NRIP1 Chromosome 21
Nuclear receptor interacting protein 1
Upload your DNA to see your personal genotypes for variants in NRIP1.
What This Gene Does
Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor. [provided by RefSeq, Jul 2008]
Associated Conditions (4)
Inborn genetic diseases
NRIP1-related disorder
Congenital anomaly of kidney and urinary tract
Congenital anomalies of kidney and urinary tract 3
Key Variants
RS140653587
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS140803495
Conflicting classifications of pathogenicity
NRIP1-related disorder, NRIP1-related disorder
Health Risk
RS143089816
Conflicting classifications of pathogenicity
Inborn genetic diseases, NRIP1-related disorder, Inborn genetic diseases
Health Risk
RS143638809
Conflicting classifications of pathogenicity
Inborn genetic diseases, NRIP1-related disorder, Inborn genetic diseases
Health Risk
RS147293713
Conflicting classifications of pathogenicity
NRIP1-related disorder, NRIP1-related disorder
Health Risk
RS34937272
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS371021775
Conflicting classifications of pathogenicity
NRIP1-related disorder, NRIP1-related disorder
Health Risk
RS74503862
Conflicting classifications of pathogenicity
Inborn genetic diseases, NRIP1-related disorder, Inborn genetic diseases
Health Risk
RS745308120
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS1555879360
Pathogenic
Congenital anomaly of kidney and urinary tract, Congenital anomalies of kidney and urinary tract 3, Congenital anomaly of kidney and urinary tract
Health Risk
All Variants (10)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS140653587 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS140803495 | Health Risk | Conflicting classifications of pathogenicity | NRIP1-related disorder, NRIP1-related disorder |
| RS143089816 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, NRIP1-related disorder, Inborn genetic diseases |
| RS143638809 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, NRIP1-related disorder, Inborn genetic diseases |
| RS147293713 | Health Risk | Conflicting classifications of pathogenicity | NRIP1-related disorder, NRIP1-related disorder |
| RS34937272 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS371021775 | Health Risk | Conflicting classifications of pathogenicity | NRIP1-related disorder, NRIP1-related disorder |
| RS74503862 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, NRIP1-related disorder, Inborn genetic diseases |
| RS745308120 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS1555879360 | Health Risk | Pathogenic | Congenital anomaly of kidney and urinary tract, Congenital anomalies of kidney and urinary tract 3, Congenital anomaly of kidney and urinary tract |