| RS766227083 |
LAMB3
|
Health Risk |
Likely pathogenic |
Junctional epidermolysis bullosa gravis of Herlitz, Junctional epidermolysis bullosa gravis of Herlitz |
| RS766227557 |
PTCH1
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS766228902 |
RFWD3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766229168 |
TCF20
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766229978 |
OTOG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766231298 |
MLC1
|
Health Risk |
Likely pathogenic |
Megalencephalic leukoencephalopathy with subcortical cysts, Megalencephalic leukoencephalopathy with subcortical cysts |
| RS766232161 |
SLC1A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome, Spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome |
| RS766232837 |
GALNT3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766232933 |
NR2E3
|
Health Risk |
Pathogenic/Likely pathogenic |
Enhanced S-cone syndrome, Retinitis pigmentosa 37 |
| RS766234016 |
GFM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1, Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1 |
| RS766234350 |
HESX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Septo-optic dysplasia sequence |
| RS766234642 |
AGL
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease type III, Inborn genetic diseases |
| RS766235917 |
SZT2
|
Health Risk |
Pathogenic |
— |
| RS766236522 |
HOGA1
|
Health Risk |
Likely pathogenic |
Primary hyperoxaluria type 3, Primary hyperoxaluria type 3 |
| RS766237791 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS766238385 |
ZSWIM6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766239144 |
ABCA4
|
Health Risk |
Pathogenic/Likely pathogenic |
Severe early-childhood-onset retinal dystrophy, Severe early-childhood-onset retinal dystrophy |
| RS766239881 |
PNKP
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 12 |
| RS766240294 |
POMT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B1 |
| RS766240417 |
PCCB
|
Health Risk |
Likely pathogenic |
Propionic acidemia, Propionic acidemia |
| RS766240657 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766241071 |
LAMA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa gravis of Herlitz, Laryngo-onycho-cutaneous syndrome |
| RS766241260 |
PKD1
|
Health Risk |
Pathogenic |
PKD1-related disorder, PKD1-related disorder |
| RS766241881 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Dilated cardiomyopathy 1G |
| RS766242199 |
PC
|
Health Risk |
Pathogenic/Likely pathogenic |
Pyruvate carboxylase deficiency, Thrombophilia due to protein C deficiency |
| RS766243664 |
COL4A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive Alport syndrome, Alport syndrome |
| RS766243954 |
APOB
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS766244312 |
COG8
|
Health Risk |
Likely pathogenic |
COG8-congenital disorder of glycosylation, COG8-related disorder |
| RS766244944 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766246531 |
PROM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 41, Retinal dystrophy |
| RS766249735 |
ACADM
|
Health Risk |
Likely pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, MCADD - Medium-chain acyl-CoA dehydrogenase deficiency – full ACADM sequencing newborn screening follow up |
| RS766249962 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, CHARGE syndrome |
| RS766250454 |
MYO15A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS766250601 |
AEBP1
|
Health Risk |
Likely pathogenic |
— |
| RS766250689 |
KCNJ16
|
Health Risk |
Likely pathogenic |
Hypokalemic tubulopathy and deafness, Hypokalemic tubulopathy and deafness |
| RS766251338 |
AARS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease type 2, Colon adenocarcinoma |
| RS766251466 |
PANK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pigmentary pallidal degeneration, Pigmentary pallidal degeneration |
| RS766251541 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS766254024 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS766254214 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS766256094 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 5, Cerebrooculofacioskeletal syndrome 1 |
| RS766256171 |
TERB1
|
Health Risk |
Pathogenic |
Azoospermia, Azoospermia |
| RS766256391 |
DNAH8
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS766256429 |
NPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Short stature with nonspecific skeletal abnormalities, Acromesomelic dysplasia 1 |
| RS766257849 |
LAMA2
|
Health Risk |
Pathogenic |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS766257867 |
ASAH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinal muscular atrophy-progressive myoclonic epilepsy syndrome, Spinal muscular atrophy-progressive myoclonic epilepsy syndrome |
| RS766258051 |
SCN3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766259648 |
CEP290
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Nephronophthisis |
| RS76625999 |
SMC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cornelia de Lange syndrome 3, Inborn genetic diseases |
| RS766261022 |
PROC
|
Health Risk |
Likely pathogenic |
Thrombophilia due to protein C deficiency, autosomal dominant |
| RS766264473 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS76626460 |
DIAPH3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766264810 |
ALDH18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 9A, Cutis laxa |
| RS766265410 |
CEP290
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Nephronophthisis |
| RS766265889 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Cardiomyopathy |
| RS766266851 |
CARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation defect type 27, Combined oxidative phosphorylation defect type 27 |
| RS766266918 |
GNE
|
Health Risk |
Conflicting classifications of pathogenicity |
Sialuria, GNE myopathy |
| RS766270336 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary cancer-predisposing syndrome |
| RS766270982 |
SMAD6
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic valve disease 2, Aortic valve disease 2 |
| RS766271753 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS766273160 |
TRMT5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766273161 |
ROBO2
|
Health Risk |
Conflicting classifications of pathogenicity |
Vesicoureteral reflux 2, Inborn genetic diseases |
| RS766273613 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS766274915 |
IFT122
|
Health Risk |
Conflicting classifications of pathogenicity |
Cranioectodermal dysplasia 1, Cranioectodermal dysplasia 1 |
| RS766274999 |
B3GALT6
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, spondylodysplastic type |
| RS766275230 |
DYNC2H1
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Asphyxiating thoracic dystrophy 3 |
| RS766277488 |
SBDS
|
Health Risk |
Conflicting classifications of pathogenicity |
Shwachman-Diamond syndrome 1, Shwachman-Diamond syndrome 1 |
| RS766278192 |
NPHS1
|
Health Risk |
Pathogenic |
Finnish congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS766278489 |
RLBP1
|
Health Risk |
Pathogenic |
Newfoundland cone-rod dystrophy, Retinitis punctata albescens |
| RS766279277 |
CPAMD8
|
Health Risk |
Pathogenic |
— |
| RS766279442 |
FANCF
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group F, Fanconi anemia complementation group F |
| RS766279840 |
DOCK6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS766279884 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS766279892 |
LRAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 14, Leber congenital amaurosis 14 |
| RS766280701 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Episodic pain syndrome |
| RS766282869 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS766282946 |
TMEM67
|
Health Risk |
Likely pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS766283832 |
COX15
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardioencephalomyopathy, fatal infantile |
| RS766284226 |
FZD6
|
Health Risk |
Pathogenic |
Nonsyndromic congenital nail disorder 1, Nonsyndromic congenital nail disorder 1 |
| RS766285158 |
ABCB11
|
Health Risk |
Likely pathogenic |
Familial intrahepatic cholestasis type 2, Progressive familial intrahepatic cholestasis type 2 |
| RS766285443 |
CEP290
|
Health Risk |
Pathogenic/Likely pathogenic |
CEP290-related disorder, Joubert syndrome 5 |
| RS766285779 |
NPHP3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS766286119 |
DLD
|
Health Risk |
Conflicting classifications of pathogenicity |
Leigh syndrome, Pyruvate dehydrogenase complex deficiency |
| RS766286901 |
ABCB11
|
Health Risk |
Likely pathogenic |
Progressive familial intrahepatic cholestasis type 2, Progressive familial intrahepatic cholestasis type 2 |
| RS766287925 |
ALDH7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyridoxine-dependent epilepsy, Pyridoxine-dependent epilepsy |
| RS766288440 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS766288973 |
TXNRD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Primary dilated cardiomyopathy |
| RS766289147 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, PIEZO1-related disorder |
| RS766291321 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS766291662 |
SMARCAL1
|
Health Risk |
Pathogenic |
Schimke immuno-osseous dysplasia, Schimke immuno-osseous dysplasia |
| RS766292710 |
CLN8
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 8, Neuronal ceroid lipofuscinosis |
| RS766294940 |
RNASEH1
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2 |
| RS766294997 |
F7
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS766295044 |
JPH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiovascular phenotype |
| RS766296358 |
LAMA2
|
Health Risk |
Likely pathogenic |
Merosin deficient congenital muscular dystrophy, Muscular dystrophy |
| RS766297596 |
PTPN11
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Noonan syndrome 1 |
| RS766297775 |
LMNB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lipodystrophy, partial |
| RS766298096 |
SUMF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple sulfatase deficiency, Multiple sulfatase deficiency |
| RS766298777 |
BMPR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Juvenile polyposis syndrome |
| RS766298888 |
GMPPB
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2T, Autosomal recessive limb-girdle muscular dystrophy type 2T |