| RS766044536 |
SLC25A13
|
Health Risk |
Likely pathogenic |
Citrullinemia, type II |
| RS766044564 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Brugada syndrome |
| RS766044613 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Medulloblastoma |
| RS766044684 |
NBN
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS766044749 |
DST
|
Health Risk |
Pathogenic |
Hereditary sensory and autonomic neuropathy type 6, Epidermolysis bullosa simplex 3 |
| RS766045217 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebral arteriopathy, autosomal dominant |
| RS766045910 |
MCCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylcrotonyl-CoA carboxylase 2 deficiency, 3-methylcrotonyl-CoA carboxylase 2 deficiency |
| RS766046008 |
INPP5K
|
Health Risk |
Pathogenic |
Congenital muscular dystrophy with cataracts and intellectual disability, Congenital muscular dystrophy with cataracts and intellectual disability |
| RS766046177 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS766047812 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS766049052 |
ASXL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766049739 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS766050153 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS766051225 |
DNMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory neuropathy-deafness-dementia syndrome, Autosomal dominant cerebellar ataxia |
| RS766051613 |
RAPSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Fetal akinesia deformation sequence 1, Congenital myasthenic syndrome 11 |
| RS766053182 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS766053734 |
FGFR3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766053952 |
DHX38
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 84, Autosomal recessive retinitis pigmentosa |
| RS766054125 |
CHCHD10
|
Health Risk |
Conflicting classifications of pathogenicity |
Lower motor neuron syndrome with late-adult onset, Frontotemporal dementia and/or amyotrophic lateral sclerosis 2 |
| RS766054897 |
RAB28
|
Health Risk |
Likely pathogenic |
— |
| RS766055241 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperkalemic periodic paralysis, 7 conditions |
| RS766055427 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766055577 |
GNPTG
|
Health Risk |
Pathogenic |
— |
| RS766055659 |
PI4K2A
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with hyperkinetic movements, seizures |
| RS766056004 |
WDPCP
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome, WDPCP-related disorder |
| RS766057861 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Duchenne muscular dystrophy |
| RS766058276 |
ROR2
|
Health Risk |
Pathogenic |
— |
| RS766058636 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group O, Breast-ovarian cancer |
| RS766058852 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS766061024 |
BSCL2
|
Health Risk |
Pathogenic |
Congenital generalized lipodystrophy type 2, Berardinelli-Seip congenital lipodystrophy |
| RS766061901 |
CARD9
|
Health Risk |
Pathogenic |
Predisposition to invasive fungal disease due to CARD9 deficiency, Predisposition to invasive fungal disease due to CARD9 deficiency |
| RS766062562 |
LIPA
|
Health Risk |
Likely pathogenic |
Lysosomal acid lipase deficiency, Lysosomal acid lipase deficiency |
| RS766063111 |
RIT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 8, Cardiovascular phenotype |
| RS766063253 |
CTSC
|
Health Risk |
Conflicting classifications of pathogenicity |
Haim-Munk syndrome, Papillon-Lefèvre syndrome |
| RS766063304 |
CFTR
|
Health Risk |
Pathogenic/Likely pathogenic |
Cystic fibrosis, CFTR-related disorder |
| RS766066977 |
ETFB
|
Health Risk |
Likely pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS766067138 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS766068851 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Diabetes mellitus, permanent neonatal 3 |
| RS766069252 |
SRRM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766069291 |
AHI1
|
Health Risk |
Pathogenic |
Nephronophthisis, Joubert syndrome |
| RS766072117 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS766072141 |
OCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tyrosinase-positive oculocutaneous albinism, Tyrosinase-positive oculocutaneous albinism |
| RS766073664 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome 5 |
| RS766073729 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS766074604 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS766074609 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS766075840 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Duchenne muscular dystrophy |
| RS766076524 |
SLC9A3
|
Health Risk |
Pathogenic |
Congenital secretory sodium diarrhea 8, Congenital secretory sodium diarrhea 8 |
| RS766076722 |
CHRNA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS766076920 |
ALPL
|
Health Risk |
Pathogenic |
Infantile hypophosphatasia, Hypophosphatasia |
| RS766078852 |
EPHA2
|
Health Risk |
Likely pathogenic |
Cataract 6 multiple types, Cataract 6 multiple types |
| RS766079334 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766080044 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS766080208 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS766080221 |
HPS1
|
Health Risk |
Likely pathogenic |
Hermansky-Pudlak syndrome 1, Hermansky-Pudlak syndrome 1 |
| RS766080270 |
IL12RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency, Inborn genetic diseases |
| RS766080403 |
C8B
|
Health Risk |
Likely pathogenic |
Cholangiocarcinoma, Cholangiocarcinoma |
| RS766081510 |
SLX4
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS766083746 |
PIGG
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal recessive 53 |
| RS766084603 |
IFT140
|
Health Risk |
Pathogenic/Likely pathogenic |
Saldino-Mainzer syndrome, Retinitis pigmentosa 80 |
| RS766085073 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, Tip-toe gait |
| RS766085522 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Alport syndrome, Inborn genetic diseases |
| RS766086010 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, APC-Associated Polyposis Disorders |
| RS766086120 |
FANCC
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Hereditary cancer-predisposing syndrome |
| RS766086210 |
FANCG
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group G, Ovarian cancer |
| RS766086544 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, Rubinstein-Taybi syndrome |
| RS766086682 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS766087007 |
TRIT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation deficiency 35, Combined oxidative phosphorylation deficiency 35 |
| RS766087213 |
CFAP418
|
Health Risk |
Pathogenic |
Bardet-biedl syndrome 21, Bardet-biedl syndrome 21 |
| RS766088687 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766088717 |
PDE6B
|
Health Risk |
Likely pathogenic |
— |
| RS766089213 |
SKIC2
|
Health Risk |
Pathogenic |
— |
| RS766090540 |
SZT2
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 18 |
| RS766091136 |
DYSF
|
Health Risk |
Pathogenic/Likely pathogenic |
Miyoshi muscular dystrophy 1, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS766093573 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS766093661 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS766094434 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS766095051 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Early-onset myopathy with fatal cardiomyopathy |
| RS766095612 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Tip-toe gait, Menke-Hennekam syndrome 1 |
| RS766095901 |
CEP290
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome 14, Nephronophthisis |
| RS766096320 |
WDR35
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 7 with or without polydactyly, Cranioectodermal dysplasia 2 |
| RS766096417 |
NR2E3
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa |
| RS766097440 |
HMGCS2
|
Health Risk |
Conflicting classifications of pathogenicity |
3-hydroxy-3-methylglutaryl-CoA synthase deficiency, 3-hydroxy-3-methylglutaryl-CoA synthase deficiency |
| RS766097494 |
AHNAK2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766098800 |
GATA3
|
Health Risk |
Pathogenic |
Hypoparathyroidism, deafness |
| RS766098919 |
BBS2
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome 1, Bardet-Biedl syndrome 1 |
| RS766099303 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS766100418 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS766102187 |
IRAK4
|
Health Risk |
Pathogenic |
Immunodeficiency 67, Immunodeficiency 67 |
| RS766102716 |
ERBB3
|
Health Risk |
Pathogenic |
Visceral neuropathy, familial |
| RS766102981 |
EIF2B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Vanishing white matter disease, Vanishing white matter disease |
| RS766104513 |
SAG
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa, Oguchi disease |
| RS766104579 |
PEX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, Peroxisome biogenesis disorder |
| RS766104877 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS766105286 |
FANCC
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group C |
| RS766106194 |
BRAT1
|
Health Risk |
Likely pathogenic |
Neonatal-onset encephalopathy with rigidity and seizures, Neonatal-onset encephalopathy with rigidity and seizures |
| RS766106312 |
OPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant optic atrophy classic form, Autosomal dominant optic atrophy classic form |
| RS766106686 |
ITGB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukocyte adhesion deficiency 1, Leukocyte adhesion deficiency 1 |
| RS766106748 |
CLCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766106805 |
FAM20C
|
Health Risk |
Conflicting classifications of pathogenicity |
— |