IGSF10 Chromosome 3
Immunoglobulin superfamily member 10
Upload your DNA to see your personal genotypes for variants in IGSF10.
What This Gene Does
Predicted to be involved in regulation of neuron migration. Predicted to act upstream of or within ossification. Located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"I-set domain containing|MicroRNA protein coding host genes"
Locus Type
gene with protein product
Location
3q25.1
Ensembl
ENSG00000152580
Associated Conditions (2)
IGSF10-related disorder
Premature ovarian failure
Key Variants
RS140012391
Conflicting classifications of pathogenicity
Health Risk
RS140241435
Conflicting classifications of pathogenicity
Health Risk
RS144521359
Conflicting classifications of pathogenicity
Health Risk
RS149685136
Conflicting classifications of pathogenicity
Health Risk
RS150329686
Conflicting classifications of pathogenicity
IGSF10-related disorder, IGSF10-related disorder
Health Risk
RS200898424
Conflicting classifications of pathogenicity
Health Risk
RS201186884
Conflicting classifications of pathogenicity
Health Risk
RS35667704
Conflicting classifications of pathogenicity
Premature ovarian failure, IGSF10-related disorder, Premature ovarian failure
Health Risk
RS370165815
Conflicting classifications of pathogenicity
Health Risk
RS374160587
Conflicting classifications of pathogenicity
Health Risk
RS767429459
Conflicting classifications of pathogenicity
Health Risk
RS774302298
Conflicting classifications of pathogenicity
Health Risk
All Variants (13)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS140012391 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS140241435 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS144521359 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS149685136 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS150329686 | Health Risk | Conflicting classifications of pathogenicity | IGSF10-related disorder, IGSF10-related disorder |
| RS200898424 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS201186884 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS35667704 | Health Risk | Conflicting classifications of pathogenicity | Premature ovarian failure, IGSF10-related disorder, Premature ovarian failure |
| RS370165815 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS374160587 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS767429459 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS774302298 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS781609575 | Health Risk | Conflicting classifications of pathogenicity | — |