| RS766704468 |
HNF1A
|
Health Risk |
Pathogenic |
— |
| RS766705070 |
MAP3K7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766705843 |
CPS1
|
Health Risk |
Likely pathogenic |
Congenital hyperammonemia, type I |
| RS766706861 |
ATM
|
Health Risk |
Pathogenic/Likely pathogenic |
Ataxia-telangiectasia syndrome, Familial cancer of breast |
| RS766707325 |
DNAH8
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Spermatogenic failure 46 |
| RS766709333 |
RP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinitis pigmentosa 1 |
| RS766709360 |
UTRN
|
Health Risk |
Likely pathogenic |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS766709484 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS766709743 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS766710257 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS766710382 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS766711286 |
SACS
|
Health Risk |
Pathogenic |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS766711342 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS766711908 |
SLC4A11
|
Health Risk |
Conflicting classifications of pathogenicity |
Corneal dystrophy, Corneal dystrophy |
| RS766712618 |
TREM2
|
Health Risk |
Pathogenic |
Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2, Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2 |
| RS766712653 |
CLCN7
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteopetrosis, Osteopetrosis |
| RS766713582 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary cancer-predisposing syndrome |
| RS766713665 |
EYA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Branchiootic syndrome 1, Branchiootorenal syndrome 1 |
| RS766714128 |
HGD
|
Health Risk |
Pathogenic |
Alkaptonuria, Alkaptonuria |
| RS766714463 |
DARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukoencephalopathy with brain stem and spinal cord involvement-high lactate syndrome, Leukoencephalopathy with brain stem and spinal cord involvement-high lactate syndrome |
| RS766715445 |
FREM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 2, Isolated cryptophthalmia |
| RS766715882 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Retinitis pigmentosa |
| RS766716563 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Dystrophin deficiency |
| RS766717305 |
GALNT3
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumoral calcinosis, hyperphosphatemic |
| RS766719443 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Tuberous sclerosis syndrome |
| RS766719764 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Ectopia lentis 1 |
| RS766719790 |
TRPV6
|
Health Risk |
Pathogenic |
Hyperparathyroidism, transient neonatal |
| RS766720269 |
APC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766720790 |
ASPA
|
Health Risk |
Pathogenic/Likely pathogenic |
Spongy degeneration of central nervous system, Canavan Disease |
| RS766721028 |
JPH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS766721811 |
MMUT
|
Health Risk |
Likely pathogenic |
— |
| RS766723466 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 3B, Duchenne muscular dystrophy |
| RS766724096 |
PLOD1
|
Health Risk |
Pathogenic |
Ehlers-Danlos syndrome, kyphoscoliotic type 1 |
| RS766724527 |
TPM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy 3 |
| RS766724697 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS766726309 |
TCF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Pitt-Hopkins syndrome, Pitt-Hopkins syndrome |
| RS766727694 |
NF1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS766727876 |
ACADM
|
Health Risk |
Likely pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS766728475 |
HSPB1
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease axonal type 2F, Charcot-Marie-Tooth disease axonal type 2F |
| RS766728732 |
MYH14
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 4A, Hearing impairment |
| RS766730487 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS766730954 |
SCN9A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Neuropathy |
| RS766730980 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolfram syndrome 1, Wolfram syndrome 1 |
| RS766731755 |
ELAC2
|
Health Risk |
Pathogenic |
Prostate cancer, hereditary |
| RS766732875 |
PIGN
|
Health Risk |
Likely pathogenic |
Multiple congenital anomalies-hypotonia-seizures syndrome 1, Multiple congenital anomalies-hypotonia-seizures syndrome 1 |
| RS766733097 |
WRN
|
Health Risk |
Pathogenic/Likely pathogenic |
Werner syndrome, Werner syndrome |
| RS766733439 |
GYS2
|
Health Risk |
Likely pathogenic |
Glycogen storage disorder due to hepatic glycogen synthase deficiency, Glycogen storage disorder due to hepatic glycogen synthase deficiency |
| RS766734761 |
SMARCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766734961 |
ACTA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 6 |
| RS766735610 |
RAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency with skin granulomas, Histiocytic medullary reticulosis |
| RS766735856 |
SLC34A2
|
Health Risk |
Pathogenic |
— |
| RS766735977 |
OTC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS766736390 |
NSD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766739164 |
APC
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, APC-related disorder |
| RS766740575 |
ABCA4
|
Health Risk |
Pathogenic/Likely pathogenic |
Stargardt disease, Stargardt disease |
| RS766740877 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS766741057 |
BMPR2
|
Health Risk |
Likely pathogenic |
— |
| RS766741204 |
BBS12
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 12, Bardet-Biedl syndrome |
| RS766741890 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS766742117 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS766742720 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS766743441 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766745103 |
TBC1D24
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial infantile myoclonic epilepsy, Inborn genetic diseases |
| RS766745289 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Cardiovascular phenotype |
| RS766745748 |
NCF2
|
Health Risk |
Pathogenic/Likely pathogenic |
Granulomatous disease, chronic |
| RS766745955 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS766746479 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, DMD-related disorder |
| RS766746657 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS766747354 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, CHARGE syndrome |
| RS766747626 |
CHD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy 94, Developmental and epileptic encephalopathy 94 |
| RS766748586 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS766748789 |
TJP2
|
Health Risk |
Likely pathogenic |
Cholestasis, progressive familial intrahepatic |
| RS766749712 |
LRRC8A
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS766750282 |
GALNT3
|
Health Risk |
Pathogenic |
Tumoral calcinosis, hyperphosphatemic |
| RS766750333 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, type 4 |
| RS76675173 |
PAX2
|
Health Risk |
Pathogenic |
Renal coloboma syndrome, Renal coloboma syndrome |
| RS766751878 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, Cardiac arrhythmia |
| RS76675246 |
YY1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gabriele de Vries syndrome, Gabriele de Vries syndrome |
| RS766753209 |
PLEKHG5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS766753795 |
MCCC2
|
Health Risk |
Pathogenic/Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 2 deficiency, Methylcrotonyl-CoA carboxylase deficiency |
| RS766753906 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-onset myopathy with fatal cardiomyopathy, Tibial muscular dystrophy |
| RS766753922 |
OTOGL
|
Health Risk |
Pathogenic/Likely pathogenic |
Rare genetic deafness, Autosomal recessive nonsyndromic hearing loss 84B |
| RS766754092 |
SPINK5
|
Health Risk |
Pathogenic/Likely pathogenic |
Ichthyosis linearis circumflexa, Netherton syndrome |
| RS766754598 |
SDHD
|
Health Risk |
Conflicting classifications of pathogenicity |
Cowden syndrome 3, Carney-Stratakis syndrome |
| RS766755156 |
ACADVL
|
Health Risk |
Conflicting classifications of pathogenicity |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS766755439 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS766756026 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS766758560 |
INSR
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766759197 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS766759466 |
NSD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766760388 |
POLR1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Treacher Collins syndrome 3, Treacher Collins syndrome 3 |
| RS766762597 |
ERF
|
Health Risk |
Conflicting classifications of pathogenicity |
Lambdoidal craniosynostosis, Lambdoidal craniosynostosis |
| RS766762599 |
GALC
|
Health Risk |
Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS766762684 |
CTSF
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis 13, Neuronal ceroid lipofuscinosis 13 |
| RS766762760 |
GLDC
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy 1 |
| RS766764090 |
ACSF3
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS766765538 |
ITGB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766767235 |
PDE6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS766767855 |
PHOX2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital central hypoventilation, Hereditary cancer-predisposing syndrome |
| RS766768359 |
HCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |