| RS749520121 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 4 |
| RS749520412 |
KBTBD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Nemaline myopathy 6 |
| RS749520560 |
GUSB
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis type 7, Mucopolysaccharidosis type 7 |
| RS749522324 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy |
| RS749522534 |
MSH6
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Lynch syndrome 5 |
| RS749522728 |
LAMA2
|
Health Risk |
Pathogenic |
Merosin deficient congenital muscular dystrophy, LAMA2-related muscular dystrophy |
| RS749523755 |
CPLANE1
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome 17, Jaundice |
| RS749523973 |
BMPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary pulmonary hypertension, Inborn genetic diseases |
| RS749526038 |
LPIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Majeed syndrome |
| RS749526415 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS749526785 |
ABCA4
|
Health Risk |
Pathogenic/Likely pathogenic |
Cone-rod dystrophy 3, Retinitis pigmentosa |
| RS749527439 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749527800 |
ITGB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa with pyloric atresia, Junctional epidermolysis bullosa with pyloric atresia |
| RS749527870 |
SDHAF2
|
Health Risk |
Likely pathogenic |
Hereditary pheochromocytoma and paraganglioma, Hereditary cancer-predisposing syndrome |
| RS749528768 |
WDR62
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 2, primary |
| RS749529161 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS749529577 |
ACADM
|
Health Risk |
Pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS749529856 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS749530596 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS749532705 |
HSD17B4
|
Health Risk |
Pathogenic/Likely pathogenic |
Bifunctional peroxisomal enzyme deficiency, Perrault syndrome |
| RS74953290 |
APC
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial colorectal cancer, Familial adenomatous polyposis 1 |
| RS749533073 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Duchenne muscular dystrophy |
| RS749533743 |
PEX26
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 7A (Zellweger), Peroxisome biogenesis disorder 7B |
| RS749534144 |
FBXO7
|
Health Risk |
Pathogenic/Likely pathogenic |
Parkinsonian-pyramidal syndrome, Parkinsonian-pyramidal syndrome |
| RS749536123 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Tuberous sclerosis syndrome |
| RS749536178 |
RORB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749537392 |
ATF6
|
Health Risk |
Likely pathogenic |
Macular dystrophy, Macular dystrophy |
| RS749537609 |
CYP27B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Vitamin D-dependent rickets, type 1A |
| RS749538361 |
ACSF3
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS749539343 |
RRAS
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS749539763 |
CACNA2D2
|
Health Risk |
Likely pathogenic |
Early-infantile DEE, Early-infantile DEE |
| RS749541171 |
COL18A1
|
Health Risk |
Pathogenic |
COL18A1-related disorder, COL18A1-related disorder |
| RS749541256 |
EP300
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome due to EP300 haploinsufficiency, Rubinstein-Taybi syndrome due to EP300 haploinsufficiency |
| RS749541995 |
SLC16A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Spastic paraplegia |
| RS749542089 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS749542623 |
GLDC
|
Health Risk |
Pathogenic |
— |
| RS749542896 |
LARS1
|
Health Risk |
Likely pathogenic |
— |
| RS749543152 |
MSH2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS749543313 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS749543411 |
SYNE1
|
Health Risk |
Pathogenic |
Autosomal recessive ataxia, Beauce type |
| RS749543418 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate E, Focal segmental glomerulosclerosis 5 |
| RS749544042 |
ALPL
|
Health Risk |
Pathogenic |
Perinatal lethal hypophosphatasia, Infantile hypophosphatasia |
| RS749544685 |
SLC45A2
|
Health Risk |
Conflicting classifications of pathogenicity |
SKIN/HAIR/EYE PIGMENTATION 5, BLACK/NONBLACK HAIR |
| RS749545274 |
ADAMTSL4
|
Health Risk |
Pathogenic |
— |
| RS749545338 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS749545528 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
FLNB-Related Spectrum Disorders, FLNB-Related Spectrum Disorders |
| RS749547712 |
CASQ2
|
Health Risk |
Pathogenic/Likely pathogenic |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia 2 |
| RS749548033 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS749548287 |
ELP1
|
Health Risk |
Likely pathogenic |
— |
| RS749548928 |
POGZ
|
Health Risk |
association |
Autism spectrum disorder, Autism spectrum disorder |
| RS74954894 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1E, Ventricular fibrillation |
| RS749548974 |
ITGB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa, junctional 5A |
| RS749549494 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749549682 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS749549856 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS749550071 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS749550737 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS749551110 |
ADAMTS17
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani 4 syndrome, recessive |
| RS749551841 |
OCRL
|
Health Risk |
Conflicting classifications of pathogenicity |
Lowe syndrome, Lowe syndrome |
| RS749552053 |
UGT1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749552056 |
CLCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Abnormality of the musculature, Congenital myotonia |
| RS749552242 |
DUOX2
|
Health Risk |
Pathogenic |
Thyroid dyshormonogenesis 6, Thyroid dyshormonogenesis 6 |
| RS749552415 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS749553271 |
HFE
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary hemochromatosis, Hemochromatosis type 1 |
| RS749554385 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, Inborn genetic diseases |
| RS749554659 |
LOXHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 77, Autosomal recessive nonsyndromic hearing loss 77 |
| RS749555560 |
BLOC1S6
|
Health Risk |
Pathogenic |
Hermansky-Pudlak syndrome 9, Hermansky-Pudlak syndrome 9 |
| RS749556191 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, NEB-related disorder |
| RS749556197 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS749556778 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS749557617 |
FKTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Walker-Warburg congenital muscular dystrophy, FKTN-related disorder |
| RS749558026 |
EGR2
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease, type I |
| RS749559501 |
ASL
|
Health Risk |
Conflicting classifications of pathogenicity |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS749560316 |
PYGM
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type V |
| RS749561286 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, NOTCH3-related disorder |
| RS749561945 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749562548 |
PLCZ1
|
Health Risk |
Pathogenic |
Spermatogenic failure 17, Spermatogenic failure 17 |
| RS749563050 |
IFT140
|
Health Risk |
Likely pathogenic |
Saldino-Mainzer syndrome, Retinitis pigmentosa 80 |
| RS749563094 |
TJP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749563704 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Primary dilated cardiomyopathy |
| RS749563734 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS749565002 |
TCAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2G, Hypertrophic cardiomyopathy 25 |
| RS749565347 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS749565877 |
KCNQ4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749566145 |
LAMA2
|
Health Risk |
Pathogenic/Likely pathogenic |
LAMA2-related muscular dystrophy, Merosin deficient congenital muscular dystrophy |
| RS749566947 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Mitochondrial complex II deficiency |
| RS749567006 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS749567608 |
FMN2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749567617 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Osteogenesis imperfecta type I |
| RS749568919 |
HGSNAT
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis, MPS-III-C |
| RS749570458 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS749571160 |
KMT2C
|
Health Risk |
Pathogenic/Likely pathogenic |
Kleefstra syndrome 2, KMT2C-related disorder |
| RS749571434 |
BMPR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Juvenile polyposis syndrome |
| RS749571474 |
DPYD
|
Health Risk |
Pathogenic/Likely pathogenic |
Dihydropyrimidine dehydrogenase deficiency, Dihydropyrimidine dehydrogenase deficiency |
| RS749573024 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS749574677 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group A, Fanconi anemia complementation group A |
| RS749575443 |
DOCK8
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to DOCK8 deficiency, Acute myeloid leukemia |
| RS749575477 |
CNTNAP2
|
Health Risk |
Pathogenic |
Cortical dysplasia-focal epilepsy syndrome, Cortical dysplasia-focal epilepsy syndrome |
| RS749575769 |
SOX9
|
Health Risk |
Conflicting classifications of pathogenicity |
Camptomelic dysplasia, Camptomelic dysplasia |
| RS749575902 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |