| RS749464836 |
CDAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital dyserythropoietic anemia, type I |
| RS749464972 |
WDPCP
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome |
| RS749465060 |
MITF
|
Health Risk |
Conflicting classifications of pathogenicity |
Tietz syndrome, Waardenburg syndrome type 2A |
| RS749465098 |
MYO15A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS749465132 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS749465164 |
ALPK3
|
Health Risk |
Pathogenic |
Cardiomyopathy, familial hypertrophic 27 |
| RS749465732 |
ARSB
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis type 6, Mucopolysaccharidosis type 6 |
| RS749466673 |
RAD50
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Nijmegen breakage syndrome-like disorder |
| RS749468605 |
AQP2
|
Health Risk |
Likely pathogenic |
Diabetes insipidus, nephrogenic |
| RS749468712 |
KANK1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749469486 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS749469874 |
EIF2B5
|
Health Risk |
Likely pathogenic |
Vanishing white matter disease, Vanishing white matter disease |
| RS749471277 |
GPR179
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital stationary night blindness 1E, Congenital stationary night blindness 1E |
| RS749471737 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS749472361 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, ATP7B-related disorder |
| RS749472520 |
MERTK
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS749473441 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS749473632 |
CPLANE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 17, Joubert syndrome 17 |
| RS749474186 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS749474432 |
ACAD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of isobutyryl-CoA dehydrogenase, Inborn genetic diseases |
| RS749475908 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
KMT2D-related disorder, Kabuki syndrome |
| RS749475936 |
KIAA0586
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome 23, Short-rib thoracic dysplasia 14 with polydactyly |
| RS749476176 |
PIGG
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal recessive 53 |
| RS749476593 |
MOGS
|
Health Risk |
Pathogenic |
MOGS-congenital disorder of glycosylation, MOGS-congenital disorder of glycosylation |
| RS749477738 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS749478956 |
WASHC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 8, Ritscher-Schinzel syndrome |
| RS749479682 |
APC
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS749479992 |
NEXMIF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749480979 |
CARD14
|
Health Risk |
Conflicting classifications of pathogenicity |
Psoriasis 2, Pityriasis rubra pilaris |
| RS749481247 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749481321 |
TCTN1
|
Health Risk |
Likely pathogenic |
Joubert syndrome and related disorders, Joubert syndrome and related disorders |
| RS749481781 |
JAK3
|
Health Risk |
Pathogenic/Likely pathogenic |
T-B+ severe combined immunodeficiency due to JAK3 deficiency, T-B+ severe combined immunodeficiency due to JAK3 deficiency |
| RS749483911 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Alport syndrome, Inborn genetic diseases |
| RS749484350 |
SPAST
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 4, Hereditary spastic paraplegia 4 |
| RS749484470 |
ALG5
|
Health Risk |
Pathogenic |
Polycystic kidney disease 7, Gastric cancer |
| RS749484478 |
SERPING1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749484691 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS749484894 |
ADA
|
Health Risk |
Pathogenic |
Severe combined immunodeficiency, autosomal recessive |
| RS749484938 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS749485360 |
BMP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type 13, Osteogenesis imperfecta type 13 |
| RS749485755 |
BMPR2
|
Health Risk |
Pathogenic |
Pulmonary arterial hypertension, Pulmonary arterial hypertension |
| RS749485884 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS749486726 |
TPO
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of iodide peroxidase, Deficiency of iodide peroxidase |
| RS749487037 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS749487379 |
BCKDHA
|
Health Risk |
Pathogenic |
Maple syrup urine disease, Maple syrup urine disease |
| RS749487441 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS749488054 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS749488943 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749489444 |
CD46
|
Health Risk |
Pathogenic |
— |
| RS749490263 |
MTHFR
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual disability, Homocystinuria due to methylene tetrahydrofolate reductase deficiency |
| RS749490844 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS749491616 |
ACADS
|
Health Risk |
Pathogenic |
Deficiency of butyryl-CoA dehydrogenase, Deficiency of butyryl-CoA dehydrogenase |
| RS749491943 |
TMC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Rare genetic deafness, Autosomal recessive nonsyndromic hearing loss 7 |
| RS749494588 |
IL6R
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749494645 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group N |
| RS749494995 |
ASH1L
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal dominant 52 |
| RS749495580 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS749495615 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, Inborn genetic diseases |
| RS749495704 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS749496136 |
LMNB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lipodystrophy, partial |
| RS749496192 |
LAMC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, Inborn genetic diseases |
| RS749496245 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS749496657 |
RTEL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal recessive 5 |
| RS749497185 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS749497447 |
CCDC39
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 14 |
| RS749497678 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749498958 |
SMG9
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with intention tremor, pyramidal signs |
| RS749499150 |
SLC39A13
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, spondylocheirodysplastic type |
| RS749499293 |
SLC22A5
|
Health Risk |
Likely pathogenic |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS749499960 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS749500174 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS749501410 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS749503755 |
EPHB4
|
Health Risk |
Pathogenic |
Capillary malformation-arteriovenous malformation 2, Capillary malformation-arteriovenous malformation 2 |
| RS749503841 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS749504112 |
COQ4
|
Health Risk |
Pathogenic |
Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndrome, Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndrome |
| RS749504196 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Alstrom syndrome |
| RS749506103 |
MED17
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749507212 |
OTOA
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749508254 |
BRCA1
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS749508276 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS749508862 |
TRMU
|
Health Risk |
Likely pathogenic |
Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins, Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins |
| RS749508948 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749509242 |
TYRP1
|
Health Risk |
Pathogenic |
— |
| RS749509412 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS749509618 |
PCCB
|
Health Risk |
Pathogenic/Likely pathogenic |
Propionic acidemia, PCCB-related disorder |
| RS749509661 |
CUL7
|
Health Risk |
Pathogenic |
Inborn genetic diseases, 3M syndrome 1 |
| RS749509886 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 43 |
| RS749511015 |
KCNQ3
|
Health Risk |
Conflicting classifications of pathogenicity |
Seizures, benign familial neonatal |
| RS749511928 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749512075 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 4, Myofibrillar myopathy 4 |
| RS749512704 |
BLM
|
Health Risk |
Pathogenic |
Bloom syndrome, Bloom syndrome |
| RS749512886 |
GLDC
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy 1 |
| RS749512960 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS749513254 |
DLL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Spondylocostal dysostosis 1, autosomal recessive |
| RS749515743 |
MATN3
|
Health Risk |
Likely pathogenic |
Osteoarthritis susceptibility 2, Osteoarthritis susceptibility 2 |
| RS749515977 |
PACS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schuurs-Hoeijmakers syndrome, Inborn genetic diseases |
| RS749516565 |
CFI
|
Health Risk |
Pathogenic |
— |
| RS749516893 |
ALDH7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyridoxine-dependent epilepsy, Pyridoxine-dependent epilepsy |
| RS749519562 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
COL7A1-related disorder, Inborn genetic diseases |
| RS749520022 |
A2ML1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |