| RS767518580 |
BTD
|
Health Risk |
Likely pathogenic |
Biotinidase deficiency, Biotinidase deficiency |
| RS767518932 |
FANCG
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group G |
| RS767520089 |
ANKRD11
|
Health Risk |
Pathogenic |
KBG syndrome, KBG syndrome |
| RS767520227 |
PDE6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS767520406 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS767521281 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS767523458 |
COL9A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epiphyseal dysplasia, multiple |
| RS767523704 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 10 |
| RS767525556 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, Ehlers-Danlos syndrome |
| RS767526540 |
PCDH15
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1F, Usher syndrome type 1F |
| RS767527649 |
HOXD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, Intellectual disability |
| RS767527819 |
ELP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial dysautonomia, ELP1-Associated Medulloblastoma |
| RS767528365 |
RPE65
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy, RPE65-related recessive retinopathy |
| RS767528614 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, Autoinflammatory syndrome |
| RS767529084 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS767529359 |
AUTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autism spectrum disorder due to AUTS2 deficiency, AUTS2-related disorder |
| RS767529587 |
AGL
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS767529592 |
TRIOBP
|
Health Risk |
Likely pathogenic |
TRIOBP-related disorder, TRIOBP-related disorder |
| RS767530768 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS767530943 |
SELENON
|
Health Risk |
Conflicting classifications of pathogenicity |
Eichsfeld type congenital muscular dystrophy, Eichsfeld type congenital muscular dystrophy |
| RS767533378 |
CHRNB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS767533401 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Familial thoracic aortic aneurysm and aortic dissection |
| RS767533596 |
ATM
|
Health Risk |
Pathogenic |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS767533946 |
HLCS
|
Health Risk |
Pathogenic/Likely pathogenic |
Holocarboxylase synthetase deficiency, Inborn genetic diseases |
| RS767534576 |
CACNA1A
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS767534980 |
TIA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Welander distal myopathy, Welander distal myopathy |
| RS767535015 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Smith-Magenis syndrome, Inborn genetic diseases |
| RS76753536 |
APOA5
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial type 5 hyperlipoproteinemia, Hypertriglyceridemia 1 |
| RS767535853 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS76753586 |
PINK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive early-onset Parkinson disease 6, Autosomal recessive early-onset Parkinson disease 6 |
| RS767536068 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Kleefstra syndrome 1 |
| RS767536391 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lynch syndrome 1, Hereditary nonpolyposis colorectal neoplasms |
| RS767536788 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS767537938 |
CARD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to CARD11 deficiency, BENTA disease |
| RS767537996 |
HNF4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 1, Familial hyperinsulinism |
| RS767539005 |
COL7A1
|
Health Risk |
Pathogenic |
Recessive dystrophic epidermolysis bullosa, Epidermolysis bullosa dystrophica |
| RS767539150 |
ZFC3H1
|
Health Risk |
Likely pathogenic |
Short stature, Short stature |
| RS767539728 |
MPDZ
|
Health Risk |
Likely pathogenic |
— |
| RS767540194 |
PDE6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa 43 |
| RS767541018 |
GTF2H5
|
Health Risk |
Likely pathogenic |
— |
| RS767541153 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease, adult type |
| RS767543051 |
ASL
|
Health Risk |
Pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS767543227 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Medulloblastoma |
| RS767543274 |
ERCC2
|
Health Risk |
Likely pathogenic |
Cerebrooculofacioskeletal syndrome 2, Cerebrooculofacioskeletal syndrome 2 |
| RS767543583 |
FBXL4
|
Health Risk |
Likely pathogenic |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS767543623 |
NUBPL
|
Health Risk |
Pathogenic |
Mitochondrial complex I deficiency, nuclear type 21 |
| RS767544239 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS767546831 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Spinocerebellar ataxia |
| RS767546915 |
CSF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse leukoencephalopathy with spheroids, Hereditary diffuse leukoencephalopathy with spheroids |
| RS76754818 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa 25 |
| RS767548512 |
ITGB3
|
Health Risk |
Likely pathogenic |
Glanzmann thrombasthenia, Bleeding disorder |
| RS767548647 |
MCPH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 1, primary |
| RS767548724 |
TGFB3
|
Health Risk |
Likely pathogenic |
Rienhoff syndrome, Arrhythmogenic right ventricular dysplasia 1 |
| RS767549924 |
CTBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767550452 |
CPS1
|
Health Risk |
Likely pathogenic |
Congenital hyperammonemia, type I |
| RS767550455 |
KIF7
|
Health Risk |
Pathogenic |
Acrocallosal syndrome, Acrocallosal syndrome |
| RS767550584 |
HNF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
HNF1A-related disorder, HNF1A-related disorder |
| RS767550929 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS767552861 |
MSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767553206 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767553658 |
ALS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile-onset ascending hereditary spastic paralysis, Infantile-onset ascending hereditary spastic paralysis |
| RS767554181 |
LCA5
|
Health Risk |
Pathogenic/Likely pathogenic |
Leber congenital amaurosis 5, Retinal dystrophy |
| RS767554563 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, POLE-related disorder |
| RS767555361 |
BRWD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767557391 |
EIF2AK4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767558518 |
POLR3B
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism, Charcot-Marie-Tooth disease |
| RS767558735 |
SAMD9
|
Health Risk |
Conflicting classifications of pathogenicity |
Normophosphatemic familial tumoral calcinosis, Monosomy 7 myelodysplasia and leukemia syndrome 2 |
| RS767559716 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS767560143 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS767560639 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS767560852 |
HPS5
|
Health Risk |
Pathogenic |
Hermansky-Pudlak syndrome, Hermansky-Pudlak syndrome |
| RS767560916 |
MYSM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767561828 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 6, Type 2 diabetes mellitus |
| RS767562322 |
RP1L1
|
Health Risk |
Likely pathogenic |
— |
| RS767563000 |
TAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Tyrosinemia type II, Tyrosinemia type II |
| RS767563168 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS767564345 |
TG
|
Health Risk |
Likely pathogenic |
— |
| RS767564445 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Autosomal dominant cerebellar ataxia |
| RS767564684 |
SRD5A2
|
Health Risk |
Pathogenic/Likely pathogenic |
3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency, 3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency |
| RS767564863 |
POLA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767565606 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Peutz-Jeghers syndrome |
| RS767565869 |
GCK
|
Health Risk |
Likely pathogenic |
Maturity-onset diabetes of the young type 2, Monogenic diabetes |
| RS767566180 |
SPTB
|
Health Risk |
Pathogenic |
Hereditary spherocytosis type 2, Hereditary spherocytosis type 2 |
| RS767566761 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS767567119 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767567428 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS767568799 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS767568897 |
LIPT1
|
Health Risk |
Likely pathogenic |
Lipoyl transferase 1 deficiency, Lipoyl transferase 1 deficiency |
| RS767569116 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial meningioma, Hereditary cancer-predisposing syndrome |
| RS767569346 |
XPC
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group C |
| RS767569709 |
KCNMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy-paroxysmal dyskinesia syndrome, Generalized epilepsy-paroxysmal dyskinesia syndrome |
| RS767570081 |
ADGRV1
|
Health Risk |
Pathogenic |
Febrile seizures, familial |
| RS767571327 |
PRDM5
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS767571919 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS767572643 |
SLX4
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS767574122 |
HGSNAT
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 73, Mucopolysaccharidosis |
| RS767575019 |
MCCC2
|
Health Risk |
Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 2 deficiency, Methylcrotonyl-CoA carboxylase deficiency |
| RS767575537 |
TYMP
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial DNA depletion syndrome 1, Mitochondrial DNA depletion syndrome 1 |
| RS767575696 |
CPS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital hyperammonemia, type I |
| RS767576240 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 26, Myofibrillar myopathy 5 |