| RS766471384 |
CUL7
|
Health Risk |
Likely pathogenic |
3M syndrome 1, 3M syndrome 1 |
| RS766472184 |
CYFIP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766472965 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766473931 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS766473954 |
TGFBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Loeys-Dietz syndrome 2 |
| RS766474188 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypercholesterolemia, Familial hypercholesterolemia |
| RS766474320 |
BLM
|
Health Risk |
Pathogenic |
Bloom syndrome, Bloom syndrome |
| RS766474711 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS766474846 |
C1S
|
Health Risk |
Pathogenic |
— |
| RS766474996 |
HSD3B2
|
Health Risk |
Pathogenic |
3 beta-Hydroxysteroid dehydrogenase deficiency, 3 beta-Hydroxysteroid dehydrogenase deficiency |
| RS766475725 |
WDR19
|
Health Risk |
Conflicting classifications of pathogenicity |
Cranioectodermal dysplasia 4, Asphyxiating thoracic dystrophy 5 |
| RS766476582 |
BTD
|
Health Risk |
Pathogenic/Likely pathogenic |
Biotinidase deficiency, Biotinidase deficiency |
| RS766476590 |
LZTR1
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS76647672 |
SLCO1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Rotor syndrome, Rotor syndrome |
| RS766478019 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS766478634 |
MED23
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal recessive 18 |
| RS766478911 |
TCN2
|
Health Risk |
Pathogenic |
Transcobalamin II deficiency, Transcobalamin II deficiency |
| RS766479402 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Isolated Nonsyndromic Congenital Heart Disease |
| RS766480693 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766481283 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS766481385 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia |
| RS766482965 |
COASY
|
Health Risk |
Pathogenic/Likely pathogenic |
Pontocerebellar hypoplasia, type 12 |
| RS766483138 |
PEX6
|
Health Risk |
Pathogenic/Likely pathogenic |
Peroxisome biogenesis disorder 4A (Zellweger), Peroxisome biogenesis disorder 4B |
| RS766483254 |
MYO18B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS76648342 |
SALL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Duane-radial ray syndrome, SALL4-related disorder |
| RS766483572 |
C9
|
Health Risk |
Pathogenic |
— |
| RS766484260 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Cardiovascular phenotype |
| RS766484375 |
PCDH15
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1F, Autosomal recessive nonsyndromic hearing loss 23 |
| RS766484593 |
PCARE
|
Health Risk |
Pathogenic |
— |
| RS766484806 |
VPS13B
|
Health Risk |
Pathogenic |
Cohen syndrome, Cohen syndrome |
| RS766485109 |
FREM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculotrichoanal syndrome, BNAR syndrome |
| RS766485358 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, FG syndrome |
| RS766486676 |
SDHC
|
Health Risk |
Conflicting classifications of pathogenicity |
Pheochromocytoma/paraganglioma syndrome 3, Gastrointestinal stromal tumor |
| RS766487204 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS766487430 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS766487534 |
EIF2B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Vanishing white matter disease, Vanishing white matter disease |
| RS766488017 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Ullrich congenital muscular dystrophy 1A |
| RS766488520 |
AMHR2
|
Health Risk |
Likely pathogenic |
— |
| RS766488722 |
RAX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 6, Cone-rod dystrophy 11 |
| RS766488790 |
TYK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 35, Immunodeficiency 35 |
| RS766490931 |
GABRA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, idiopathic generalized |
| RS766491340 |
SLC6A19
|
Health Risk |
Conflicting classifications of pathogenicity |
Neutral 1 amino acid transport defect, Neutral 1 amino acid transport defect |
| RS766491471 |
USH2A
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 39, Usher syndrome type 2A |
| RS766491693 |
SERPING1
|
Health Risk |
Likely pathogenic |
Hereditary angioedema type 1, Hereditary angioedema type 1 |
| RS766491800 |
LAMP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Danon disease, Cardiovascular phenotype |
| RS766491965 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 5 |
| RS766492523 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS766492897 |
BSCL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital generalized lipodystrophy type 2, Neuronopathy |
| RS766493088 |
CLN6
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis, Neuronal ceroid lipofuscinosis |
| RS766494934 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS76649554 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS766495775 |
DHCR7
|
Health Risk |
Likely pathogenic |
Smith-Lemli-Opitz syndrome, DHCR7-related disorder |
| RS766496010 |
DUOX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Thyroid dyshormonogenesis 6, Thyroid dyshormonogenesis 6 |
| RS766496842 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS766496861 |
MBD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766497093 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary nonpolyposis colorectal neoplasms |
| RS76649725 |
CFTR
|
Health Risk |
Pathogenic |
Cystic fibrosis, CFTR-related disorder |
| RS766497653 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS766499417 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS766499430 |
SYNE1
|
Health Risk |
Pathogenic |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS766500689 |
EDARADD
|
Health Risk |
Pathogenic |
Ectodermal dysplasia 11B, hypohidrotic/hair/tooth type |
| RS766501515 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Hematuria |
| RS766501537 |
ALAD
|
Health Risk |
Conflicting classifications of pathogenicity |
Porphobilinogen synthase deficiency, Inborn genetic diseases |
| RS766502564 |
MYPN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1KK, Congenital myopathy |
| RS766503699 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS766503812 |
COL11A2
|
Health Risk |
Pathogenic |
— |
| RS766504293 |
GATA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Monocytopenia with susceptibility to infections, Deafness-lymphedema-leukemia syndrome |
| RS766504801 |
ABCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCC6-related disorder, Arterial calcification |
| RS766504984 |
CTSC
|
Health Risk |
Pathogenic/Likely pathogenic |
Papillon-Lefèvre syndrome, Periodontitis |
| RS766505643 |
ITGB4
|
Health Risk |
Pathogenic |
— |
| RS766505885 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Usher syndrome |
| RS766506181 |
DNMT3A
|
Health Risk |
Likely pathogenic |
Tatton-Brown-Rahman overgrowth syndrome, Tatton-Brown-Rahman overgrowth syndrome |
| RS766506778 |
CUL4B
|
Health Risk |
Pathogenic |
— |
| RS766508393 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766508656 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Medulloblastoma |
| RS766509602 |
GBA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia, Spastic paraplegia |
| RS766509980 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766510287 |
TRAPPC2L
|
Health Risk |
Pathogenic |
Encephalopathy, progressive |
| RS766510741 |
GTPBP3
|
Health Risk |
Likely pathogenic |
Combined oxidative phosphorylation defect type 23, Combined oxidative phosphorylation defect type 23 |
| RS766511365 |
CDKL5
|
Health Risk |
Pathogenic |
— |
| RS766511848 |
COQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple system atrophy 1, susceptibility to |
| RS766511916 |
ELP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial dysautonomia, Familial dysautonomia |
| RS766512058 |
SLC35C1
|
Health Risk |
Pathogenic/Likely pathogenic |
Leukocyte adhesion deficiency type II, Leukocyte adhesion deficiency type II |
| RS766512164 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS766512298 |
ALG13
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 36 |
| RS766513025 |
AP4M1
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 50, Hereditary spastic paraplegia 50 |
| RS766515269 |
IRAK4
|
Health Risk |
Pathogenic/Likely pathogenic |
Immunodeficiency 67, Immunodeficiency 67 |
| RS766515318 |
USH2A
|
Health Risk |
Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS766515787 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS766516611 |
NDUFS4
|
Health Risk |
Likely pathogenic |
Mitochondrial complex I deficiency, nuclear type 1 |
| RS766516902 |
DLL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766516963 |
BRIP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS766517126 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS766517983 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS766518199 |
CNNM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Jalili syndrome, Jalili syndrome |
| RS766518430 |
GCDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Glutaric aciduria, type 1 |
| RS766518936 |
RP1
|
Health Risk |
Pathogenic |
— |
| RS766518951 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS766519183 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766520200 |
POP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |