| RS766166913 |
LAMA2
|
Health Risk |
Pathogenic |
Merosin deficient congenital muscular dystrophy, Merosin deficient congenital muscular dystrophy |
| RS766167046 |
PDZD7
|
Health Risk |
Pathogenic |
Usher syndrome, Usher syndrome |
| RS766167375 |
KIAA0825
|
Health Risk |
Pathogenic |
Polydactyly, postaxial |
| RS766168524 |
GNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-D |
| RS766168647 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Polymerase proofreading-related adenomatous polyposis |
| RS766168717 |
EMC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cerebellar atrophy, visual impairment |
| RS766168868 |
NEB
|
Health Risk |
Pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS766169193 |
POMT2
|
Health Risk |
Pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A2 |
| RS766169253 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS766169444 |
WFS1
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Wolfram syndrome 1, Inborn genetic diseases |
| RS766170422 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS766172626 |
NEXMIF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766173 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS766173546 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 2, Hereditary cancer-predisposing syndrome |
| RS766173642 |
ACADM
|
Health Risk |
Likely pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS766173950 |
TTLL5
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS766175179 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS766175657 |
SOX10
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766177007 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS766177957 |
LAMB3
|
Health Risk |
Likely pathogenic |
Junctional epidermolysis bullosa, Junctional epidermolysis bullosa |
| RS766178353 |
NPC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Niemann-Pick disease, type C1 |
| RS766178412 |
TCIRG1
|
Health Risk |
Pathogenic |
— |
| RS766179352 |
MBD5
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal dominant 1 |
| RS766181526 |
TULP1
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Leber congenital amaurosis |
| RS766181895 |
MAP3K7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766183395 |
ACADS
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of butyryl-CoA dehydrogenase, Deficiency of butyryl-CoA dehydrogenase |
| RS766184155 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS766184697 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sotos syndrome, Sotos syndrome |
| RS766184763 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766187198 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 11 |
| RS766187468 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS766187894 |
PACS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766187994 |
MYO15A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, MYO15A-related disorder |
| RS766188849 |
PNPLA1
|
Health Risk |
Likely pathogenic |
Congenital ichthyosiform erythroderma, Lamellar ichthyosis |
| RS766188851 |
OCA2
|
Health Risk |
Pathogenic |
SKIN/HAIR/EYE PIGMENTATION 1, BLUE/NONBLUE EYES |
| RS766190197 |
ADGRV1
|
Health Risk |
Likely pathogenic |
— |
| RS766191360 |
SLC6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Parkinsonism-dystonia, infantile |
| RS766191969 |
HNF1A
|
Health Risk |
Pathogenic |
Maturity-onset diabetes of the young type 3, Type 1 diabetes mellitus 20 |
| RS766192644 |
GIPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766192888 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS766193278 |
NEFH
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease axonal type 2CC, Charcot-Marie-Tooth disease axonal type 2CC |
| RS766194658 |
CEP152
|
Health Risk |
Likely pathogenic |
Seckel syndrome 5, Microcephaly 9 |
| RS766195581 |
ASXL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766196208 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS766196255 |
TARDBP
|
Health Risk |
Pathogenic |
Amyotrophic lateral sclerosis type 10, FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS |
| RS766196673 |
CYP2U1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Spastic paraplegia |
| RS766196697 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy |
| RS766196737 |
RHO
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 4, Retinitis pigmentosa 4 |
| RS766196837 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS766197164 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS766197882 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS766198119 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS766198135 |
STXBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 5, Autoinflammatory syndrome |
| RS766198611 |
SLC3A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cystinuria, Cystinuria |
| RS766199191 |
PYGM
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease, type V |
| RS766199335 |
CDC20
|
Health Risk |
Pathogenic |
Oocyte maturation defect 14, Oocyte maturation defect 14 |
| RS766199339 |
NKX2-5
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial septal defect 7, Cardiovascular phenotype |
| RS766199971 |
HSD17B4
|
Health Risk |
Pathogenic/Likely pathogenic |
Bifunctional peroxisomal enzyme deficiency, Perrault syndrome 1 |
| RS766200310 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS766200402 |
TTPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial isolated deficiency of vitamin E, Familial isolated deficiency of vitamin E |
| RS766200637 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial meningioma, Hereditary cancer-predisposing syndrome |
| RS766202031 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS766202221 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS766203252 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome 2, Long QT syndrome |
| RS766203266 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 9, Meckel syndrome |
| RS766203500 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS766204229 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS766204907 |
SCN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 5, Cardiovascular phenotype |
| RS766205107 |
PCNT
|
Health Risk |
Pathogenic/Likely pathogenic |
PCNT-related disorder, Microcephalic osteodysplastic primordial dwarfism type II |
| RS766205731 |
SHANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766206507 |
SLC26A4
|
Health Risk |
Pathogenic |
Pendred syndrome, Autosomal recessive nonsyndromic hearing loss 4 |
| RS766207096 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS766208466 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Hematuria |
| RS766209297 |
PKP2
|
Health Risk |
Pathogenic/Likely pathogenic |
Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia 9 |
| RS766209304 |
SGCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Autosomal recessive limb-girdle muscular dystrophy type 2D |
| RS766209790 |
CPT1A
|
Health Risk |
Likely pathogenic |
Carnitine palmitoyl transferase 1A deficiency, Carnitine palmitoyl transferase 1A deficiency |
| RS766209938 |
COL4A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Abnormal cerebral cortex morphology, Corpus callosum |
| RS766211091 |
SMO
|
Health Risk |
Likely pathogenic |
Congenital hypothalamic hamartoma syndrome, Congenital hypothalamic hamartoma syndrome |
| RS766211536 |
COL11A2
|
Health Risk |
Pathogenic |
— |
| RS766212625 |
FOXRED1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766212849 |
SCN9A
|
Health Risk |
Pathogenic |
Generalized epilepsy with febrile seizures plus, type 7 |
| RS766213678 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS766214390 |
CTC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Dyskeratosis congenita, Cerebroretinal microangiopathy with calcifications and cysts 1 |
| RS766215027 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766215295 |
AGBL5
|
Health Risk |
Likely pathogenic |
— |
| RS766215523 |
PNPLA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive congenital ichthyosis 10, Autosomal recessive congenital ichthyosis 10 |
| RS766216871 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, MYH7-related skeletal myopathy |
| RS766217603 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS766218250 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Birt-Hogg-Dube syndrome |
| RS766218865 |
BBS1
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome |
| RS766219320 |
MMUT
|
Health Risk |
Pathogenic |
— |
| RS766220173 |
LOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS766220211 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766221834 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group O |
| RS766222251 |
ENTPD1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 64, Hereditary spastic paraplegia 64 |
| RS766223343 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS766223757 |
CEP152
|
Health Risk |
Conflicting classifications of pathogenicity |
Seckel syndrome 5, Microcephaly 9 |
| RS766223850 |
TTR
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766225545 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2, Usher syndrome type 2 |
| RS766226888 |
CNOT3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |