| RS767219084 |
ARG1
|
Health Risk |
Pathogenic/Likely pathogenic |
Arginase deficiency, Arginase deficiency |
| RS767220480 |
AP4B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 47, Hereditary spastic paraplegia 47 |
| RS767220705 |
AFG2B
|
Health Risk |
Likely pathogenic |
See cases, See cases |
| RS767221160 |
BBS5
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome 5, Bardet-Biedl syndrome |
| RS767221166 |
EMC1
|
Health Risk |
Pathogenic |
— |
| RS767221324 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital muscular dystrophy due to partial LAMA2 deficiency, LAMA2-related muscular dystrophy |
| RS767221835 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS767222404 |
TLE6
|
Health Risk |
Likely pathogenic |
Preimplantation embryonic lethality 1, Preimplantation embryonic lethality 1 |
| RS767224320 |
GP1BA
|
Health Risk |
Likely pathogenic |
Bernard-Soulier syndrome, type A2 |
| RS767225561 |
PPOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767226511 |
DNMT3A
|
Health Risk |
Pathogenic |
— |
| RS767226781 |
OTOGL
|
Health Risk |
Pathogenic |
— |
| RS767228097 |
MYO3A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767229413 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS767230275 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, Intellectual disability |
| RS767230468 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemiplegic migraine, Inborn genetic diseases |
| RS767231715 |
CEP290
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Nephronophthisis |
| RS767231867 |
L2HGDH
|
Health Risk |
Conflicting classifications of pathogenicity |
L-2-hydroxyglutaric aciduria, Inborn genetic diseases |
| RS767231963 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS767232021 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS767232097 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS767232138 |
CFTR
|
Health Risk |
Pathogenic |
Cystic fibrosis, Bronchiectasis with or without elevated sweat chloride 1 |
| RS767234515 |
CPAP
|
Health Risk |
Pathogenic |
— |
| RS767234618 |
CTNNA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 13, Arrhythmogenic right ventricular dysplasia 13 |
| RS767234936 |
BRCA2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS767235227 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767236033 |
DNMT3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Tatton-Brown-Rahman overgrowth syndrome, Tatton-Brown-Rahman overgrowth syndrome |
| RS767236077 |
GALC
|
Health Risk |
Pathogenic/Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS767236217 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS767236339 |
TXNRD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary familial hypertrophic cardiomyopathy, Cardiovascular phenotype |
| RS767236617 |
RNU4ATAC
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteodysplastic primordial dwarfism, type 1 |
| RS767236696 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial meningioma, Hereditary cancer-predisposing syndrome |
| RS76723693 |
G6PD
|
Health Risk |
Pathogenic/Likely pathogenic |
G6PD deficiency, Anemia |
| RS767237510 |
OBSL1
|
Health Risk |
Pathogenic |
3M syndrome 2, OBSL1-related disorder |
| RS767237971 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS767238539 |
ETFDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, ETFDH-related disorder |
| RS767239312 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, Inborn genetic diseases |
| RS767239679 |
MYBPC3
|
Health Risk |
Likely pathogenic |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS767239688 |
TSHR
|
Health Risk |
Likely pathogenic |
Hypothyroidism due to TSH receptor mutations, Sarcoma |
| RS767240266 |
ANKRD26
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombocytopenia 2, Thrombocytopenia 2 |
| RS767240420 |
F11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary factor XI deficiency disease, Plasma factor XI deficiency |
| RS767240461 |
CUL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autism spectrum disorder, Neurodevelopmental disorder with or without autism or seizures |
| RS767241290 |
CPT1A
|
Health Risk |
Pathogenic |
Carnitine palmitoyl transferase 1A deficiency, Carnitine palmitoyl transferase 1A deficiency |
| RS767241917 |
SOX5
|
Health Risk |
Pathogenic/Likely pathogenic |
Lamb-Shaffer syndrome, Lamb-Shaffer syndrome |
| RS767242562 |
CTRC
|
Health Risk |
Pathogenic |
Hereditary pancreatitis, Hereditary pancreatitis |
| RS767243173 |
SNF8
|
Health Risk |
Pathogenic |
SNF8-associated disease, Developmental and epileptic encephalopathy 115 |
| RS767243629 |
CHRNB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS767243766 |
MYH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, proximal |
| RS767245071 |
TYMP
|
Health Risk |
Pathogenic |
Mitochondrial DNA depletion syndrome 1, Mitochondrial neurogastrointestinal encephalomyopathy |
| RS767245568 |
SLC12A6
|
Health Risk |
Pathogenic |
— |
| RS767245893 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS767246037 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS767246053 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS767246962 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia |
| RS767247397 |
GAA
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease, type II |
| RS767247521 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767247726 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS767247980 |
WNK1
|
Health Risk |
Pathogenic |
Neuropathy, hereditary sensory and autonomic |
| RS767247987 |
ERCC6
|
Health Risk |
Pathogenic/Likely pathogenic |
Cockayne syndrome type 2, Cerebrooculofacioskeletal syndrome 1 |
| RS767248510 |
CCM2
|
Health Risk |
Pathogenic/Likely pathogenic |
Cerebral cavernous malformation 2, CCM2-related disorder |
| RS7672497 |
MTTP
|
Health Risk |
Conflicting classifications of pathogenicity |
Abetalipoproteinaemia, Abetalipoproteinaemia |
| RS767249944 |
ETFDH
|
Health Risk |
Pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Glutaric acidemia type 2C |
| RS767250750 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS767250881 |
CEP290
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS767251022 |
CSF3R
|
Health Risk |
Pathogenic |
Autosomal recessive severe congenital neutropenia due to CSF3R deficiency, Autosomal recessive severe congenital neutropenia due to CSF3R deficiency |
| RS767252128 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS767252151 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Ehlers-Danlos syndrome |
| RS767252235 |
FOLR1
|
Health Risk |
Pathogenic |
Cerebral folate transport deficiency, Cerebral folate transport deficiency |
| RS767252448 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS767253467 |
CHEK2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS767254003 |
POLE
|
Health Risk |
Pathogenic |
— |
| RS767255075 |
SLC26A4
|
Health Risk |
Likely pathogenic |
Hearing impairment, Hearing impairment |
| RS767255289 |
FZD4
|
Health Risk |
Pathogenic |
— |
| RS767255426 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group J, Familial cancer of breast |
| RS767255996 |
HELZ2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767257316 |
ATP6V0A2
|
Health Risk |
Pathogenic |
ALG9 congenital disorder of glycosylation, Cutis laxa with osteodystrophy |
| RS767257701 |
IDH3A
|
Health Risk |
Likely pathogenic |
Ovarian serous cystadenocarcinoma, Ovarian serous cystadenocarcinoma |
| RS767257985 |
CHD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767258184 |
RPGR
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS767258350 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS767258629 |
NPR2
|
Health Risk |
Pathogenic |
Acromesomelic dysplasia 1, Maroteaux type |
| RS767258671 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Hematuria |
| RS767258888 |
TMPRSS15
|
Health Risk |
Pathogenic/Likely pathogenic |
Enterokinase deficiency, Enterokinase deficiency |
| RS767259019 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS767259131 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 5 with or without anosmia, CHARGE syndrome |
| RS767259718 |
HSD17B3
|
Health Risk |
Pathogenic |
Testosterone 17-beta-dehydrogenase deficiency, Testosterone 17-beta-dehydrogenase deficiency |
| RS767260373 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS767260608 |
SETBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 29 |
| RS767260655 |
LPL
|
Health Risk |
Likely pathogenic |
Hyperlipoproteinemia, type I |
| RS767261854 |
FLG
|
Health Risk |
Pathogenic/Likely pathogenic |
Dermatitis, atopic |
| RS767262358 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Adams-Oliver syndrome 5 |
| RS76726265 |
TTC21B
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Jeune thoracic dystrophy |
| RS767263669 |
VWA1
|
Health Risk |
Pathogenic |
Neuronopathy, distal hereditary motor |
| RS767263985 |
SLC52A3
|
Health Risk |
Likely pathogenic |
Brown-Vialetto-van Laere syndrome 1, Inborn genetic diseases |
| RS767264288 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS767264426 |
PRMT9
|
Health Risk |
Pathogenic |
Neurodevelopmental abnormality, Neurodevelopmental abnormality |
| RS767264817 |
ZNF513
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767265734 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS767266728 |
DYRK1A
|
Health Risk |
Conflicting classifications of pathogenicity |
DYRK1A-related intellectual disability syndrome, DYRK1A-related intellectual disability syndrome |
| RS767267288 |
B3GALNT2
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a |