| RS556834250 |
DOK7
|
Health Risk |
Pathogenic |
Congenital myasthenic syndrome 10, Fetal akinesia deformation sequence 1 |
| RS556840308 |
NTRK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary insensitivity to pain with anhidrosis, Inborn genetic diseases |
| RS556849969 |
ASPM
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 5, primary |
| RS55685423 |
CHRNB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy 3, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS556862476 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS556868058 |
TRRAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, TRRAP-related disorder |
| RS556869079 |
WDR19
|
Health Risk |
Pathogenic |
Asphyxiating thoracic dystrophy 5, Senior-Loken syndrome 8 |
| RS556872918 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS556875684 |
MFSD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 7, Inborn genetic diseases |
| RS55687573 |
FANCC
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group C, Fanconi anemia complementation group C |
| RS55687637 |
VWF
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary von Willebrand disease, von Willebrand disease type 1 |
| RS556881504 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS556882699 |
USH2A
|
Health Risk |
Pathogenic |
— |
| RS556886570 |
JPH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy |
| RS556887600 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS55688805 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, MYO15A-related disorder |
| RS55688870 |
RUFY4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS55689095 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant tumor of breast, Breast-ovarian cancer |
| RS556892787 |
SARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperuricemia, pulmonary hypertension |
| RS55689343 |
FGFR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Craniosynostosis syndrome, Saethre-Chotzen syndrome |
| RS556893466 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS556893517 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS556897484 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS556901417 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Holoprosencephaly 7 |
| RS556910528 |
EVC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS556913973 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS556914502 |
CUL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism type 2E, Pseudohypoaldosteronism type 2E |
| RS556916354 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Cardiovascular phenotype |
| RS556917839 |
DNAJC21
|
Health Risk |
Pathogenic |
Bone marrow failure syndrome 3, Bone marrow failure syndrome 3 |
| RS556925652 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, Sensory ataxic neuropathy |
| RS556930902 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS556931606 |
RAB23
|
Health Risk |
Conflicting classifications of pathogenicity |
Carpenter syndrome, RAB23-related Carpenter syndrome |
| RS556931817 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS55693364 |
SLC2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
GLUT1 deficiency syndrome 1, autosomal recessive |
| RS556936569 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS55693709 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS556940270 |
NBAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS556943368 |
ITPR1
|
Health Risk |
Likely pathogenic |
— |
| RS556945561 |
PHKG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease IXc, Glycogen storage disease IXc |
| RS556948427 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Tibial muscular dystrophy |
| RS55695051 |
STRADA
|
Health Risk |
Pathogenic |
Self-limited epilepsy with centrotemporal spikes, Self-limited epilepsy with centrotemporal spikes |
| RS556958354 |
WRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Werner syndrome, Wiskott-Aldrich syndrome |
| RS556959034 |
MARVELD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 49, Autosomal recessive nonsyndromic hearing loss 49 |
| RS556959164 |
SLC25A22
|
Health Risk |
Conflicting classifications of pathogenicity |
Early myoclonic encephalopathy, Early-infantile DEE |
| RS55696153 |
TTN
|
Health Risk |
Likely pathogenic |
Early-onset myopathy with fatal cardiomyopathy, Cardiovascular phenotype |
| RS556967635 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS55697431 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS556977377 |
CHD8
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with autism and macrocephaly, Intellectual developmental disorder with autism and macrocephaly |
| RS556977618 |
MMACHC
|
Health Risk |
Pathogenic/Likely pathogenic |
Cobalamin C disease, Cobalamin C disease |
| RS55698015 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
ERCC6-related disorder, ERCC6-related disorder |
| RS556991020 |
TBX18
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS556993869 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS556999563 |
DNAJB6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant limb-girdle muscular dystrophy type 1D (DNAJB6), Autosomal dominant limb-girdle muscular dystrophy type 1D (DNAJB6) |
| RS557004700 |
MERTK
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS557012154 |
ATM
|
Health Risk |
Pathogenic |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS557015233 |
LPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperlipoproteinemia, type I |
| RS557017447 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 42 |
| RS557019144 |
ADAMTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS557020239 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS557021652 |
FANCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group E, Fanconi anemia complementation group E |
| RS557023458 |
C6
|
Health Risk |
Pathogenic/Likely pathogenic |
Complement component 6 deficiency, C6-related disorder |
| RS55702495 |
CHAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial infantile myasthenia, Familial infantile myasthenia |
| RS557025834 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, KBG syndrome |
| RS557038070 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 9, Meckel syndrome |
| RS55704151 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS557041940 |
OPA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Optic atrophy 3, 3-Methylglutaconic aciduria type 3 |
| RS557043245 |
P2RY12
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS557044760 |
BSCL2
|
Health Risk |
Pathogenic |
Congenital generalized lipodystrophy type 2, Congenital generalized lipodystrophy type 2 |
| RS557047531 |
RAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency, autosomal recessive |
| RS55704830 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myopathy |
| RS557048986 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Cataract 41 |
| RS557049479 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS557049566 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spondylometaphyseal dysplasia - Sutcliffe type, Glomerulopathy with fibronectin deposits 2 |
| RS557052809 |
ATP1A3
|
Health Risk |
Pathogenic |
Dystonia 12, Dystonia 12 |
| RS557057587 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS55705857 |
CCDC26
|
Health Risk |
risk factor |
Glioma susceptibility 7, Glioma susceptibility 7 |
| RS557058818 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS557063759 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS55706546 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glomerulopathy with fibronectin deposits 2, Glomerulopathy with fibronectin deposits 2 |
| RS557085910 |
MATR3
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 21, Amyotrophic lateral sclerosis type 21 |
| RS55708915 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS557096550 |
FKTN
|
Health Risk |
Pathogenic |
Dilated cardiomyopathy 1X, Dilated cardiomyopathy 1X |
| RS557097410 |
DHCR7
|
Health Risk |
Pathogenic |
Smith-Lemli-Opitz syndrome, Inborn genetic diseases |
| RS557105262 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1G |
| RS557106858 |
NDUFA10
|
Health Risk |
Conflicting classifications of pathogenicity |
Leigh syndrome, Mitochondrial complex I deficiency |
| RS557113034 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS55711326 |
FOXP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Insulin-dependent diabetes mellitus secretory diarrhea syndrome, Insulin-dependent diabetes mellitus secretory diarrhea syndrome |
| RS557113294 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS557118570 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS557119336 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS557120711 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS55712212 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS557125278 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS557125328 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS55712755 |
UPF3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndromic X-linked intellectual disability 14, Syndromic X-linked intellectual disability 14 |
| RS557128093 |
ECHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial short-chain Enoyl-Coa hydratase 1 deficiency, Mitochondrial short-chain Enoyl-Coa hydratase 1 deficiency |
| RS557128345 |
WDR72
|
Health Risk |
Pathogenic |
Amelogenesis imperfecta hypomaturation type 2A3, Renal tubular acidosis |
| RS55713856 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS557147929 |
NIPBL
|
Health Risk |
Conflicting classifications of pathogenicity |
Cornelia de Lange syndrome 1, Cornelia de Lange syndrome 1 |
| RS557150117 |
GOT2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |