| RS765923395 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Hematuria |
| RS765924360 |
GNPTAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS765924757 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS765925466 |
NLRP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cryopyrin associated periodic syndrome, Chronic infantile neurological |
| RS765926045 |
WASHC5
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 8, Ritscher-Schinzel syndrome |
| RS765926181 |
PAX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Irido-corneo-trabecular dysgenesis, Aniridia 1 |
| RS765926471 |
IBA57
|
Health Risk |
Pathogenic |
Multiple mitochondrial dysfunctions syndrome 3, Hereditary spastic paraplegia 74 |
| RS765927456 |
CYP11B2
|
Health Risk |
Pathogenic |
— |
| RS765927570 |
G6PC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency, Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency |
| RS765928741 |
SERPINF1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765928877 |
PGAP3
|
Health Risk |
Likely pathogenic |
Hyperphosphatasia-intellectual disability syndrome, Hyperphosphatasia-intellectual disability syndrome |
| RS765929402 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Adams-Oliver syndrome 5 |
| RS765929630 |
CDH1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cancer of breast, Hereditary diffuse gastric adenocarcinoma |
| RS765929647 |
MYO6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 37, Autosomal dominant nonsyndromic hearing loss 22 |
| RS765930349 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765931465 |
MYPN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1KK, Cardiovascular phenotype |
| RS765931769 |
EPHB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS765933558 |
KNG1
|
Health Risk |
Pathogenic |
Angioedema, hereditary |
| RS765934021 |
PKHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS765934383 |
FKTN
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A |
| RS765934604 |
PAH
|
Health Risk |
Likely pathogenic |
Phenylketonuria, Phenylketonuria |
| RS765934820 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
MYO15A-related disorder, MYO15A-related disorder |
| RS765935351 |
CAPN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy |
| RS765936799 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemiplegic migraine, Fetal akinesia |
| RS765937590 |
TMPRSS15
|
Health Risk |
Pathogenic/Likely pathogenic |
Enterokinase deficiency, Enterokinase deficiency |
| RS765938298 |
CEP120
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 13 with or without polydactyly, Inborn genetic diseases |
| RS765938367 |
ABCG8
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS76593842 |
WHRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2D, Autosomal recessive nonsyndromic hearing loss 31 |
| RS765939287 |
SLC26A4
|
Health Risk |
Likely pathogenic |
Pendred syndrome, Pendred syndrome |
| RS765940770 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS765941217 |
SPAST
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 4, Hereditary spastic paraplegia 4 |
| RS765941470 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS765941497 |
HAX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kostmann syndrome, Inborn genetic diseases |
| RS765941616 |
CUBN
|
Health Risk |
Pathogenic |
Imerslund-Grasbeck syndrome, Imerslund-Grasbeck syndrome |
| RS765942432 |
FBN1
|
Health Risk |
Pathogenic |
Marfan Syndrome/Loeys-Dietz Syndrome/Familial Thoracic Aortic Aneurysms and Dissections, Familial thoracic aortic aneurysm and aortic dissection |
| RS765942523 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS765943080 |
NSUN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation deficiency 48, Combined oxidative phosphorylation deficiency 48 |
| RS765943112 |
LAMA3
|
Health Risk |
Pathogenic |
— |
| RS765943218 |
TRAPPC9
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal recessive 13 |
| RS765943226 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS765944082 |
LOXHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765948222 |
ITK
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Lymphoproliferative syndrome 1 |
| RS765950547 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Dystrophin deficiency |
| RS765950779 |
KAT6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765951750 |
AP4E1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS765951860 |
TECTA
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765952535 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, Osteogenesis imperfecta |
| RS765952713 |
ADCY5
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskinesia with orofacial involvement, autosomal recessive |
| RS765953819 |
RRM2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 5 |
| RS765954398 |
SLC22A5
|
Health Risk |
Likely pathogenic |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS765955245 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, CREBBP-related disorder |
| RS765956155 |
CFI
|
Health Risk |
Conflicting classifications of pathogenicity |
CFI-related disorder, CFI-related disorder |
| RS765956720 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS765956865 |
LRSAM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2P, Inborn genetic diseases |
| RS765957120 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS765957571 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS765957925 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS765958123 |
VCAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765958312 |
DNAH11
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765960304 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Congenital muscular dystrophy due to partial LAMA2 deficiency |
| RS765960386 |
MMACHC
|
Health Risk |
Pathogenic |
Cobalamin C disease, Cobalamin C disease |
| RS765961551 |
ACAT1
|
Health Risk |
Likely pathogenic |
Deficiency of acetyl-CoA acetyltransferase, Deficiency of acetyl-CoA acetyltransferase |
| RS765962519 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, Cardiovascular phenotype |
| RS765965513 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS765965968 |
TBC1D24
|
Health Risk |
Likely pathogenic |
Epilepsy, progressive myoclonic |
| RS765966679 |
COQ8A
|
Health Risk |
Likely pathogenic |
Autosomal recessive ataxia due to ubiquinone deficiency, Autosomal recessive ataxia due to ubiquinone deficiency |
| RS765967405 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Hereditary spastic paraplegia |
| RS765968701 |
STAR
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital lipoid adrenal hyperplasia due to STAR deficency, STAR-related disorder |
| RS765968784 |
PIGO
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperphosphatasia with intellectual disability syndrome 2, Hyperphosphatasia with intellectual disability syndrome 2 |
| RS765969481 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS765969571 |
GUSB
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis type 7, Mucopolysaccharidosis type 7 |
| RS765970053 |
FAN1
|
Health Risk |
Pathogenic |
Karyomegalic interstitial nephritis, Karyomegalic interstitial nephritis |
| RS765970420 |
CYB5R3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765970732 |
SPTLC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory and autonomic neuropathy type 1, Inborn genetic diseases |
| RS765971817 |
TMEM127
|
Health Risk |
Conflicting classifications of pathogenicity |
Pheochromocytoma, Hereditary pheochromocytoma and paraganglioma |
| RS765974121 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS765974570 |
PEPD
|
Health Risk |
Conflicting classifications of pathogenicity |
Prolidase deficiency, Inborn genetic diseases |
| RS765975578 |
GTPBP3
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined oxidative phosphorylation defect type 23, GTPBP3-related disorder |
| RS765975804 |
TJP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholanemia, familial 1 |
| RS765975825 |
RAD50
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Nijmegen breakage syndrome-like disorder |
| RS765975898 |
CHIT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Chitotriosidase deficiency, Chitotriosidase deficiency |
| RS765976119 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS765976563 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Genitopatellar syndrome, Blepharophimosis - intellectual disability syndrome |
| RS765977046 |
ADGRV1
|
Health Risk |
Likely pathogenic |
— |
| RS765977497 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS765978945 |
VHL
|
Health Risk |
Pathogenic |
Von Hippel-Lindau syndrome, Hereditary cancer-predisposing syndrome |
| RS765979499 |
RPGR
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS765979836 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765980788 |
DNAH5
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS765981100 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS765981178 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS765981944 |
PARN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal recessive 6 |
| RS765982075 |
WASHC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Ritscher-Schinzel syndrome, Hereditary spastic paraplegia 8 |
| RS765982317 |
GPR50
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS765982831 |
SOX2
|
Health Risk |
Likely pathogenic |
— |
| RS765982916 |
F5
|
Health Risk |
Pathogenic/Likely pathogenic |
Factor V deficiency, Congenital factor V deficiency |
| RS765983264 |
TRIM37
|
Health Risk |
Conflicting classifications of pathogenicity |
Mulibrey nanism syndrome, Mulibrey nanism syndrome |
| RS765984252 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS765985758 |
AHI1
|
Health Risk |
Pathogenic |
Joubert syndrome, Joubert syndrome |
| RS765985953 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |