| RS767393290 |
NDUFS4
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Mitochondrial complex I deficiency |
| RS767393318 |
TGFB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Loeys-Dietz syndrome 4, Familial thoracic aortic aneurysm and aortic dissection |
| RS767395666 |
BARD1
|
Health Risk |
Likely pathogenic |
Familial cancer of breast, Hereditary breast ovarian cancer syndrome |
| RS767395738 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Transitory neonatal diabetes mellitus, Maturity-onset diabetes of the young |
| RS767396631 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group A |
| RS767396820 |
CTSC
|
Health Risk |
Likely pathogenic |
Periodontitis, aggressive 1 |
| RS767398317 |
ANK1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spherocytosis type 1, Hereditary spherocytosis type 1 |
| RS767399660 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS767399782 |
TUBB4A
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypomyelinating leukodystrophy 6, Cerebral palsy |
| RS767399919 |
ADA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of adenosine deaminase 2, Deficiency of adenosine deaminase 2 |
| RS767400155 |
IMPG1
|
Health Risk |
Pathogenic |
— |
| RS767400168 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS767400887 |
EVC
|
Health Risk |
Pathogenic/Likely pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS767400961 |
MYH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Distal arthrogryposis type 2B1, Freeman-Sheldon syndrome |
| RS767402084 |
MUTYH
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS767402215 |
CA5A
|
Health Risk |
Pathogenic |
Hyperammonemic encephalopathy due to carbonic anhydrase VA deficiency, Hyperammonemic encephalopathy due to carbonic anhydrase VA deficiency |
| RS767403321 |
PHYH
|
Health Risk |
Pathogenic |
Phytanic acid storage disease, Retinal dystrophy |
| RS767404024 |
ARX
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, X-linked |
| RS767404055 |
LEPR
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767405408 |
PRKAR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Carney complex, type 1 |
| RS767405535 |
HOGA1
|
Health Risk |
Pathogenic |
Primary hyperoxaluria type 3, Primary hyperoxaluria type 3 |
| RS767406030 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS767406263 |
COQ8A
|
Health Risk |
Likely pathogenic |
Autosomal recessive ataxia due to ubiquinone deficiency, Autosomal recessive ataxia due to ubiquinone deficiency |
| RS767407566 |
TGFBR2
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Familial thoracic aortic aneurysm and aortic dissection, Diabetic retinopathy |
| RS767408144 |
RECQL
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767408748 |
TMEM67
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS767408811 |
STIL
|
Health Risk |
Pathogenic |
— |
| RS767408882 |
CNTNAP2
|
Health Risk |
Likely pathogenic |
Cortical dysplasia-focal epilepsy syndrome, Cortical dysplasia-focal epilepsy syndrome |
| RS767409395 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS767410345 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS767411521 |
CBL
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS767412638 |
ACAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of acetyl-CoA acetyltransferase, Deficiency of acetyl-CoA acetyltransferase |
| RS767412828 |
SLC1A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome, Spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome |
| RS767413799 |
SAMHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 5, Chilblain lupus 2 |
| RS767413852 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS767414081 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS767414809 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS767414907 |
ANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767414973 |
FAM161A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 28, Retinitis pigmentosa |
| RS767415197 |
KMT2D
|
Health Risk |
Pathogenic |
Kabuki syndrome, Kabuki syndrome 1 |
| RS767415886 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS767415935 |
MMP19
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cavitary optic disk anomaly, Familial cavitary optic disk anomaly |
| RS767416221 |
CRB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767416279 |
PCNT
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephalic osteodysplastic primordial dwarfism type II, Microcephalic osteodysplastic primordial dwarfism type II |
| RS767417049 |
ITGB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa with pyloric atresia, Epidermolysis bullosa |
| RS767417979 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 3B, Duchenne muscular dystrophy |
| RS767418586 |
CDK9
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS767419411 |
PPOX
|
Health Risk |
Pathogenic |
Variegate porphyria, childhood-onset |
| RS767422633 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS767423340 |
GABRG2
|
Health Risk |
Conflicting classifications of pathogenicity |
EPILEPSY, CHILDHOOD ABSENCE |
| RS767424476 |
JAK3
|
Health Risk |
Conflicting classifications of pathogenicity |
T-B+ severe combined immunodeficiency due to JAK3 deficiency, JAK3-related disorder |
| RS767424930 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS767425744 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS76742576 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS767426033 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 11, Usher syndrome type 1 |
| RS767426084 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Macrothrombocytopenia, MYH9-related disorder |
| RS767426110 |
TECTA
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767426153 |
CEP290
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Nephronophthisis |
| RS767426819 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767427194 |
C1QBP
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined oxidative phosphorylation deficiency 33, Mitochondrial disease |
| RS767427889 |
PHKG2
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease IXc, Glycogen phosphorylase kinase deficiency |
| RS767428670 |
JAK3
|
Health Risk |
Likely pathogenic |
T-B+ severe combined immunodeficiency due to JAK3 deficiency, Severe combined immunodeficiency disease |
| RS767428982 |
CFB
|
Health Risk |
Conflicting classifications of pathogenicity |
Atypical hemolytic-uremic syndrome with B factor anomaly, Macular degeneration |
| RS767429245 |
TBX20
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS767429459 |
IGSF10
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767430243 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
PCNT-related disorder, PCNT-related disorder |
| RS767430727 |
GPR179
|
Health Risk |
Likely pathogenic |
Congenital stationary night blindness 1E, Congenital stationary night blindness 1E |
| RS767432277 |
CRB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CRB2-related disorder |
| RS767432719 |
CACNA1A
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 42 |
| RS767432973 |
LDLRAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS767433001 |
POLH
|
Health Risk |
Pathogenic/Likely pathogenic |
Xeroderma pigmentosum variant type, Xeroderma pigmentosum |
| RS767433330 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS767433730 |
GCDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Glutaric aciduria, type 1 |
| RS767434859 |
KCNT1
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 14 |
| RS767435344 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS767435461 |
FAN1
|
Health Risk |
Pathogenic |
Karyomegalic interstitial nephritis, Karyomegalic interstitial nephritis |
| RS767435492 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Adams-Oliver syndrome 5 |
| RS767435985 |
SACS
|
Health Risk |
Pathogenic |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS767436158 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS767436221 |
BEST1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767436678 |
RP1
|
Health Risk |
Pathogenic |
Autosomal recessive retinitis pigmentosa, Autosomal recessive retinitis pigmentosa |
| RS767438491 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS767438881 |
PDE6B
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS767441640 |
TMPRSS15
|
Health Risk |
Pathogenic |
— |
| RS767442221 |
RAB23
|
Health Risk |
Conflicting classifications of pathogenicity |
Carpenter syndrome, RAB23-related Carpenter syndrome |
| RS767442358 |
NR2E3
|
Health Risk |
Conflicting classifications of pathogenicity |
Enhanced S-cone syndrome, Retinal dystrophy |
| RS767442671 |
CENPP
|
Health Risk |
Likely pathogenic |
Low-frequency hearing loss, Low-frequency sensorineural hearing impairment |
| RS767443643 |
FANCG
|
Health Risk |
Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group G |
| RS767444397 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS767445373 |
LZTR1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Cardiovascular phenotype |
| RS76744638 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS767447750 |
PEX12
|
Health Risk |
Pathogenic/Likely pathogenic |
Peroxisome biogenesis disorder type 3B, Peroxisome biogenesis disorder 3A (Zellweger) |
| RS767448036 |
SERPINF1
|
Health Risk |
Likely pathogenic |
Osteogenesis imperfecta type 6, Osteogenesis imperfecta type 6 |
| RS767449740 |
TSC2
|
Health Risk |
Pathogenic |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS767449884 |
BBS2
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome 2, Bardet-Biedl syndrome 2 |
| RS767450283 |
DNAAF2
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 10, Primary ciliary dyskinesia |
| RS767450912 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS767451031 |
ABCA4
|
Health Risk |
Pathogenic |
— |
| RS767451281 |
PI4KA
|
Health Risk |
Likely pathogenic |
Polymicrogyria, perisylvian |
| RS767453024 |
PAH
|
Health Risk |
Likely pathogenic |
Phenylketonuria, Phenylketonuria |