| RS557456591 |
CACNA1E
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS557461059 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS557462297 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 5, Charcot-Marie-Tooth disease dominant intermediate E |
| RS557463209 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS55748088 |
ITGB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Junctional epidermolysis bullosa with pyloric atresia |
| RS557483957 |
COMP
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudoachondroplastic spondyloepiphyseal dysplasia syndrome, Multiple epiphyseal dysplasia type 1 |
| RS55751949 |
PHKG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease IXc, PHKG2-related disorder |
| RS557521971 |
BUB1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Mosaic variegated aneuploidy syndrome 1, Ovarian cancer |
| RS557526069 |
TTN
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS55752621 |
EHHADH
|
Health Risk |
Conflicting classifications of pathogenicity |
Chronic kidney disease, Chronic kidney disease |
| RS557527090 |
ARSA
|
Health Risk |
Pathogenic |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS55752843 |
POLRMT
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation deficiency 55, Combined oxidative phosphorylation deficiency 55 |
| RS557529420 |
ABCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tangier disease, Hypoalphalipoproteinemia |
| RS557533784 |
MTOR
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS557535632 |
BAG3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 6, Dilated cardiomyopathy 1HH |
| RS557539356 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2Q, Epidermolysis bullosa simplex 5B |
| RS557540994 |
SKIC3
|
Health Risk |
Conflicting classifications of pathogenicity |
SKIC3-related disorder, SKIC3-related disorder |
| RS557545474 |
LYST
|
Health Risk |
Conflicting classifications of pathogenicity |
Chédiak-Higashi syndrome, Autoinflammatory syndrome |
| RS55755457 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS557559653 |
TMEM216
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 2, Meckel syndrome |
| RS557559740 |
SCN8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cognitive impairment with or without cerebellar ataxia, Seizures |
| RS55756709 |
PNKP
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly, seizures |
| RS557577836 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS557578629 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS557581298 |
SLC16A1
|
Health Risk |
Pathogenic |
SLC16A1-related disorder, SLC16A1-related disorder |
| RS557590325 |
CD46
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS557592503 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Medulloblastoma |
| RS557596726 |
POR
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency, Congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency |
| RS55759912 |
TEX14
|
Health Risk |
Conflicting classifications of pathogenicity |
Spermatogenic failure 23, Spermatogenic failure 23 |
| RS55760494 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS55760835 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS557609728 |
RBP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS557611780 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
CREBBP-related disorder, Rubinstein-Taybi syndrome |
| RS55761944 |
ERCC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cockayne syndrome, Fanconi anemia complementation group Q |
| RS557620034 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1D, Autosomal recessive nonsyndromic hearing loss 84A |
| RS557621248 |
FAM186B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS557622245 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS55762754 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS557627895 |
CACNA1B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS557636016 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, ZNF469-related disorder |
| RS55763607 |
BRCA2
|
Health Risk |
Pathogenic |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS557640338 |
NBEAL2
|
Health Risk |
Conflicting classifications of pathogenicity |
NBEAL2-related disorder, NBEAL2-related disorder |
| RS557643577 |
PARD3
|
Health Risk |
risk factor |
Neural tube defect, Neural tube defect |
| RS55765051 |
KIF7
|
Health Risk |
Conflicting classifications of pathogenicity |
Acrocallosal syndrome, Hydrolethalus syndrome 2 |
| RS557659943 |
UMOD
|
Health Risk |
Conflicting classifications of pathogenicity |
Kidney disorder, Familial juvenile hyperuricemic nephropathy type 1 |
| RS557669708 |
SLC3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystinuria, Cystinuria |
| RS557670363 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 6 |
| RS557671408 |
MYOM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiovascular phenotype |
| RS55767801 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS55767910 |
TAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class I deficiency, TAP1-related disorder |
| RS557681960 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, arthrochalasia type |
| RS557685746 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Elliptocytosis 2, Hereditary spherocytosis type 3 |
| RS557687418 |
ADCY5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS557688789 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS557690276 |
MCPH1
|
Health Risk |
Likely pathogenic |
MCPH1-related disorder, MCPH1-related disorder |
| RS557699482 |
FKTN
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A |
| RS55770810 |
BRCA1
|
Health Risk |
Pathogenic |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS557709223 |
ALS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 2, juvenile |
| RS557710295 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS55771538 |
CYP1B1
|
Health Risk |
Likely pathogenic |
Glaucoma 3A, CYP1B1-related glaucoma with or without anterior segment dysgenesis |
| RS557732922 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS557734046 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS55773834 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS557739576 |
BBS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 1, Bardet-Biedl syndrome |
| RS557741620 |
DCAF17
|
Health Risk |
Conflicting classifications of pathogenicity |
Woodhouse-Sakati syndrome, DCAF17-related disorder |
| RS557741807 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate E, Focal segmental glomerulosclerosis 5 |
| RS557742097 |
NSUN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS557746506 |
TMEM94
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual developmental disorder with cardiac defects and dysmorphic facies, Intellectual developmental disorder with cardiac defects and dysmorphic facies |
| RS557754125 |
FGFR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pfeiffer syndrome, Hypogonadotropic hypogonadism 2 with or without anosmia |
| RS55775473 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary breast ovarian cancer syndrome |
| RS557760409 |
LAMA5
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA5-related disorder, Inborn genetic diseases |
| RS557762861 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
HSPG2-related disorder, HSPG2-related disorder |
| RS557771609 |
CFAP53
|
Health Risk |
Likely pathogenic |
Heterotaxy, Heterotaxy |
| RS557772454 |
SLC12A3
|
Health Risk |
Likely pathogenic |
— |
| RS557773336 |
CRX
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 2, Leber congenital amaurosis 7 |
| RS55777503 |
PRKN
|
Health Risk |
Pathogenic |
Young-onset Parkinson disease, Autosomal recessive juvenile Parkinson disease 2 |
| RS557777623 |
UNC80
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypotonia, infantile |
| RS557789686 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS557790186 |
ALG6
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG6-congenital disorder of glycosylation 1C, Malignant tumor of esophagus |
| RS557796016 |
MSH4
|
Health Risk |
Likely pathogenic |
Genetic non-acquired premature ovarian failure, Genetic non-acquired premature ovarian failure |
| RS55779802 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
POLG-related disorder, Progressive sclerosing poliodystrophy |
| RS557803591 |
KCNN4
|
Health Risk |
Conflicting classifications of pathogenicity |
KCNN4-related disorder, Inborn genetic diseases |
| RS557807920 |
IFT43
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS557813179 |
ESCO2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Roberts-SC phocomelia syndrome |
| RS55782189 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS557822238 |
DNAAF19
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 17, Primary ciliary dyskinesia |
| RS557830930 |
EVC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS557834060 |
EPHB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS557835636 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS557836108 |
ITGB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Epidermolysis bullosa |
| RS557838138 |
PTPN23
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS557849165 |
MYH3
|
Health Risk |
Pathogenic/Likely pathogenic |
Spondylocarpotarsal synostosis syndrome, Contractures |
| RS557853306 |
MTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylcobalamin deficiency type cblG, Inborn genetic diseases |
| RS55785527 |
TNFRSF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
TNF receptor-associated periodic fever syndrome (TRAPS), TNF receptor-associated periodic fever syndrome (TRAPS) |
| RS557865832 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS557867164 |
NUS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital disorder of glycosylation, type IAA |
| RS557868420 |
KCNH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Inborn genetic diseases |
| RS557870969 |
NEB
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS557873884 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, MYLK-related disorder |
| RS557875547 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |