| RS558259191 |
MUSK
|
Health Risk |
Conflicting classifications of pathogenicity |
Fetal akinesia deformation sequence 1, Congenital myasthenic syndrome 9 |
| RS558259739 |
CBS
|
Health Risk |
Conflicting classifications of pathogenicity |
HYPERHOMOCYSTEINEMIA, THROMBOTIC |
| RS55826142 |
MUSK
|
Health Risk |
Conflicting classifications of pathogenicity |
Fetal akinesia deformation sequence 1, Congenital myasthenic syndrome 9 |
| RS558265763 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Stickler syndrome type 2, Marshall syndrome |
| RS558267822 |
PYGM
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type V |
| RS558269137 |
FLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Ichthyosis vulgaris, Dermatitis |
| RS558274487 |
MFSD8
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis 7, Neuronal ceroid lipofuscinosis 7 |
| RS558276175 |
MAPK12
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS558281905 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS558282228 |
CNTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, familial adult myoclonic |
| RS558285072 |
ZFYVE26
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 15, Spastic paraplegia |
| RS558287069 |
VPS13A
|
Health Risk |
Conflicting classifications of pathogenicity |
Chorea-acanthocytosis, Inborn genetic diseases |
| RS55828982 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS558291025 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS558291810 |
KBTBD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 6, Inborn genetic diseases |
| RS558295858 |
KCNV2
|
Health Risk |
Conflicting classifications of pathogenicity |
KCNV2-related disorder, KCNV2-related disorder |
| RS558302979 |
RAD50
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS558304720 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS55830572 |
PDGFRB
|
Health Risk |
Conflicting classifications of pathogenicity |
Basal ganglia calcification, idiopathic |
| RS558306648 |
DNM1L
|
Health Risk |
Conflicting classifications of pathogenicity |
DNM1L-related disorder, DNM1L-related disorder |
| RS55830714 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS558308794 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS55830907 |
PRKN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive juvenile Parkinson disease 2, PRKN-related disorder |
| RS55831697 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS558318269 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Hereditary cancer-predisposing syndrome |
| RS55832242 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS558323413 |
CIROZ
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS55832599 |
TP53
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Li-Fraumeni syndrome |
| RS55833327 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS558336915 |
PLOD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bruck syndrome 2, Osteogenesis imperfecta |
| RS55833708 |
TTBK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 11, Inborn genetic diseases |
| RS558341655 |
PIGN
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Multiple congenital anomalies-hypotonia-seizures syndrome 1 |
| RS558345043 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS558345996 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS558347312 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS55834942 |
HNF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 3, Insulin-resistant diabetes mellitus |
| RS55835607 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS558365010 |
GRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 3, Fraser syndrome 3 |
| RS558365108 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS558365811 |
NBAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Short stature-optic atrophy-Pelger-Huët anomaly syndrome, Short stature-optic atrophy-Pelger-Huët anomaly syndrome |
| RS55836779 |
BLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 11, Maturity-onset diabetes of the young type 11 |
| RS558369303 |
MEGF10
|
Health Risk |
Conflicting classifications of pathogenicity |
MEGF10-related myopathy, MEGF10-related disorder |
| RS55837610 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Early-onset myopathy with fatal cardiomyopathy |
| RS558379347 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS558383133 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS55838839 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Early-onset myopathy with fatal cardiomyopathy |
| RS558397748 |
HIBCH
|
Health Risk |
Pathogenic/Likely pathogenic |
3-hydroxyisobutyryl-CoA hydrolase deficiency, 3-hydroxyisobutyryl-CoA hydrolase deficiency |
| RS55840049 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease, adult type |
| RS558403928 |
DNAAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS558409444 |
PLCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome, type 3 |
| RS558416040 |
PHOX2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital central hypoventilation, Neuroblastoma |
| RS558416191 |
ABCB4
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCB4-related disorder, ABCB4-related disorder |
| RS558421445 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS558424479 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica inversa, autosomal recessive |
| RS55842557 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS55842922 |
CLRN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 3, Usher syndrome type 3 |
| RS55842957 |
BRCA1
|
Health Risk |
Likely pathogenic |
Breast-ovarian cancer, familial |
| RS558429618 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 4, Senior-Loken syndrome 4 |
| RS558436556 |
SZT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS558440722 |
FBN3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS558440936 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1DD |
| RS558451720 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Inborn genetic diseases |
| RS558452690 |
NPC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type C1 |
| RS558452873 |
KCNQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS558458433 |
RUNX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cleidocranial dysostosis, Cleidocranial dysostosis |
| RS558458890 |
MYO7A
|
Health Risk |
Likely pathogenic |
Usher syndrome type 1, Usher syndrome type 1 |
| RS558463276 |
FSIP2
|
Health Risk |
Pathogenic |
Spermatogenic failure 34, Spermatogenic failure 34 |
| RS55847238 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Cardiovascular phenotype |
| RS55847618 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS55847708 |
DDB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group E |
| RS558477960 |
BTD
|
Health Risk |
Conflicting classifications of pathogenicity |
Biotinidase deficiency, BTD-related disorder |
| RS55848034 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS558481390 |
PANK2
|
Health Risk |
Pathogenic |
Hypoprebetalipoproteinemia, acanthocytosis |
| RS55848325 |
BBS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 1 |
| RS558488257 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Weill-Marchesani syndrome |
| RS558489382 |
EPS8L2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS55849096 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Hematuria |
| RS558493952 |
CELA2A
|
Health Risk |
Likely pathogenic |
Coronary artery disorder, Hypertensive disorder |
| RS55849640 |
EFEMP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Doyne honeycomb retinal dystrophy, EFEMP1-related disorder |
| RS55849827 |
FANCL
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group L |
| RS55850344 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS55850759 |
STK4
|
Health Risk |
Conflicting classifications of pathogenicity |
STK4-related disorder, Combined immunodeficiency due to STK4 deficiency |
| RS558510095 |
LZTR1
|
Health Risk |
Pathogenic/Likely pathogenic |
LZTR1-related schwannomatosis, Cardiovascular phenotype |
| RS558514709 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS55851803 |
BRCA1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS55851925 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Inborn genetic diseases |
| RS558519810 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Inborn genetic diseases |
| RS558524280 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS55852466 |
TREX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 1, Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations |
| RS55852620 |
ABCB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tramadol response, Tramadol response |
| RS55853041 |
PSMB8
|
Health Risk |
Conflicting classifications of pathogenicity |
Proteasome-associated autoinflammatory syndrome 1, Autoinflammatory syndrome |
| RS55853138 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS55853199 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS55853245 |
SGCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Myoclonic dystonia 11, Myoclonic dystonia 11 |
| RS558543425 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS558548172 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Stickler syndrome type 2, Fibrochondrogenesis 1 |
| RS55854959 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS55855125 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy 1, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS558551880 |
CPLANE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 17, Orofaciodigital syndrome type 6 |
| RS558556902 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |