HELZ2 Chromosome 20

Helicase with zinc finger 2
1 variant 1 Health Risk

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What This Gene Does
The protein encoded by this gene is a nuclear transcriptional co-activator for peroxisome proliferator activated receptor alpha. The encoded protein contains a zinc finger and is a helicase that appears to be part of the peroxisome proliferator activated receptor alpha interacting complex. This gene is a member of the DNA2/NAM7 helicase gene family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
"Zinc fingers CCCH-type|UPF1 like RNA helicases"
Locus Type
gene with protein product
Location
20q13.33
Ensembl
ENSG00000130589
Key Variants
All Variants (1)
RSID Category Clinical Significance Conditions
RS767255996 Health Risk Conflicting classifications of pathogenicity
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