| RS767036832 |
SAMD9
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767037207 |
F11
|
Health Risk |
Likely pathogenic |
— |
| RS767037296 |
L2HGDH
|
Health Risk |
Conflicting classifications of pathogenicity |
L-2-hydroxyglutaric aciduria, Inborn genetic diseases |
| RS767037992 |
TTC21B
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Nephronophthisis |
| RS767038068 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS767038093 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Vascular disorder, Vascular disorder |
| RS767038098 |
MPDZ
|
Health Risk |
Pathogenic/Likely pathogenic |
Hydrocephalus, nonsyndromic |
| RS767039057 |
MYBPC3
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Hypertrophic cardiomyopathy |
| RS767039732 |
PYGM
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type V |
| RS767041023 |
TUBB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Macrothrombocytopenia, isolated |
| RS767041069 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS767041085 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767041100 |
ACAD8
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of isobutyryl-CoA dehydrogenase, Deficiency of isobutyryl-CoA dehydrogenase |
| RS767041933 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1AA, Primary familial hypertrophic cardiomyopathy |
| RS767042342 |
TTBK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767043399 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS767043440 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS767044154 |
CYP11B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Corticosterone 18-monooxygenase deficiency |
| RS767045134 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe myoclonic epilepsy in infancy, Generalized epilepsy with febrile seizures plus |
| RS767045208 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS767045832 |
EGLN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Erythrocytosis, familial |
| RS767046464 |
CELSR3
|
Health Risk |
Likely pathogenic |
See cases, See cases |
| RS767046669 |
ALOXE3
|
Health Risk |
Pathogenic |
Autosomal recessive congenital ichthyosis 3, Autosomal recessive congenital ichthyosis 3 |
| RS767046886 |
ETFDH
|
Health Risk |
Pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Glutaric acidemia type 2C |
| RS767047134 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
RAI1-related disorder, Inborn genetic diseases |
| RS767048520 |
AFF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767048737 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Hereditary spastic paraplegia |
| RS767048858 |
CHRNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal multiple pterygium syndrome, Lethal multiple pterygium syndrome |
| RS767049254 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Distal myopathy with anterior tibial onset |
| RS767050469 |
COL4A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Porencephaly 2, Porencephaly 2 |
| RS767050911 |
CDK10
|
Health Risk |
Pathogenic |
Al Kaissi syndrome, Al Kaissi syndrome |
| RS767051948 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa pruriginosa, Epidermolysis bullosa pruriginosa |
| RS767052015 |
GRHPR
|
Health Risk |
Pathogenic |
Primary hyperoxaluria, type II |
| RS767052156 |
CACNA1S
|
Health Risk |
Pathogenic/Likely pathogenic |
Malignant hyperthermia, susceptibility to |
| RS767052591 |
SCN3A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS76705400 |
MCM7
|
Health Risk |
Pathogenic |
Meier-Gorlin syndrome, Meier-Gorlin syndrome |
| RS767054899 |
KIF22
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS767055284 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767056243 |
RARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pontocerebellar hypoplasia type 6, Pontocerebellar hypoplasia type 6 |
| RS767057323 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH9-related disorder, MYH9-related disorder |
| RS767058690 |
SHANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, SHANK3-related disorder |
| RS767059758 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS767060533 |
GSDME
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 5, Autosomal dominant nonsyndromic hearing loss 5 |
| RS767060858 |
KYNU
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital NAD deficiency disorder, Vertebral |
| RS767061831 |
IDH2
|
Health Risk |
Likely pathogenic |
D-2-hydroxyglutaric aciduria 2, D-2-hydroxyglutaric aciduria 2 |
| RS767062387 |
MRPS16
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767063118 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS767063709 |
TYMP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767063791 |
ACADVL
|
Health Risk |
Conflicting classifications of pathogenicity |
Very long chain acyl-CoA dehydrogenase deficiency, ACADVL-related disorder |
| RS767065263 |
TMEM126B
|
Health Risk |
Likely pathogenic |
TMEM126B-related disorder, Mitochondrial complex I deficiency |
| RS767066842 |
RTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, RTN2-related disorder |
| RS767066938 |
DHTKD1
|
Health Risk |
Likely pathogenic |
2-aminoadipic 2-oxoadipic aciduria, 2-aminoadipic 2-oxoadipic aciduria |
| RS767067922 |
SPTAN1
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 5 |
| RS767068264 |
PLOD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, kyphoscoliotic type 1 |
| RS767068756 |
BBS12
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 12, Bardet-Biedl syndrome |
| RS767069606 |
CHCHD10
|
Health Risk |
Conflicting classifications of pathogenicity |
Lower motor neuron syndrome with late-adult onset, Frontotemporal dementia and/or amyotrophic lateral sclerosis 2 |
| RS767069721 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS767070218 |
BMPR2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pulmonary hypertension, primary |
| RS76707172 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS767071793 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS767071930 |
SYNGAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 5 |
| RS767072775 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS767072839 |
EVC2
|
Health Risk |
Pathogenic/Likely pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS767072861 |
SRPX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Rolandic epilepsy, intellectual disability |
| RS767073232 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Inborn genetic diseases |
| RS767073368 |
PCLO
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767074039 |
GATA3
|
Health Risk |
Pathogenic |
Hypoparathyroidism, deafness |
| RS767074176 |
ADAMTS17
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani 4 syndrome, recessive |
| RS767074769 |
AGL
|
Health Risk |
Likely pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS767075044 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 5, Charcot-Marie-Tooth disease dominant intermediate E |
| RS767075372 |
MID1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767075719 |
PAH
|
Health Risk |
Conflicting classifications of pathogenicity |
Phenylketonuria, Phenylketonuria |
| RS767076281 |
SIK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 30 |
| RS767077707 |
ADAMTS17
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani 4 syndrome, recessive |
| RS767078097 |
MEN1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia |
| RS767078182 |
SLC30A9
|
Health Risk |
Conflicting classifications of pathogenicity |
Psychomotor regression-oculomotor apraxia-movement disorder-nephropathy syndrome, Inborn genetic diseases |
| RS767078596 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1AA, Primary familial hypertrophic cardiomyopathy |
| RS767078773 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS767078782 |
USH2A
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 39, Usher syndrome type 2A |
| RS767078847 |
CUBN
|
Health Risk |
Pathogenic/Likely pathogenic |
Proteinuria, chronic benign |
| RS767079113 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Arthrogryposis multiplex congenita 6, Nemaline myopathy 2 |
| RS767079173 |
FMO3
|
Health Risk |
Pathogenic/Likely pathogenic |
Trimethylaminuria, Trimethylaminuria |
| RS767079858 |
TRPV4
|
Health Risk |
Pathogenic |
TRPV4-related bone disorder, TRPV4-related bone disorder |
| RS767080621 |
SIN3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767081312 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767081660 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
FN1-related disorder, Glomerulopathy with fibronectin deposits 2 |
| RS767083273 |
COL17A1
|
Health Risk |
Pathogenic |
— |
| RS767083685 |
CNGA3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767084290 |
MYH14
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH14-related disorder, MYH14-related disorder |
| RS767084483 |
SKIC2
|
Health Risk |
Pathogenic |
Immunodeficiency 57, Immunodeficiency 57 |
| RS767084659 |
NBAS
|
Health Risk |
Pathogenic/Likely pathogenic |
Short stature-optic atrophy-Pelger-Huët anomaly syndrome, Infantile liver failure syndrome 2 |
| RS767086146 |
WDR73
|
Health Risk |
Pathogenic |
Galloway-Mowat syndrome 1, Galloway-Mowat syndrome 1 |
| RS767086387 |
MANBA
|
Health Risk |
Likely pathogenic |
Beta-D-mannosidosis, Lung cancer |
| RS767086409 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS767086502 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Bloom syndrome |
| RS76708715 |
LPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperlipoproteinemia, type I |
| RS767087695 |
COL4A5
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked Alport syndrome, X-linked Alport syndrome |
| RS767088341 |
NPRL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, familial focal |
| RS767088377 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH9-related disorder, Autosomal dominant nonsyndromic hearing loss 17 |
| RS767088664 |
IGHMBP2
|
Health Risk |
Pathogenic |
Autosomal recessive distal spinal muscular atrophy 1, Charcot-Marie-Tooth disease axonal type 2S |