| RS557878787 |
JPH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiovascular phenotype |
| RS557878856 |
AMPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscle AMP deaminase deficiency, Muscle AMP deaminase deficiency |
| RS557880129 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS557884699 |
MMAB
|
Health Risk |
Pathogenic/Likely pathogenic |
Methylmalonic aciduria, cblB type |
| RS557890655 |
ABCG8
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Sitosterolemia 1 |
| RS557891718 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial melanoma |
| RS557896607 |
MKS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS557898007 |
KLHL40
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 8, Nemaline myopathy 8 |
| RS557906137 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS55791823 |
EIF2AK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolcott-Rallison dysplasia, Monogenic diabetes |
| RS557920637 |
RP1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
Occult macular dystrophy, Inborn genetic diseases |
| RS55792975 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS557930357 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism type 2C, Neuropathy |
| RS557932393 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Polycystic kidney disease |
| RS557937095 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS557939030 |
ASTN2;TRIM32
|
Health Risk |
Conflicting classifications of pathogenicity |
Sarcotubular myopathy, Bardet-Biedl syndrome 11 |
| RS557939077 |
ATP1A3
|
Health Risk |
Pathogenic |
Cerebellar ataxia-areflexia-pes cavus-optic atrophy-sensorineural hearing loss syndrome, Cerebellar ataxia-areflexia-pes cavus-optic atrophy-sensorineural hearing loss syndrome |
| RS55794205 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS557950249 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS557951372 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS557957962 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS55795842 |
NCF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Granulomatous disease, chronic |
| RS557960320 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Cardiovascular phenotype |
| RS557962090 |
TCTN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Orofacial-digital syndrome IV, Joubert syndrome 18 |
| RS55796504 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS557966264 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS557967677 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss, Autosomal dominant nonsyndromic hearing loss 17 |
| RS55797424 |
CACNA1D
|
Health Risk |
Conflicting classifications of pathogenicity |
Acute myeloid leukemia, Acute myeloid leukemia |
| RS557976330 |
COL4A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, COL4A2-related disorder |
| RS557979163 |
DNAH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spermatogenic failure 18, Ciliary dyskinesia |
| RS55798001 |
BIVM-ERCC5;ERCC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group G |
| RS557980103 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS557983485 |
TRAF3IP2
|
Health Risk |
Pathogenic |
Candidiasis, familial |
| RS557983754 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS55798804 |
RIPK4
|
Health Risk |
Conflicting classifications of pathogenicity |
Bartsocas-Papas syndrome 1, RIPK4-related disorder |
| RS557989446 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS55799208 |
CXCR2
|
Health Risk |
Conflicting classifications of pathogenicity |
CXCR2-related disorder, CXCR2-related disorder |
| RS557994288 |
MMACHC
|
Health Risk |
Conflicting classifications of pathogenicity |
Disorders of Intracellular Cobalamin Metabolism, Cobalamin C disease |
| RS557996561 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS558000439 |
KAT6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS55800493 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS558005496 |
ETFDH
|
Health Risk |
Pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS55801750 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS558019875 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS558031489 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 5C, with pyloric atresia |
| RS558035857 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Brittle cornea syndrome 1, Cardiovascular phenotype |
| RS558036408 |
ADAMTS17
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani 4 syndrome, recessive |
| RS558037268 |
ATP7B
|
Health Risk |
Likely pathogenic |
Wilson disease, ATP7B-related disorder |
| RS558040549 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Peutz-Jeghers syndrome |
| RS558042478 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Epilepsy |
| RS558048038 |
CFHR2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS558051943 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, Rubinstein-Taybi syndrome |
| RS558052679 |
POMGNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2O, Congenital Muscular Dystrophy |
| RS558054655 |
WRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Werner syndrome, Inborn genetic diseases |
| RS558064127 |
CRPPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital Muscular Dystrophy, alpha-dystroglycan related |
| RS558069434 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS55807335 |
SPTBN5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS558077210 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS55808233 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS558084375 |
ISCU
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary myopathy with lactic acidosis due to ISCU deficiency, ISCU-related disorder |
| RS558106649 |
KCNC3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS55810667 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS558108271 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Brittle cornea syndrome 1 |
| RS558109660 |
UGT1A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Crigler-Najjar syndrome, type II |
| RS55812333 |
UNG
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyper-IgM syndrome type 5, UNG-related disorder |
| RS558123422 |
NR2E3
|
Health Risk |
Conflicting classifications of pathogenicity |
Enhanced S-cone syndrome, Retinitis pigmentosa 37 |
| RS558125416 |
LONP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS558135361 |
RNU4ATAC
|
Health Risk |
Pathogenic/Likely pathogenic |
RNU4ATAC spectrum disorder, RNU4ATAC spectrum disorder |
| RS558139194 |
CUBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Imerslund-Grasbeck syndrome, Proteinuria |
| RS558148933 |
IFT172
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 71, Short-rib thoracic dysplasia 10 with or without polydactyly |
| RS558155146 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS55816283 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Alport syndrome, Kidney disorder |
| RS558163499 |
PXDN
|
Health Risk |
Pathogenic |
Anterior segment dysgenesis 7, Anterior segment dysgenesis 7 |
| RS55816687 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS55816927 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS558173513 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Osteogenesis imperfecta |
| RS558173961 |
MUTYH
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS55817813 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS558180061 |
FGFR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteoglophonic dysplasia, Craniosynostosis syndrome |
| RS558186319 |
MAGEL2
|
Health Risk |
Conflicting classifications of pathogenicity |
MAGEL2-related disorder, MAGEL2-related disorder |
| RS558187116 |
FKTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Walker-Warburg congenital muscular dystrophy, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS558191127 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS558191826 |
OBSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
3M syndrome 2, 3M syndrome 2 |
| RS558195536 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss, Autosomal dominant nonsyndromic hearing loss 17 |
| RS55819880 |
SERPINA1
|
Health Risk |
Pathogenic; other |
PI S(IIYAMA), Alpha-1-antitrypsin deficiency |
| RS558200846 |
ADCY5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS558205050 |
CSF2RB
|
Health Risk |
Conflicting classifications of pathogenicity |
Surfactant metabolism dysfunction, pulmonary |
| RS558208878 |
KCNK4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS55821172 |
TRIOBP
|
Health Risk |
Conflicting classifications of pathogenicity |
TRIOBP-related disorder, TRIOBP-related disorder |
| RS55821557 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS55821615 |
SPEG
|
Health Risk |
Conflicting classifications of pathogenicity |
SPEG-related disorder, SPEG-related disorder |
| RS55821741 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS558224639 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 5C, with pyloric atresia |
| RS558239439 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS55824172 |
TBK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Motor neuron disease, Frontotemporal dementia and/or amyotrophic lateral sclerosis 4 |
| RS55824746 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS558249175 |
SNRPB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS55824996 |
LAMB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS558250151 |
ERCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, Xeroderma pigmentosum |
| RS558254502 |
BCKDHA
|
Health Risk |
Likely pathogenic |
Maple syrup urine disease, Malignant tumor of esophagus |