| RS74503862 |
NRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, NRIP1-related disorder |
| RS74508995 |
KCNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Jervell and Lange-Nielsen syndrome 2, Long QT syndrome 5 |
| RS74516571 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, ABCA4-related disorder |
| RS74517001 |
UNC80
|
Health Risk |
Pathogenic |
UNC80-related disorder, UNC80-related disorder |
| RS74518351 |
OTC
|
Health Risk |
Likely pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS745305837 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Inborn genetic diseases |
| RS745305844 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS745305932 |
SLC25A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiomyopathy-hypotonia-lactic acidosis syndrome, Cardiomyopathy-hypotonia-lactic acidosis syndrome |
| RS745306528 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS745307359 |
RAD51D
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast and/or ovarian cancer, Breast-ovarian cancer |
| RS745308120 |
NRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745308973 |
GNAT2
|
Health Risk |
Pathogenic |
Achromatopsia 4, Achromatopsia |
| RS745310138 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, POLG-related disorder |
| RS745312507 |
GSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745312608 |
CLN5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis, Inborn genetic diseases |
| RS745313320 |
IDH3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 46, Retinitis pigmentosa 46 |
| RS745313899 |
PRSS37
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745314195 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Genitopatellar syndrome, Blepharophimosis - intellectual disability syndrome |
| RS745316066 |
ENG
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary hemorrhagic telangiectasia, Telangiectasia |
| RS745318365 |
COL7A1
|
Health Risk |
Pathogenic |
COL7A1-related disorder, COL7A1-related disorder |
| RS745319034 |
SLC7A9
|
Health Risk |
Pathogenic |
Cystinuria, SLC7A9-related disorder |
| RS745319635 |
SGSH
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis, MPS-III-A |
| RS745319720 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS745320719 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile cortical hyperostosis, Osteogenesis imperfecta |
| RS745320775 |
LCAT
|
Health Risk |
Likely pathogenic |
Norum disease, Norum disease |
| RS745321705 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS745322502 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS745323281 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745323298 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS745324562 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, JAG1-related disorder |
| RS745324944 |
FANCI
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group I, Fanconi anemia complementation group I |
| RS745325616 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Asphyxiating thoracic dystrophy 3, Jeune thoracic dystrophy |
| RS745325916 |
POLR1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Treacher Collins syndrome 3, Treacher Collins syndrome 3 |
| RS745325958 |
FGFR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Craniosynostosis syndrome, Trigonocephaly 1 |
| RS745327566 |
SLC12A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS745327620 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS745327804 |
RXYLT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745328476 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 26, Distal myopathy with posterior leg and anterior hand involvement |
| RS745328900 |
USH1G
|
Health Risk |
Pathogenic |
— |
| RS745329674 |
CLCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myotonia, autosomal recessive form |
| RS745331190 |
TMEM43
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 5, Cardiomyopathy |
| RS745332456 |
NDUFAF8
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial disease, Mitochondrial complex I deficiency |
| RS745333246 |
MYT1L
|
Health Risk |
Pathogenic/Likely pathogenic |
Neurodevelopmental disorder, Intellectual disability |
| RS745333409 |
DCDC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 66, Isolated neonatal sclerosing cholangitis |
| RS745333667 |
HGD
|
Health Risk |
Pathogenic/Likely pathogenic |
Alkaptonuria, Alkaptonuria |
| RS745334317 |
ADAR
|
Health Risk |
Pathogenic |
Aicardi-Goutieres syndrome 6, Symmetrical dyschromatosis of extremities |
| RS745334373 |
SLC12A1
|
Health Risk |
Pathogenic |
Bartter disease type 1, Bartter disease type 1 |
| RS745337023 |
ATP2A1
|
Health Risk |
Pathogenic |
Brody myopathy, Brody myopathy |
| RS745337140 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, Inborn genetic diseases |
| RS745337448 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Inborn genetic diseases |
| RS745337581 |
MAN1B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Rafiq syndrome, Rafiq syndrome |
| RS745337805 |
ALMS1
|
Health Risk |
Likely pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS745338204 |
HSPG2
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS745338278 |
CCDC88C
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745338284 |
TRMU
|
Health Risk |
Pathogenic/Likely pathogenic |
Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins, Aminoglycoside-induced deafness |
| RS745339673 |
EIF2AK4
|
Health Risk |
Pathogenic |
Familial pulmonary capillary hemangiomatosis, Familial pulmonary capillary hemangiomatosis |
| RS745340459 |
IQCB1
|
Health Risk |
Pathogenic |
Nephronophthisis, Senior-Loken syndrome 5 |
| RS745341246 |
TRPM1
|
Health Risk |
Likely pathogenic |
— |
| RS745341953 |
CERKL
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 26, Retinitis pigmentosa 26 |
| RS745342141 |
NUP107
|
Health Risk |
Pathogenic |
Galloway-Mowat syndrome 7, Galloway-Mowat syndrome 7 |
| RS745342273 |
NPHP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Nephronophthisis 3 |
| RS745342391 |
DEPDC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial focal epilepsy with variable foci, Inborn genetic diseases |
| RS745343484 |
POMGNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B3 |
| RS745343524 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS745343884 |
BTD
|
Health Risk |
Likely pathogenic |
Biotinidase deficiency, Biotinidase deficiency |
| RS745344342 |
DSPP
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745345009 |
GYG1
|
Health Risk |
Pathogenic |
Glycogen storage disease XV, Polyglucosan body myopathy type 2 |
| RS745346171 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS745348188 |
POLRMT
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation deficiency 55, Combined oxidative phosphorylation deficiency 55 |
| RS745348393 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS745348555 |
CRB1
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 1, Leber congenital amaurosis 8 |
| RS745349011 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745349258 |
ABCC8
|
Health Risk |
Pathogenic/Likely pathogenic |
Type 2 diabetes mellitus, Hyperinsulinemic hypoglycemia |
| RS745349945 |
RTEL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal recessive 5 |
| RS745350407 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS745351097 |
NUBPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745352764 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
FG syndrome, FG syndrome |
| RS74535389 |
ADCY1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 44, Inborn genetic diseases |
| RS745354512 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS74535574 |
APC
|
Health Risk |
Pathogenic |
Familial adenomatous polyposis 1, Neoplasm |
| RS745355767 |
NBN
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly, normal intelligence and immunodeficiency |
| RS745356934 |
NOG
|
Health Risk |
Pathogenic |
Symphalangism-brachydactyly syndrome, Symphalangism-brachydactyly syndrome |
| RS745357523 |
GCDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Glutaric aciduria, type 1 |
| RS745358717 |
CYP21A2
|
Health Risk |
Conflicting classifications of pathogenicity |
CYP21A2-related disorder, ADRENAL HYPERPLASIA |
| RS745358946 |
LYST
|
Health Risk |
Likely pathogenic |
Chédiak-Higashi syndrome, Chédiak-Higashi syndrome |
| RS745359242 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS745360675 |
GCDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Glutaric aciduria, type 1 |
| RS745361070 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS745361721 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS745363589 |
LAMA2
|
Health Risk |
Pathogenic |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS745363984 |
UBE3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Angelman syndrome, Inborn genetic diseases |
| RS745364489 |
BCHE
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of butyrylcholinesterase, BCHE-related disorder |
| RS745365163 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS745365232 |
CTNS
|
Health Risk |
Pathogenic |
Nephropathic cystinosis, Cystinosis |
| RS745366046 |
ALOX12B
|
Health Risk |
Pathogenic |
Autosomal recessive congenital ichthyosis 2, Autosomal recessive congenital ichthyosis 2 |
| RS745366278 |
FANCL
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group L |
| RS745366624 |
MMACHC
|
Health Risk |
Pathogenic/Likely pathogenic |
Cobalamin C disease, Cobalamin C disease |
| RS745366999 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Papillary renal cell carcinoma type 1 |
| RS745367639 |
MCCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylcrotonyl-CoA carboxylase 2 deficiency, 3-methylcrotonyl-CoA carboxylase 2 deficiency |
| RS745368359 |
CYP4F22
|
Health Risk |
Pathogenic |
Autosomal recessive congenital ichthyosis 5, Lamellar ichthyosis |