| RS766521030 |
XYLT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Desbuquois dysplasia 1, XYLT1-related disorder |
| RS766521182 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
POLG-related disorder, Progressive sclerosing poliodystrophy |
| RS766522109 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS766522434 |
FYCO1
|
Health Risk |
Likely pathogenic |
Cataract 18, Cataract 18 |
| RS766524048 |
PPM1D
|
Health Risk |
Pathogenic |
— |
| RS766524637 |
NPHP1
|
Health Risk |
Pathogenic |
Nephronophthisis 1, Nephronophthisis |
| RS766525712 |
NCF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Granulomatous disease, chronic |
| RS766527083 |
MAK
|
Health Risk |
Likely pathogenic |
— |
| RS766527634 |
SAMD11
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766528289 |
ALDH7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyridoxine-dependent epilepsy, Pyridoxine-dependent epilepsy |
| RS766529852 |
CSPP1
|
Health Risk |
Pathogenic |
Joubert syndrome 21, Joubert syndrome 21 |
| RS766530086 |
CARD9
|
Health Risk |
Likely pathogenic |
Predisposition to invasive fungal disease due to CARD9 deficiency, Predisposition to invasive fungal disease due to CARD9 deficiency |
| RS766530579 |
PNKP
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 12 |
| RS766531368 |
PTPN11
|
Health Risk |
Uncertain significance; risk factor |
Werner syndrome, RASopathy |
| RS766532148 |
ACADM
|
Health Risk |
Conflicting classifications of pathogenicity |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Inborn genetic diseases |
| RS766532363 |
TNFRSF6B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766533641 |
ADGRG1
|
Health Risk |
Pathogenic |
— |
| RS766533795 |
ATM
|
Health Risk |
Pathogenic/Likely pathogenic |
Ataxia-telangiectasia syndrome, Familial cancer of breast |
| RS766533982 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS766535034 |
DPYD
|
Health Risk |
Likely pathogenic |
Dihydropyrimidine dehydrogenase deficiency, Dihydropyrimidine dehydrogenase deficiency |
| RS766536002 |
ARHGEF10
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766536174 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS766536350 |
AGL
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease type III, Glycogen storage disease IIIa |
| RS766536479 |
UGT1A1
|
Health Risk |
Pathogenic |
Crigler-Najjar syndrome, Crigler-Najjar syndrome |
| RS766538692 |
POLE
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial colorectal cancer type X |
| RS766538754 |
CIITA
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class II deficiency, MHC class II deficiency |
| RS766539394 |
ADA
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency, autosomal recessive |
| RS766539773 |
FRAS1
|
Health Risk |
Pathogenic |
Renal agenesis, Renal agenesis |
| RS766539793 |
RORB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766540386 |
RINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766540875 |
ADAMTSL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Ectopia lentis et pupillae, Ectopia lentis 2 |
| RS766541549 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, CFTR-related disorder |
| RS766541647 |
CPLANE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Orofaciodigital syndrome type 6, Joubert syndrome 17 |
| RS766541836 |
DNMT3B
|
Health Risk |
Pathogenic |
Centromeric instability of chromosomes 1, 9 and 16 and immunodeficiency |
| RS766541944 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome type 1D |
| RS766541995 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Ehlers-Danlos syndrome |
| RS766542090 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CHARGE syndrome |
| RS766542823 |
AAAS
|
Health Risk |
Pathogenic |
Glucocorticoid deficiency with achalasia, Glucocorticoid deficiency with achalasia |
| RS766543331 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Inborn genetic diseases |
| RS766543419 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS766543785 |
ATP2B4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766544188 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hearing impairment, Hearing impairment |
| RS766545577 |
TYRP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculocutaneous albinism type 3, MELANESIAN BLOND HAIR |
| RS766545876 |
DIAPH1
|
Health Risk |
Pathogenic |
Autosomal dominant nonsyndromic hearing loss 1, Progressive microcephaly-seizures-cortical blindness-developmental delay syndrome |
| RS766546584 |
ADSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Adenylosuccinate lyase deficiency, Inborn genetic diseases |
| RS766547457 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS766547643 |
HARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 3B, Usher syndrome type 3B |
| RS766548165 |
SLC5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial renal glucosuria, Familial renal glucosuria |
| RS766548696 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Birt-Hogg-Dube syndrome |
| RS766549271 |
KCNV2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766550724 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Autosomal dominant Alport syndrome |
| RS766551395 |
SLC25A20
|
Health Risk |
Pathogenic |
Carnitine acylcarnitine translocase deficiency, Carnitine acylcarnitine translocase deficiency |
| RS766551411 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS766553671 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS766553685 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS766553845 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 2, Hereditary cancer-predisposing syndrome |
| RS766555082 |
IL7R
|
Health Risk |
Likely pathogenic |
Immunodeficiency 104, Immunodeficiency 104 |
| RS766555353 |
SLC22A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal carnitine transport defect, Decreased circulating carnitine concentration |
| RS766555879 |
NDUFV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leigh syndrome, Mitochondrial complex I deficiency |
| RS76655666 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 7 |
| RS766556930 |
GPSM2
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS766557412 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS766557450 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS766558667 |
MACF1
|
Health Risk |
Likely pathogenic |
Lissencephaly 9 with complex brainstem malformation, Lissencephaly 9 with complex brainstem malformation |
| RS766559629 |
OBSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
3M syndrome 2, 3M syndrome 2 |
| RS766560578 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS766560974 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS766561921 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH7-related skeletal myopathy, Hypertrophic cardiomyopathy 1 |
| RS766562951 |
HNRNPK
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766563354 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS766564988 |
OTOGL
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 84B, OTOGL-related disorder |
| RS766565506 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS766565738 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS766567785 |
FANCD2
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia complementation group D2 |
| RS766567944 |
SLC4A11
|
Health Risk |
Likely pathogenic |
Corneal dystrophy-perceptive deafness syndrome, Congenital hereditary endothelial dystrophy of cornea |
| RS766568333 |
KIZ
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 69, Retinitis pigmentosa 69 |
| RS766569322 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS766569890 |
SKI
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Shprintzen-Goldberg syndrome |
| RS766570103 |
PTEN
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, PTEN hamartoma tumor syndrome |
| RS766570903 |
ABCA4
|
Health Risk |
Likely pathogenic |
Severe early-childhood-onset retinal dystrophy, Retinal dystrophy |
| RS766571996 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS766572502 |
ARMC9
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome 30, Joubert syndrome 30 |
| RS766572560 |
SLC26A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Pendred syndrome, Autosomal recessive nonsyndromic hearing loss 4 |
| RS766572561 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS766573431 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS766573679 |
ABCC2
|
Health Risk |
Pathogenic |
Dubin-Johnson syndrome, Dubin-Johnson syndrome |
| RS766574538 |
PEX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, Peroxisome biogenesis disorder |
| RS76657474 |
LRTOMT
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 63, LRTOMT-related disorder |
| RS766574778 |
IDUA
|
Health Risk |
Pathogenic |
Hurler syndrome, Mucopolysaccharidosis |
| RS766574854 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS766574975 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Landau-Kleffner syndrome |
| RS766574999 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766575263 |
RAB27A
|
Health Risk |
Pathogenic |
Griscelli syndrome type 2, Griscelli syndrome type 2 |
| RS766575601 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 5 with or without anosmia, CHARGE syndrome |
| RS766575963 |
SMCHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Facioscapulohumeral muscular dystrophy 2, SMCHD1-related disorder |
| RS766576144 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS766576246 |
VHL
|
Health Risk |
Conflicting classifications of pathogenicity |
Von Hippel-Lindau syndrome, Chuvash polycythemia |
| RS766577671 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS766579880 |
ACADS
|
Health Risk |
Likely pathogenic |
Deficiency of butyryl-CoA dehydrogenase, ACADS-related disorder |
| RS766580034 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Distal myopathy with posterior leg and anterior hand involvement, Myofibrillar myopathy 5 |