RUFY4 Chromosome 2

RUN and FYVE domain containing 4
1 variant 1 Health Risk

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What This Gene Does
Enables phosphatidylinositol-3-phosphate binding activity. Involved in autophagosome assembly; cellular response to interleukin-4; and positive regulation of macroautophagy. Located in autophagosome. [provided by Alliance of Genome Resources, Apr 2025]
Gene Info
Gene Group
Zinc fingers FYVE-type
Locus Type
gene with protein product
Location
2q35
Ensembl
ENSG00000188282
Key Variants
All Variants (1)
RSID Category Clinical Significance Conditions
RS55688870 Health Risk Conflicting classifications of pathogenicity
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