| RS74957591 |
RPGRIP1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS749577520 |
NF1
|
Health Risk |
Pathogenic |
Neurofibromatosis, type 1 |
| RS749578252 |
SLC2A10
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Familial thoracic aortic aneurysm and aortic dissection |
| RS749578295 |
USH2A
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 39, Retinitis pigmentosa 39 |
| RS749578474 |
GALNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-IV-A |
| RS749579925 |
RFXANK
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class II deficiency, MHC class II deficiency |
| RS749580328 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS749580877 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal Kniest-like syndrome, Schwartz-Jampel syndrome |
| RS749583615 |
CC2D2A
|
Health Risk |
Likely pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS749583854 |
COMP
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple epiphyseal dysplasia type 1, Multiple epiphyseal dysplasia type 1 |
| RS749584082 |
KIDINS220
|
Health Risk |
Conflicting classifications of pathogenicity |
KIDINS220-related disorder, Inborn genetic diseases |
| RS749584249 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS749584277 |
GNPTAB
|
Health Risk |
Pathogenic |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS749584846 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS749586225 |
DHFR;MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
MSH3-related disorder, Hereditary cancer-predisposing syndrome |
| RS749587119 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS749587320 |
MED13L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Dextro-looped transposition of the great arteries |
| RS749587463 |
DRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749588235 |
FARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 77, Combined oxidative phosphorylation defect type 14 |
| RS749588699 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS749590229 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS749590293 |
CITED2
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial septal defect 8, CITED2-related disorder |
| RS749590736 |
SETD1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749591910 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary diffuse gastric adenocarcinoma |
| RS749593004 |
COL6A2
|
Health Risk |
Pathogenic/Likely pathogenic |
Ullrich congenital muscular dystrophy 1A, Bethlem myopathy 1A |
| RS749593050 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Lymphangiomyomatosis |
| RS749593461 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS749595462 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749596514 |
IFIH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Singleton-Merten syndrome 1, Aicardi-Goutieres syndrome 7 |
| RS749596892 |
ELP1
|
Health Risk |
Pathogenic |
— |
| RS749597090 |
GALC
|
Health Risk |
Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS749597091 |
GNB5
|
Health Risk |
Pathogenic/Likely pathogenic |
Gnb5-related intellectual disability-cardiac arrhythmia syndrome, Inborn genetic diseases |
| RS749598296 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS749598830 |
ACADVL
|
Health Risk |
Conflicting classifications of pathogenicity |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS749599371 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, Cystic fibrosis |
| RS749599838 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS749600689 |
TAF15
|
Health Risk |
Conflicting classifications of pathogenicity |
TAF15-related disorder, TAF15-related disorder |
| RS749602688 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS749602970 |
DAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A9 |
| RS749603273 |
PRPH2
|
Health Risk |
Likely pathogenic |
PRPH2-related disorder, Retinal dystrophy |
| RS749603354 |
POMGNT1
|
Health Risk |
Pathogenic |
Muscle eye brain disease, Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability) |
| RS749605438 |
NOD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Blau syndrome, Regional enteritis |
| RS749605981 |
KBTBD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 6, Inborn genetic diseases |
| RS749606141 |
CTRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pancreatitis, Hereditary pancreatitis |
| RS749606240 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS749606788 |
NPHP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Nephronophthisis |
| RS749606885 |
NCF2
|
Health Risk |
Pathogenic/Likely pathogenic |
Granulomatous disease, chronic |
| RS749607205 |
ANKRD11
|
Health Risk |
Pathogenic |
KBG syndrome, KBG syndrome |
| RS749608995 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749610328 |
PRPF6
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS749610641 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS749611797 |
B9D1
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel syndrome, type 9 |
| RS749611934 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749613899 |
PAH
|
Health Risk |
Likely pathogenic |
Phenylketonuria, Phenylketonuria |
| RS749615956 |
GALC
|
Health Risk |
Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS749616160 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia, Spastic paraplegia |
| RS749616545 |
WRN
|
Health Risk |
Pathogenic |
Werner syndrome, Werner syndrome |
| RS749616603 |
PRDM5
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS749616608 |
RAB3GAP1
|
Health Risk |
Pathogenic/Likely pathogenic |
RAB3GAP1-related disorder, RAB3GAP1-related disorder |
| RS749617848 |
SIX6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749617913 |
ALOX12B
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive congenital ichthyosis 2, Autosomal recessive congenital ichthyosis 2 |
| RS749619355 |
COL4A6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749619435 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS749619625 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease, adult type |
| RS749620886 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749621457 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 39, Usher syndrome type 2A |
| RS749621716 |
SETD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Luscan-Lumish syndrome, Inborn genetic diseases |
| RS749621872 |
COL1A2
|
Health Risk |
Pathogenic |
Ehlers-Danlos syndrome, classic type |
| RS749621890 |
EXTL3
|
Health Risk |
Pathogenic/Likely pathogenic |
Immunoskeletal dysplasia with neurodevelopmental abnormalities, Immunoskeletal dysplasia with neurodevelopmental abnormalities |
| RS749622044 |
IL10RA
|
Health Risk |
Conflicting classifications of pathogenicity |
Inflammatory bowel disease 28, Inflammatory bowel disease 28 |
| RS749622191 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS749624669 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS749625288 |
LIPA
|
Health Risk |
Likely pathogenic |
Lysosomal acid lipase deficiency, Lysosomal acid lipase deficiency |
| RS749626453 |
CSNK2A1
|
Health Risk |
Likely pathogenic |
Okur-Chung neurodevelopmental syndrome, Okur-Chung neurodevelopmental syndrome |
| RS749626601 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS749626631 |
TBC1D24
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Developmental and epileptic encephalopathy |
| RS749626865 |
STAR
|
Health Risk |
Likely pathogenic |
Congenital lipoid adrenal hyperplasia due to STAR deficency, Congenital lipoid adrenal hyperplasia due to STAR deficency |
| RS749627411 |
LARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Perrault syndrome 4, Perrault syndrome |
| RS749628937 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS749630029 |
RARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pontocerebellar hypoplasia type 6, Pontocerebellar hypoplasia type 6 |
| RS749630366 |
PIGO
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperphosphatasia with intellectual disability syndrome 2, Hyperphosphatasia with intellectual disability syndrome 2 |
| RS749630454 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749631362 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Facial dysmorphism-immunodeficiency-livedo-short stature syndrome |
| RS749631821 |
MED17
|
Health Risk |
Pathogenic/Likely pathogenic |
Infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly, Infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly |
| RS749632423 |
HPS3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hermansky-Pudlak syndrome 3, Hermansky-Pudlak syndrome 3 |
| RS749632782 |
ANKRD11
|
Health Risk |
Pathogenic |
KBG syndrome, Intellectual disability |
| RS749633038 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS749633059 |
SNAP29
|
Health Risk |
Pathogenic |
— |
| RS749633105 |
CPT1A
|
Health Risk |
Likely pathogenic |
Carnitine palmitoyl transferase 1A deficiency, Carnitine palmitoyl transferase 1A deficiency |
| RS749633223 |
SACS
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS749633483 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Isolated focal cortical dysplasia type II |
| RS749633616 |
SAG
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS749633685 |
HNF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young, 6 conditions |
| RS749633690 |
DOCK8
|
Health Risk |
Likely pathogenic |
Combined immunodeficiency due to DOCK8 deficiency, Combined immunodeficiency due to DOCK8 deficiency |
| RS749633839 |
ERBB2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749633941 |
VPS13C
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749634060 |
SMCHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Facioscapulohumeral muscular dystrophy 2 |
| RS749634352 |
ERCC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group Q, Xeroderma pigmentosum |
| RS749635212 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS749635819 |
WHRN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |