| RS766900840 |
LTBP3
|
Health Risk |
Likely pathogenic |
Brachyolmia-amelogenesis imperfecta syndrome, Brachyolmia-amelogenesis imperfecta syndrome |
| RS766900945 |
COL4A3
|
Health Risk |
Pathogenic |
Autosomal recessive Alport syndrome, Autosomal dominant Alport syndrome |
| RS766900991 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 6, WFS1-Related Spectrum Disorders |
| RS766901049 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS766901538 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia type 4, Hereditary cancer-predisposing syndrome |
| RS766902987 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa dystrophica, Recessive dystrophic epidermolysis bullosa |
| RS766904735 |
MLH1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS766905791 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Gorlin syndrome |
| RS766905993 |
MSH6
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Lynch syndrome 5 |
| RS766906034 |
ATP7B
|
Health Risk |
Pathogenic |
Wilson disease, Wilson disease |
| RS766906353 |
CDH23
|
Health Risk |
Likely pathogenic |
— |
| RS766907011 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766907687 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS766908402 |
NDUFS1
|
Health Risk |
Likely pathogenic |
— |
| RS766908700 |
BMPR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Juvenile polyposis syndrome, Hereditary cancer-predisposing syndrome |
| RS766909163 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Inborn genetic diseases |
| RS76690956 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS766910280 |
SCN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy with febrile seizures plus, type 1 |
| RS766911756 |
PIEZO2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766913050 |
COMP
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple epiphyseal dysplasia type 1, Pseudoachondroplastic spondyloepiphyseal dysplasia syndrome |
| RS766913051 |
MRPS22
|
Health Risk |
Pathogenic |
— |
| RS766913143 |
MPDZ
|
Health Risk |
Pathogenic |
— |
| RS766914147 |
ARSB
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis type 6, Mucopolysaccharidosis type 6 |
| RS766915154 |
FH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fumarase deficiency |
| RS766915366 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS766915522 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2, Retinitis pigmentosa 39 |
| RS766916450 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS766917452 |
CTRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pancreatitis, Hereditary pancreatitis |
| RS766917640 |
CAPN3
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Muscular dystrophy |
| RS766919534 |
UMOD
|
Health Risk |
Pathogenic |
Autosomal dominant medullary cystic kidney disease with or without hyperuricemia, Familial juvenile hyperuricemic nephropathy type 1 |
| RS766920034 |
CD36
|
Health Risk |
Pathogenic/Likely pathogenic |
Malaria, susceptibility to |
| RS766920075 |
LAMA2
|
Health Risk |
Pathogenic/Likely pathogenic |
LAMA2-related muscular dystrophy, Merosin deficient congenital muscular dystrophy |
| RS766920772 |
SH3PXD2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Frank-Ter Haar syndrome, Frank-Ter Haar syndrome |
| RS766921114 |
EIF2B5
|
Health Risk |
Conflicting classifications of pathogenicity |
Vanishing white matter disease, Leukoencephalopathy with vanishing white matter 5 |
| RS766921341 |
ABCC8
|
Health Risk |
Pathogenic |
Hyperinsulinemic hypoglycemia, familial |
| RS766922403 |
DNAH11
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, DNAH11-related disorder |
| RS766922669 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766925398 |
SNTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS766925936 |
HYCC1
|
Health Risk |
Likely pathogenic |
Hypomyelination and Congenital Cataract, Hypomyelination and Congenital Cataract |
| RS766926330 |
FAM20A
|
Health Risk |
Pathogenic |
Amelogenesis imperfecta type 1G, Amelogenesis imperfecta type 1G |
| RS766926614 |
SYNPO
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766929091 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS766929334 |
SKI
|
Health Risk |
Conflicting classifications of pathogenicity |
Shprintzen-Goldberg syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS766931184 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS766931727 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental delay, Neurodevelopmental delay |
| RS766931948 |
NEMF
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with speech delay and axonal peripheral neuropathy, Intellectual developmental disorder with speech delay and axonal peripheral neuropathy |
| RS766932828 |
UBA5
|
Health Risk |
Pathogenic |
Inborn genetic diseases, UBA5-related disorder |
| RS766933370 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS766934517 |
TNNT1
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 5, Nemaline myopathy 5 |
| RS766934707 |
TXNRD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Cardiovascular phenotype |
| RS766935145 |
TRMT5
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation defect type 26, Combined oxidative phosphorylation defect type 26 |
| RS766935265 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Myopathy |
| RS766935285 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS766935302 |
GBE1
|
Health Risk |
Pathogenic/Likely pathogenic |
GBE1-related disorder, Glycogen storage disease |
| RS766936914 |
DYSF
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS766938111 |
SGSH
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis, MPS-III-A |
| RS766938558 |
MITF
|
Health Risk |
Conflicting classifications of pathogenicity |
Tietz syndrome, Melanoma |
| RS766938849 |
EVC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS766939282 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS766941804 |
DNAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS766942126 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, Menke-Hennekam syndrome 1 |
| RS766942777 |
NRXN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Chromosome 2p16.3 deletion syndrome, Pitt-Hopkins-like syndrome 2 |
| RS766943204 |
RPGRIP1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS766943894 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS766944483 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS766944646 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS766945413 |
GSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Finnish type amyloidosis, Inborn genetic diseases |
| RS766945794 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS766945871 |
SMPD1
|
Health Risk |
Likely pathogenic |
Niemann-Pick disease, type B |
| RS766945941 |
SLC6A1
|
Health Risk |
Likely pathogenic |
Epilepsy with myoclonic atonic seizures, Epilepsy with myoclonic atonic seizures |
| RS766946947 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 6 |
| RS766947924 |
PEX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Zellweger spectrum disorders, Heimler syndrome 1 |
| RS766948560 |
RP1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Occult macular dystrophy |
| RS766949012 |
SUOX
|
Health Risk |
Likely pathogenic |
Sulfite oxidase deficiency, Sulfite oxidase deficiency |
| RS766950362 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS766950664 |
KLHL7
|
Health Risk |
Likely pathogenic |
— |
| RS766950975 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS766951637 |
NEFL
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 2E, Charcot-Marie-Tooth disease type 2E |
| RS766952056 |
CEP290
|
Health Risk |
Likely pathogenic |
Nephronophthisis, Joubert syndrome |
| RS766953315 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary familial hypertrophic cardiomyopathy, Dilated cardiomyopathy 1AA |
| RS766956053 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, ARID1B-related disorder |
| RS766956834 |
TRAPPC2L
|
Health Risk |
Likely pathogenic |
Encephalopathy, progressive |
| RS766956862 |
HNF1A
|
Health Risk |
Pathogenic |
Monogenic diabetes, Maturity-onset diabetes of the young |
| RS766957571 |
VPS13A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766958608 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS766958827 |
PLEKHG2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766959096 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS766959653 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766960979 |
CDK10
|
Health Risk |
Pathogenic/Likely pathogenic |
Al Kaissi syndrome, Inborn genetic diseases |
| RS766962106 |
PCDH19
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 9 |
| RS766962315 |
LAMP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Danon disease, Cardiovascular phenotype |
| RS766962416 |
AGRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 8, Congenital myasthenic syndrome 8 |
| RS766962462 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS766964098 |
KCNMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy-paroxysmal dyskinesia syndrome, Generalized epilepsy-paroxysmal dyskinesia syndrome |
| RS766964585 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS766965358 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS766966542 |
SLC25A20
|
Health Risk |
Conflicting classifications of pathogenicity |
Carnitine acylcarnitine translocase deficiency, SLC25A20-related disorder |
| RS766968609 |
MCM3AP
|
Health Risk |
Pathogenic |
— |
| RS766968771 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS766969099 |
PDSS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deafness-encephaloneuropathy-obesity-valvulopathy syndrome, Deafness-encephaloneuropathy-obesity-valvulopathy syndrome |