenic |
Palmoplantar keratoderma, Bothnian type |
| RS745563711 |
PC
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyruvate carboxylase deficiency, Pyruvate carboxylase deficiency |
| RS745563920 |
BRAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal-onset encephalopathy with rigidity and seizures, Inborn genetic diseases |
| RS745564692 |
SLC35D1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schneckenbecken dysplasia, Schneckenbecken dysplasia |
| RS745565332 |
GPT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Glutamate pyruvate transaminase 2 deficiency, Hereditary spastic paraplegia 73 |
| RS745565855 |
NDUFS6
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex I deficiency, nuclear type 1 |
| RS745566147 |
CCDC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745566747 |
COL27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS74556809 |
TREX1
|
Health Risk |
Likely pathogenic |
Aicardi-Goutieres syndrome 1, Chilblain lupus 1 |
| RS745568808 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fibrochondrogenesis 2, Otospondylomegaepiphyseal dysplasia |
| RS745568821 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS745569223 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Central core myopathy |