| RS556510460 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Birt-Hogg-Dube syndrome |
| RS556513891 |
RNF213
|
Health Risk |
Pathogenic |
Moyamoya disease 2, Moyamoya disease 2 |
| RS556517027 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 5C, with pyloric atresia |
| RS556518689 |
ADGRG1
|
Health Risk |
Likely pathogenic |
Bilateral frontoparietal polymicrogyria, Bilateral frontoparietal polymicrogyria |
| RS556524594 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS556530627 |
CSF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse leukoencephalopathy with spheroids, CSF1R-related disorder |
| RS55653533 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS556536964 |
MYH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 14 |
| RS556542553 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS556546220 |
JPH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiovascular phenotype |
| RS556547267 |
DNAI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 9 |
| RS556548077 |
MYH14
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 4A, Peripheral neuropathy-myopathy-hoarseness-hearing loss syndrome |
| RS556550485 |
EYA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1J |
| RS55655121 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS55655222 |
ICOS
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS556552435 |
TPO
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of iodide peroxidase, Deficiency of iodide peroxidase |
| RS556553243 |
POGZ
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual disability-microcephaly-strabismus-behavioral abnormalities syndrome |
| RS556553563 |
TFR2
|
Health Risk |
Likely pathogenic |
Hemochromatosis type 3, Hemochromatosis type 3 |
| RS556556052 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, childhood absence |
| RS556559035 |
GPIHBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS556562410 |
BSCL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Monogenic diabetes |
| RS55656324 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS556563706 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 9 |
| RS556576971 |
NEIL1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS556579725 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Inborn genetic diseases |
| RS556581174 |
GCK
|
Health Risk |
Pathogenic |
Monogenic diabetes, Maturity-onset diabetes of the young type 2 |
| RS556585167 |
WHRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2D, Autosomal recessive nonsyndromic hearing loss 31 |
| RS55658999 |
AURKC
|
Health Risk |
Pathogenic |
Infertility associated with multi-tailed spermatozoa and excessive DNA, Male infertility with spermatogenesis disorder |
| RS556598169 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS55660516 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 4 |
| RS55660660 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS556618384 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease, adult type |
| RS55662069 |
MYO6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 22, Autosomal recessive nonsyndromic hearing loss 37 |
| RS556624010 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS55663050 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS556640912 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS556646437 |
CNTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, familial adult myoclonic |
| RS556651007 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lip and oral cavity carcinoma |
| RS55665437 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCA4-related disorder, ABCA4-related disorder |
| RS556654678 |
UNC13D
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis 3 |
| RS556661896 |
MFSD8
|
Health Risk |
Likely pathogenic |
Neuronal ceroid lipofuscinosis 7, Neuronal ceroid lipofuscinosis 7 |
| RS55666220 |
IFNGR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 27A, Disseminated atypical mycobacterial infection |
| RS556669370 |
KMT2D
|
Health Risk |
Pathogenic |
Kabuki syndrome 1, Kabuki syndrome 1 |
| RS55667299 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS556673375 |
HIVEP2
|
Health Risk |
Pathogenic |
— |
| RS556677734 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS556681288 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease, adult type |
| RS556687525 |
PLEKHG5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS556687934 |
TCF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Pitt-Hopkins syndrome, Pitt-Hopkins syndrome |
| RS556689644 |
MEGF8
|
Health Risk |
Conflicting classifications of pathogenicity |
MEGF8-related Carpenter syndrome, Inborn genetic diseases |
| RS556692354 |
PDE6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS556692411 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS55669553 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Primary dilated cardiomyopathy |
| RS556704888 |
CLCNKA
|
Health Risk |
Conflicting classifications of pathogenicity |
Bartter disease type 4B, CHARGE syndrome |
| RS556707582 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial meningioma, Hereditary cancer-predisposing syndrome |
| RS55671452 |
DDHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 28, Hereditary spastic paraplegia 28 |
| RS556715100 |
SPAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 28 |
| RS556720151 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS55672414 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 7 |
| RS556734208 |
KLK4
|
Health Risk |
Pathogenic |
Amelogenesis imperfecta type 2A1, Amelogenesis imperfecta type 2A1 |
| RS556734672 |
MAX
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS556741970 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS556744419 |
CERKL
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS556745324 |
CYP27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cholestanol storage disease, Cholestanol storage disease |
| RS556745550 |
SRCAP
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS55674815 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS556748657 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group A |
| RS556749534 |
RYR1
|
Health Risk |
Likely pathogenic |
RYR1-related myopathy, RYR1-related myopathy |
| RS556751671 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS556752387 |
MYO18B
|
Health Risk |
Pathogenic/Likely pathogenic |
Klippel-Feil anomaly-myopathy-facial dysmorphism syndrome, Klippel-Feil anomaly-myopathy-facial dysmorphism syndrome |
| RS556759055 |
REN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Renal tubular dysgenesis of genetic origin |
| RS55676195 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Early-onset myopathy with fatal cardiomyopathy |
| RS55676763 |
CLCN5
|
Health Risk |
Conflicting classifications of pathogenicity |
Dent disease type 1, Inborn genetic diseases |
| RS556778314 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS556778889 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS556779970 |
PIEZO2
|
Health Risk |
Pathogenic |
Arthrogryposis, distal |
| RS556780206 |
SLC39A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary acrodermatitis enteropathica, Hereditary acrodermatitis enteropathica |
| RS55678259 |
CYP4V2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bietti crystalline corneoretinal dystrophy, Bietti crystalline corneoretinal dystrophy |
| RS556783606 |
RSPH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 32, Inborn genetic diseases |
| RS55678461 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS556784868 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS556788032 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS556788423 |
FLVCR1
|
Health Risk |
Pathogenic/Likely pathogenic |
Posterior column ataxia-retinitis pigmentosa syndrome, Retinal dystrophy |
| RS556791789 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS556794126 |
CYP17A1
|
Health Risk |
Pathogenic/Likely pathogenic |
17-alpha-hydroxylase/17, 20-lyase deficiency |
| RS55680026 |
NPC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type C1 |
| RS556803400 |
MCPH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 1, primary |
| RS556804456 |
WT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Drash syndrome, Frasier syndrome |
| RS556805686 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS556806561 |
RFX5
|
Health Risk |
Pathogenic |
MHC class II deficiency 3, MHC class II deficiency 3 |
| RS556807466 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS556808514 |
MICALL2
|
Health Risk |
Pathogenic |
Joubert syndrome 1, Joubert syndrome 1 |
| RS55681376 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Idiopathic hypereosinophilic syndrome |
| RS556819076 |
SLCO2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, SLCO2A1-related disorder |
| RS556820261 |
TRIM63
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS556827873 |
GDAP1
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease type 4A, Charcot-Marie-Tooth disease type 4A |
| RS55682875 |
GRHL2
|
Health Risk |
Conflicting classifications of pathogenicity |
GRHL2-related disorder, GRHL2-related disorder |
| RS556829801 |
GAMT
|
Health Risk |
Pathogenic/Likely pathogenic |
Cerebral creatine deficiency syndrome, Deficiency of guanidinoacetate methyltransferase |
| RS55683010 |
SOX2
|
Health Risk |
Pathogenic |
Anophthalmia/microphthalmia-esophageal atresia syndrome, Anophthalmia/microphthalmia-esophageal atresia syndrome |
| RS556830991 |
RAD50
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |