| RS766580479 |
SYNE4
|
Health Risk |
Pathogenic |
Nonsyndromic genetic hearing loss, Nonsyndromic genetic hearing loss |
| RS766580482 |
STAMBP
|
Health Risk |
Pathogenic |
Microcephaly-capillary malformation syndrome, Microcephaly-capillary malformation syndrome |
| RS766580649 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS766581183 |
MRE11
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia-like disorder 1, Ataxia-telangiectasia-like disorder |
| RS766581255 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS766581848 |
PTCHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autism |
| RS766582484 |
HRAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Costello syndrome, Costello syndrome |
| RS766583286 |
SLC9A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital secretory sodium diarrhea 8, Congenital secretory sodium diarrhea 8 |
| RS766583287 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS766583731 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS766583766 |
ADAM9
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Gastric cancer |
| RS766583993 |
ANKRD11
|
Health Risk |
Pathogenic |
KBG syndrome, KBG syndrome |
| RS766584384 |
CPS1
|
Health Risk |
Likely pathogenic |
Congenital hyperammonemia, type I |
| RS766585105 |
NF1
|
Health Risk |
Likely pathogenic |
Neurofibromatosis, type 1 |
| RS766585624 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS766585648 |
CKAP2L
|
Health Risk |
Conflicting classifications of pathogenicity |
Filippi syndrome, Inborn genetic diseases |
| RS766585725 |
SLC12A3
|
Health Risk |
Pathogenic |
— |
| RS766586470 |
TSEN54
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Pontoneocerebellar hypoplasia |
| RS766586765 |
TAP2
|
Health Risk |
Pathogenic |
MHC class I deficiency, MHC class I deficiency |
| RS766587351 |
ATP6V0A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Renal tubular acidosis, distal |
| RS766589204 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS766589324 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Otospondylomegaepiphyseal dysplasia, autosomal recessive |
| RS766589333 |
PNKP
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 12 |
| RS766589514 |
SLC12A5
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 34 |
| RS766589610 |
LRP5
|
Health Risk |
Pathogenic/Likely pathogenic |
6 conditions, 6 conditions |
| RS766590491 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Rare genetic deafness, Retinitis pigmentosa 39 |
| RS766590645 |
ADA
|
Health Risk |
Pathogenic/Likely pathogenic |
Severe combined immunodeficiency, autosomal recessive |
| RS76659072 |
CEP135
|
Health Risk |
Conflicting classifications of pathogenicity |
CEP135-related disorder, CEP135-related disorder |
| RS766591558 |
B4GALNT1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 26, Hereditary spastic paraplegia 26 |
| RS766592492 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS766592611 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
FBN2-related disorder, Familial thoracic aortic aneurysm and aortic dissection |
| RS766592623 |
PHKB
|
Health Risk |
Pathogenic |
Glycogen storage disease IXb, Glycogen storage disease IXb |
| RS766593943 |
DONSON
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766594761 |
GRM6
|
Health Risk |
Pathogenic |
Congenital stationary night blindness 1B, Congenital stationary night blindness 1B |
| RS766595156 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS766595464 |
STRC
|
Health Risk |
Pathogenic |
Rare genetic deafness, Rare genetic deafness |
| RS766598337 |
SETD1A
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, Neurodevelopmental disorder with speech impairment and dysmorphic facies |
| RS766598800 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS766599250 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiomyopathy |
| RS766599883 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS766600036 |
OFD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, Joubert syndrome |
| RS766600687 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS766600801 |
CLPB
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylglutaconic aciduria, type VIIB |
| RS766601503 |
DMP1
|
Health Risk |
Pathogenic |
— |
| RS766601997 |
MCM3AP
|
Health Risk |
Likely pathogenic |
— |
| RS766602053 |
PPOX
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS766602179 |
HPS5
|
Health Risk |
Pathogenic/Likely pathogenic |
Hermansky-Pudlak syndrome 5, Hermansky-Pudlak syndrome |
| RS766602645 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS766602873 |
NBN
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly, normal intelligence and immunodeficiency |
| RS766602945 |
ADA2
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of adenosine deaminase 2, Sneddon syndrome |
| RS766603266 |
NLRP12
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cold autoinflammatory syndrome 2, Familial cold autoinflammatory syndrome 2 |
| RS766603281 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS766603377 |
IDUA
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis type 1, Mucopolysaccharidosis type 1 |
| RS766604570 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS766604600 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS766605124 |
TGM6
|
Health Risk |
Pathogenic |
Spinocerebellar ataxia type 35, Spinocerebellar ataxia type 35 |
| RS766608278 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS766608409 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS766608647 |
KCNQ2
|
Health Risk |
Likely pathogenic |
Early-infantile DEE, Early-infantile DEE |
| RS766608755 |
CEP290
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS766609184 |
ABCA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Interstitial lung disease due to ABCA3 deficiency, Interstitial lung disease due to ABCA3 deficiency |
| RS766609529 |
PCARE
|
Health Risk |
Pathogenic |
— |
| RS766609884 |
DEF6
|
Health Risk |
Pathogenic |
— |
| RS766610061 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS766611189 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS766612482 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS766613420 |
NCF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Granulomatous disease, chronic |
| RS766613810 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, NPHP4-related disorder |
| RS766614772 |
TRAPPC9
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual disability, autosomal recessive 13 |
| RS766614906 |
NOD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Regional enteritis |
| RS766614917 |
BRCA1
|
Health Risk |
Pathogenic |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS766614995 |
PDGFRB
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile myofibromatosis, Acroosteolysis-keloid-like lesions-premature aging syndrome |
| RS766615352 |
GNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-D |
| RS766615729 |
UNC13D
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis 3 |
| RS766616130 |
IL12RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency, Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency |
| RS766616967 |
WDR19
|
Health Risk |
Likely pathogenic |
Asphyxiating thoracic dystrophy 5, Senior-Loken syndrome 8 |
| RS766617434 |
NAXE
|
Health Risk |
Pathogenic |
— |
| RS766617896 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS766618785 |
FANCL
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group L, Fanconi anemia |
| RS766619723 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS766620661 |
BCOR
|
Health Risk |
Pathogenic |
Oculofaciocardiodental syndrome, Oculofaciocardiodental syndrome |
| RS766622060 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 2, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS766622461 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS766623034 |
ATAD3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Harel-Yoon syndrome |
| RS766624923 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS766625084 |
ERI1
|
Health Risk |
Likely pathogenic |
ERI1-associated disorder, Hoxha-Aliu syndrome |
| RS766629205 |
RAB3GAP1
|
Health Risk |
Pathogenic |
Warburg micro syndrome 1, Warburg micro syndrome 1 |
| RS766629618 |
DCAF17
|
Health Risk |
Conflicting classifications of pathogenicity |
Woodhouse-Sakati syndrome, Inborn genetic diseases |
| RS766629924 |
DIS3L2
|
Health Risk |
Pathogenic/Likely pathogenic |
Perlman syndrome, Perlman syndrome |
| RS766629930 |
ERCC6
|
Health Risk |
Pathogenic/Likely pathogenic |
7 conditions, 7 conditions |
| RS766631025 |
POU4F3
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal dominant nonsyndromic hearing loss 15, Autosomal dominant nonsyndromic hearing loss 15 |
| RS766631462 |
RDH12
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis 13, Leber congenital amaurosis |
| RS766632082 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS766632505 |
RAB27A
|
Health Risk |
Pathogenic |
Griscelli syndrome type 2, Griscelli syndrome type 2 |
| RS766632988 |
COL10A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766633448 |
CSPP1
|
Health Risk |
Likely pathogenic |
Joubert syndrome 21, Joubert syndrome 21 |
| RS766633588 |
UIMC1
|
Health Risk |
Likely pathogenic |
— |
| RS766633897 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS766634159 |
KIAA1549
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766635238 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |